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  • Hellberg, Ann-Sofie
    et al.
    Örebro University, Örebro University School of Business.
    Islam, Sirajul
    Örebro University, Örebro University School of Business.
    Karlsson, Fredrik
    Örebro University, Örebro University School of Business.
    Säkerhet vid molnlösningar2018Report (Other academic)
  • Kullenberg, Christopher
    et al.
    Department of Philosophy, Linguistics and Theory of Science, University of Gothenburg, Gothenburg, Sweden.
    Rohden, Frauke
    Department of Philosophy, Linguistics and Theory of Science, University of Gothenburg, Gothenburg, Sweden.
    Björkvall, Anders
    Örebro University, School of Humanities, Education and Social Sciences.
    Brounéus, Fredrik
    VA (Public & Science), Stockholm, Sweden.
    Avellan-Hultman, Anders
    Stockholm, Sweden.
    Järlehed, Johan
    Department of Languages and Literatures, University of Gothenburg, Gothenburg, Sweden.
    Van Meerbergen, Sara
    Department of Slavic and Baltic Studies, Finnish, Dutch and German, Stockholm University, Stockholm, Sweden.
    Nord, Andreas
    Department of Swedish, University of Gothenburg, Gothenburg, Sweden.
    Lykke Nielsen, Helle
    Department of Languages and Literatures, University of Gothenburg, Gothenburg, Sweden; Department of History, University of Southern Denmark, Odense, Denmark.
    Rosendal, Tove
    Department of Languages and Literatures, University of Gothenburg, Gothenburg, Sweden.
    Tomasson, Lotta
    VA (Public & Science), Stockholm, Sweden.
    Westberg, Gustav
    Department of Swedish Language and Multilingualism, Stockholm University, Stockholm, Sweden.
    What are analog bulletin boards used for today?: Analysing media uses, intermediality and technology affordances in Swedish bulletin board messages using a citizen science approach2018In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 13, no 8, article id e0202077Article in journal (Refereed)
    Abstract [en]

    Analog bulletin boards are omnipresent in Swedish urban areas, yet little systematic knowledge about this communication medium exists. In the shadow of the rapid emergence of digital media the analog bulletin board has received less attention than its digital successors, many of them having incorporated similar functionality with novel technical solutions. In this study we used a citizen science method to collect 1167 messages from bulletin boards around Sweden aided by school children and teachers, with the purpose of shedding new light on what is communicated on the boards, by whom, using what types of technologies and in what way the messages refer to other media. Results show that the most common messages are invitations to events, such as concerts, lectures and sports events, followed by buy-and-sell ads for goods and services. The most frequent sender is an association, for example NGOs, sports associations or religious communities. Almost half of the sampled messages were professionally printed, about forty per cent were made by home printers. Only six per cent of the messages were handwritten, almost exclusively by private persons as senders. Moreover, we show how the analog bulletin board has adapted to recent changes in media technology—a media landscape which is saturated with electronic- and mobile media. Further, the bulletin board still holds a firm place in a media ecology where local communication is in demand, and exists in parallel with electronic media. Close to forty percent of the messages contained hyperlinks to web pages and we found (and removed for anonymization purposes) more than six hundred phone numbers from the dataset.

  • Arensmeier, Cecilia
    Örebro University, School of Humanities, Education and Social Sciences.
    Different Expectations in Civic Education: A Comparison of Upper-Secondary School Textbooks in Sweden2018In: Journal of Social Science Education, ISSN 1611-9665, E-ISSN 1618-5293, Vol. 17, no 2, p. 5-20Article in journal (Refereed)
    Abstract [en]

    Purpose: The aim of the article is to examine civic education in Sweden with regard to equality, by comparing curricula and textbooks for social studies in different tracks in upper-secondary school.

    Method: The study is based on qualitative text analysis, with quantitative features. The analysis maps themes covered, the extent and depth of thematic coverage, and amount of emphasis on conceptual understanding and analytical training.

    Findings: The results point to some similarities between the tracks; limited attention is given to democratic values and civic engagement, apart from voting. Clear differences are found in amount of information and complexity. The most basic textbooks target the vocational track, while (some of) the textbooks for the academic track have an elaborated focus on complex conceptual understanding and analytical training.

    Practical implications: The findings indicate different expectations in civic education. Vocational students receive more limited opportunities to develop civic abilities, which might negatively affect the exercise of citizenship and increase political inequality.

  • Tolgfors, Björn
    Örebro University, School of Health Sciences.
    Transformative assessment in the subject of physical education.2018Conference paper (Refereed)
  • Ziegler, Ingrid
    Örebro University, School of Medical Sciences.
    Quantitative detection of bacterial DNA in whole blood in bloodstream infection2018Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    This thesis aims to increase the knowledge on how quantitative PCR can be used in the diagnostics of bloodstream infections, with an emphasis on quantitative elements.

    In Papers I and II, we evaluated quantitative data from two commercial PCR tests for pathogen detection directly in blood, Magicplex Sepsis (I) and SeptiFast (II), from patients with suspected sepsis. We found that high quantification cycle (Cq) values, indicating low DNA loads, were associated with findings of pathogens with doubtful clinical relevance, whereas low Cq values, indicating high DNA loads, were correlated with sepsis and septic shock, as well as with positive blood culture results.

    In Paper III, we aimed to study the bacterial DNA load during Staphylococcus aureus bacteremia, in relation to different clinical factors. For this purpose, we developed a droplet digital PCR (ddPCR) for precise DNA quantification, targeting S. aureus specifically. We found that a high initial S. aureus DNA load was associated with laboratory markers for immune dysregulation as well as with sepsis, endocarditis, and mortality.

    In Paper IV, we aimed to develop a tool for repeated DNA quantification during bloodstream infection. For this purpose, we optimized a ddPCR, targeting the universal bacterial 16S rDNA, and performed a comparison with species-specific ddPCRs on spiked blood, and on clinical samples. The performance of the16S rDNA ddPCR was adequate, and we found that a high 16S rDNA load was associated with sepsis and mortality.

    In conclusion, our results indicate that the pathogen DNA load in blood plays an important role in the clinical picture in BSI. In future research on molecular BSI diagnostics, studies on DNA loads and clearance should be included.

    List of papers
    1. Evaluation of a Commercial Multiplex PCR Assay for Detection of Pathogen DNA in Blood from Patients with Suspected Sepsis
    Open this publication in new window or tab >>Evaluation of a Commercial Multiplex PCR Assay for Detection of Pathogen DNA in Blood from Patients with Suspected Sepsis
    2016 (English)In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 11, no 12, article id e0167883Article in journal (Refereed) Published
    Abstract [en]

    The Magicplex Sepsis Real-time Test (MST) is a commercial multiplex PCR that can detect more than 90 different pathogens in blood, with an analysis time of six hours. The aim of the present study was to evaluate this method for the detection of bloodstream infection (BSI). An EDTA whole blood sample for MST was collected together with blood cultures (BC) from patients with suspected sepsis at the Emergency Department of a university hospital. Among 696 study patients, 322 (46%) patients were positive with at least one method; 128 (18%) were BC positive and 268 (38%) were MST positive. Considering BC to be the gold standard, MST had an overall sensitivity of 47%, specificity of 66%, positive predictive value (PPV) of 23%, and a negative predictive value of 87%. Among the MST positive samples with a negative BC, coagulase-negative staphylococci (CoNS) and species that rarely cause community-acquired BSI were frequently noted. However, the quantification cycle (Cq) values of the MST+/BC- results were often high. We thus hypothesized that the performance of the MST test could be improved if the Cq cut-off level was adjusted downwards. With a lower Cq cut-off value, i.e. 6.0 for Staphylococcus species and 9.0 for all other species, the number of MST positive cases decreased to 83 (12%) and the overall sensitivity decreased to 38%. However, the PPV increased to 59% and the specificity increased to 96%, as many MST positive results for CoNS and bacteria that rarely cause community-acquired BSI turned MST negative. In conclusion, our study shows that with a lower Cq cut-off value, the MST will detect less contaminants and findings with unclear relevance, but to the cost of a lower sensitivity. Consequently, we consider that a positive MST results with a Cq value above the adjusted cut-off should be interpreted with caution, as the result might be clinically irrelevant. In a correspondent way, quantitative results could probably be useful in the interpretation of positive results from other molecular assays for the detection of BSI.

    Place, publisher, year, edition, pages
    San Francisco, USA: Public Library of Science, 2016
    National Category
    Clinical Laboratory Medicine
    Identifiers
    urn:nbn:se:oru:diva-54404 (URN)10.1371/journal.pone.0167883 (DOI)000392842900017 ()27997618 (PubMedID)2-s2.0-85006866953 (Scopus ID)
    Note

    Funding Agency:

    Resaerch committee of Region Örebro Län

    Available from: 2017-02-07 Created: 2017-01-10 Last updated: 2018-09-12Bibliographically approved
    2. Quantitative data from the SeptiFast real-time PCR is associated with disease severity in patients with sepsis
    Open this publication in new window or tab >>Quantitative data from the SeptiFast real-time PCR is associated with disease severity in patients with sepsis
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    2014 (English)In: BMC Infectious Diseases, ISSN 1471-2334, E-ISSN 1471-2334, Vol. 14, no 1, article id 155Article in journal (Refereed) Published
    Abstract [en]

    Background: The commercial test, SeptiFast, is designed to detect DNA from bacterial and fungal pathogens in whole blood. The method has been found to be specific with a high rule-in value for the early detection of septic patients. The software automatically provides information about the identified pathogen, without quantification of the pathogen. However, it is possible to manually derive Crossing point (Cp) values, i.e. the PCR cycle at which DNA is significantly amplified. The aim of this study was to find out whether Cp values correlate to disease severity.

    Methods: We used a study cohort of patients with positive results from SeptiFast tests for bacteria from a recent study which included patients with suspected sepsis in the Emergency department. Cp values were compared with disease severity, classified as severe sepsis/septic shock or non-severe sepsis, according to the criteria of the American College of Chest Physicians/Society of Critical Care Medicine.

    Results: Ninety-four patients were included. The prevalence of severe sepsis/septic shock in the study was 29%. SeptiFast positive tests from patients with severe sepsis/septic shock had significantly lower Cp values compared with those from patients with non-severe sepsis, median 16.9 (range: 7.3 - 24.3) versus 20.9 (range: 8.5 - 25.0), p < 0.001. Positive predictive values from the SeptiFast test for identifying severe sepsis/septic shock were 34% at Cp cut-off <25.0, 35% at Cp cut-off <22.5, 50% at Cp cut-off <20.0, and 73% at Cp cut-off <17.5. Patients with a positive Septifast test with a Cp value <17.5 had significantly more severe sepsis/septic shock (73% versus 15%, p < 0.001), were more often admitted to the Intensive Care Unit (23% versus 4%, p = 0.016), had positive blood culture (BC) more frequently (100% versus 32%, p < 0.001) and had longer hospital stays (median 19.5 [range: 4 - 78] days versus 5 [range: 0 - 75] days, p < 0.001) compared with those with a Cp value >17.5.

    Conclusions: Our results suggest that introducing quantitative data to the SeptiFast test could be of value in assessing sepsis severity. Moreover, such data might also be useful in predicting a positive BC result.

    Place, publisher, year, edition, pages
    London: BioMed Central, 2014
    Keywords
    Polymerase-chain-reaction, blood-stream infections, staphylococcus-aureus bacteremia, genomic bacterial load, rapid detection, united-states, pathogens, diagnosis, culture, epidemiology
    National Category
    Infectious Medicine
    Research subject
    Infectious Diseases
    Identifiers
    urn:nbn:se:oru:diva-34951 (URN)10.1186/1471-2334-14-155 (DOI)000333601600004 ()24656148 (PubMedID)2-s2.0-84899124239 (Scopus ID)
    Note

    Funding Agency:

    Research Committee of the Örebro County Council

    Available from: 2014-05-05 Created: 2014-05-05 Last updated: 2018-09-12Bibliographically approved
    3. nuc DNA in Whole blood in Relation to Immune dysregulation, Sepsis, and Mortality in Staphylococcus aureus Bacteremia
    Open this publication in new window or tab >>nuc DNA in Whole blood in Relation to Immune dysregulation, Sepsis, and Mortality in Staphylococcus aureus Bacteremia
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    (English)Manuscript (preprint) (Other academic)
    National Category
    General Practice
    Identifiers
    urn:nbn:se:oru:diva-68880 (URN)
    Available from: 2018-09-12 Created: 2018-09-12 Last updated: 2018-09-12Bibliographically approved
    4. 16S rDNA droplet digital PCR for monitoring bacterial DNAemia in bloodstream infections
    Open this publication in new window or tab >>16S rDNA droplet digital PCR for monitoring bacterial DNAemia in bloodstream infections
    Show others...
    (English)Manuscript (preprint) (Other academic)
    National Category
    General Practice
    Identifiers
    urn:nbn:se:oru:diva-68881 (URN)
    Available from: 2018-09-12 Created: 2018-09-12 Last updated: 2018-09-12Bibliographically approved
  • Bajramović, Sanela
    Örebro University, School of Humanities, Education and Social Sciences.
    Hierarchical Sisterhood: Supporting Women's Peacebuilding through Swedish Aid to Bosnia and Herzegovina 1993-20132018Doctoral thesis, monograph (Other academic)
    Abstract [en]

    This dissertation examines possibilities and challenges faced by international interveners in a post-socialist and violently divided area. The study object is the Swedish foundation Kvinna till Kvinna, formed in 1993 during the Bosnian war, originating from the peace movement and supported by the Swedish government aid agency Sida. The aim is to contextualize and analyze Kvinna till Kvinna’s two decades of engagement in peacebuilding in Bosnia. The encounter with domestic women’s NGOs is of particular interest. By focusing on rhetoric, practice and silences, the ambition has been to understand the international/local relationship from the perspective of both actors.

      In terms of methodology, this study combines a hermeneutic approach with that of oral history. The empirical material utilized consists of both written and oral sources, the majority of which appear in research for the first time. To capture the complexity of the peacebuilding endeavor, critically scrutinize it and discern its benevolence, this research draws inspiration from postcolonial and semiperipherality theories, as well as influential theorizing on peacebuilding, sisterhood and solidarity.

      This study shows that even well-intentioned, locally-focused external efforts, constrained by donor agendas and circumstances on the ground, contain problematic characteristics common in the era of liberal peace. While subscribing to the idea of transnational sisterhood, Kvinna till Kvinna also presented a belief in Swedish supremacy and demonstrated a lack of interest in local knowledge. It sought to educate and change its Bosnian counterparts by using soft methods. Further, the findings challenge idealized images of the ‘local’ as a peace-loving force for change and a powerless victim of Western domination. The hierarchical sisterhood that over time evolved between the two actors, founded on basic shared values related to women’s situation, was driven by mutual benefit. Acknowledging advantages of this type of transnational encounters in peacebuilding contexts, the study raises questions about dilemmas in them and underlines the importance of rhetorical listening.

  • Díaz Reviriego, Isabel
    et al.
    Beck, Silke
    Darbi, Marianne
    Hauck, Jennifer
    Hudson, Christian
    Janz, Christophe
    Klenk, Nicole
    Lidskog, Rolf
    Örebro University, School of Humanities, Education and Social Sciences.
    Marquard, Elisabeth
    Montana, Jasper
    Obermeister, Noam
    Raab, Kristina
    Schoolenberg, Mactheld
    Settele, Josef
    Turnhout, Esther
    Neßhöver, Carsten
    Five years of IPBES : Reflecting the achievements and challenges and identifying needs for its review towards a 2nd work programme.  2018Report (Other academic)
    Abstract [en]

    On 17 to 19th October 2017, twenty-four academics and practitioners with diverse inter- and transdisciplinary experiences gathered for a workshop to collectively reflect on IPBES’ work and performance. The workshop was held at the German Centre for Integrative Biodiversity Research (iDiv) in Leipzig. The workshop and this report represent an effort to proactively contribute to IPBES’ ongoing (external) review process. The external review process opens up a window of opportunity towards re-thinking the very purpose of IPBES and identifying new pathways to live up to its initial ambitions, such as to move beyond assessments. The workshop identified a spectrum of potential opportunities, provided visions for the future work of IPBES, and collected insights into how to cope with them. While the workshop focussed on identifying future challenges and possible solutions, all participants underlined the great achievements that IPBES has already accomplished. This report provides a synthesis of the workshop discussions. The main recommendations for the external review were:

     - The external review should seize the opportunity to establish itself in a responsive and future-oriented way so that it not only assesses past performance but also facilitates learning and identifies new pathways for IPBES. It is important that the focus of the review is not just on the extent to which IPBES has fulfilled its ambitions but also on the efficiency with which it has done this, and on the potential unintended effects of decisions.

     - For IPBES to achieve its initial ambitions, strengthening the (mainly global-scale) scientific knowledge base behind assessments is necessary but not yet sufficient. To meet its broader set of goals, it is required to pay critical attention to all aspects of policy support, knowledge generation and capacity-building, including the meaningful participation of Indigenous Peoples and Local Communities and the incorporation of local and indigenous knowledge. This will require building synergies between knowledge systems, promoting the engagement of the social sciences and humanities, and addressing current challenges in the nomination and selection procedures for the identification of experts.

     - The external review also opens up space to identify a full range of alternative options and choices that are available when reforming IPBES. The review should engage in real-world dialogues and liaise closely with partners from research, policy and practice as well as with national platforms and local actors.

  • Mielle, Malcolm
    et al.
    Örebro University, School of Science and Technology.
    Magnusson, Martin
    Örebro University, School of Science and Technology.
    Lilienthal, Achim J.
    Örebro University, School of Science and Technology.
    A method to segment maps from different modalities using free space layout MAORIS: map of ripples segmentation2018Conference paper (Refereed)
    Abstract [en]

    How to divide floor plans or navigation maps into semantic representations, such as rooms and corridors, is an important research question in fields such as human-robot interaction, place categorization, or semantic mapping. While most works focus on segmenting robot built maps, those are not the only types of map a robot, or its user, can use. We present a method for segmenting maps from different modalities, focusing on robot built maps and hand-drawn sketch maps, and show better results than state of the art for both types.

    Our method segments the map by doing a convolution between the distance image of the map and a circular kernel, and grouping pixels of the same value. Segmentation is done by detecting ripple-like patterns where pixel values vary quickly, and merging neighboring regions with similar values.

    We identify a flaw in the segmentation evaluation metric used in recent works and propose a metric based on Matthews correlation coefficient (MCC). We compare our results to ground-truth segmentations of maps from a publicly available dataset, on which we obtain a better MCC than the state of the art with 0.98 compared to 0.65 for a recent Voronoi-based segmentation method and 0.70 for the DuDe segmentation method.

    We also provide a dataset of sketches of an indoor environment, with two possible sets of ground truth segmentations, on which our method obtains an MCC of 0.56 against 0.28 for the Voronoi-based segmentation method and 0.30 for DuDe.

  • Nilsson, Per
    et al.
    Örebro University, School of Science and Technology.
    Schindler, Maike
    University of Cologne, Cologne, Germany .
    The nature and use of theories in statistics education: looking back, looking forward2018In: Looking back, looking forward / [ed] M. A. Sorto, A. White, & L. Guyot, Voorburg, The Netherlands: The International Statistical Institute, 2018Conference paper (Refereed)
    Abstract [en]

    Theories have a significant role for scientific work—also for statistics education research (SER). This paper elaborates on the use of theories in SER, based on findings of a literature review on the nature and use of theories in SER. In particular, we address theoretical issues and possible directions to further theory development in SER. Subsequently, we discuss five themes that in our view need further attention in SER. 

  • Folkesson, Mattias
    Örebro University, School of Health Sciences.
    Heat shock proteins in exercised human skeletal muscle2018Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Exercise is considered as an important stressor accompanied by concerted molecular and cellular changes leading to adaptations at the level of skeletal muscle size and function. An important protein family produced by cells in response to stressful conditions is the heat shock proteins (HSPs). It is suggested that the different HSPs play specific roles in acute and longterm responses to exercise-induced stress. The overall aim of this thesis was to explore the expression of four different HSPs (αB-crystallin, HSP27, HSP60 and HSP70) in human skeletal muscle exposed to exercise, with a special emphasis on the role played by HSP27 in the hypertrophy of human skeletal muscle.

    One of the major findings was the fibre type-specific expression of HSPs in resting human skeletal muscle, including the preferential expression of HSP27 in fast type II muscle fibres. Another finding was the occurrence of training background-related differences in the expression of HSPs. Also, a cytoplasmic relocation of HSP27, occurring specifically in type II muscle fibres, was shown in response to a single bout of resistance exercise. Interestingly, there were no corresponding changes in response to an endurance exercise bout, suggesting that HSP27 may be specifically involved in the adaptations to resistance exercise. In order to test this hypothesis, an in-vitro exercise model based on the electrical pulse stimulation (EPS) of muscle cells was developed. The EPS protocol, including an 8 h restitution period, induced a significant hypertrophy of muscle cells together with molecular changes similar to those previously described in response to exercise in humans. The role of HSP27 in the hypertrophy of human muscle cells was examined through the downregulation of HSP27. Based on data from morphological and microarray analyses, findings indicate that HSP27 is not mandatory for the hypertrophy of human muscle cells. Overall, the present thesis clarified the expression of different HSPs in human skeletal muscle and provided an in-vitro-based approach for the elucidation of the exact role played by HSPs in the adaptations of human skeletal muscle to exercise.

    List of papers
    1. The expression of heat shock protein in human skeletal muscle: effects of muscle fibre phenotype and training background
    Open this publication in new window or tab >>The expression of heat shock protein in human skeletal muscle: effects of muscle fibre phenotype and training background
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    2013 (English)In: Acta Physiologica, ISSN 1748-1708, E-ISSN 1748-1716, Vol. 209, no 1, p. 26-33Article in journal (Refereed) Published
    Abstract [en]

    Aim: Exercise-induced adaptations of skeletal muscle are related to training mode and can be muscle fibre type specific. This study aimed to investigate heat shock protein expression in type I and type II muscle fibres in resting skeletal muscle of subjects with different training backgrounds.

    Methods: Three groups of subjects were included: healthy active not engaged in any training programme (ACT, n = 12), resistance trained (RES, n = 6) and endurance trained (END, n = 8). Biopsies were obtained from vastus lateralis, and immunohistochemistry was performed using monoclonal antibodies against myosin heavy chain I and IIA, αB-crystallin, HSP27, HSP60 and HSP70.

    Results: In ACT and RES, but not in END, a fibre type–specific expression with higher staining intensity in type I than type II fibres was seen for αB-crystallin. The opposite (II > I) was found for HSP27 in subjects from ACT (6 of 12 subjects) and RES (3 of 6), whereas all subjects from END displayed uniform staining. HSP60 showed no fibre-specific expression. HSP70 displayed a fibre-specific expression pattern (I > II) in ACT (4 of 12), but not in END or RES.

    Conclusion: This study shows that the level of expression of the different HSPs in human skeletal muscle is influenced by muscle fibre phenotype. The fibre type–specific expression of HSP70 is influenced by resistance and endurance training, whereas those of αB-crystallin and HSP27 is influenced only by endurance training, suggesting the existence of a training-modality-specific action on the adaptive processes including heat shock proteins in human skeletal muscle.

    Place, publisher, year, edition, pages
    Wiley-Blackwell, 2013
    Keywords
    Adaptation, endurance, heat shock protein, immunohistochemistry, resistance
    National Category
    Sport and Fitness Sciences
    Research subject
    Sports Physiology/Medicine
    Identifiers
    urn:nbn:se:oru:diva-30127 (URN)10.1111/apha.12124 (DOI)000322950400006 ()23710799 (PubMedID)2-s2.0-84881557932 (Scopus ID)
    Note

    Funding agency:

    Nordea Foundation

    Available from: 2013-08-06 Created: 2013-08-06 Last updated: 2018-11-19Bibliographically approved
    2. Immunohistochemical changes in the expression of HSP27 in exercised human vastus lateralis muscle
    Open this publication in new window or tab >>Immunohistochemical changes in the expression of HSP27 in exercised human vastus lateralis muscle
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    2008 (English)In: Acta Physiologica, ISSN 1748-1708, E-ISSN 1748-1716, Vol. 194, no 3, p. 215-222Article in journal (Refereed) Published
    Abstract [en]

    Aim: The role of HSP27 in the adaptive process of skeletal muscle to exercise, especially in humans, is not well understood. The objective of this study was to investigate immunohistochemical changes in HSP27 expression in human vastus lateralis muscle following resistance and endurance exercises.

    Methods: Two different exercise protocols were used: (1) one-leg ergometer cycling (EC, n = 6) consisting of two 30-min bouts at 40% and 75% of peak oxygen uptake, respectively, and (2) leg extension resistance exercise (RE, n = 9) including 10 sets of eight repetitions at a load corresponding to 70% of one maximal repetition (1RM). Immunohistochemistry using specific monoclonal antibodies was used to determine the location of HSP27 protein in muscle biopsies from human vastus lateralis.

    Results: Our results show that RE, but not EC, induced a significant appearance of scattered accumulations of HSP27 protein in muscle fibres from five of nine subjects. The number of fibres with accumulation of HSP27 in RE ranged from 0% to 32% with a mean of 6.3% of the total number of fibres.

    Conclusion: We conclude that this rapid HSP27 protein relocation after RE is an important player in the cellular remodelling of human muscle fibres in response to exercise involving high-force contractions, but not in response to endurance exercises.

    Place, publisher, year, edition, pages
    Blackwell Publishing, 2008
    Keywords
    adaptation, endurance and resistance exercise, fibre type, heat shock protein, stress response
    National Category
    Physiology
    Research subject
    Physiology
    Identifiers
    urn:nbn:se:oru:diva-4751 (URN)10.1111/j.1748-1716.2008.01875.x (DOI)000259863100005 ()18489727 (PubMedID)2-s2.0-53549112177 (Scopus ID)
    Funder
    Swedish National Centre for Research in Sports
    Available from: 2008-11-24 Created: 2008-11-24 Last updated: 2018-09-24Bibliographically approved
    3. Electrical pulse stimulation: an in vitro exercise model for the induction of human skeletal muscle cell hypertrophy. A proof-of-concept study
    Open this publication in new window or tab >>Electrical pulse stimulation: an in vitro exercise model for the induction of human skeletal muscle cell hypertrophy. A proof-of-concept study
    2017 (English)In: Experimental Physiology, ISSN 0958-0670, E-ISSN 1469-445X, Vol. 102, no 11, p. 1405-1413Article in journal (Refereed) Published
    Abstract [en]

    New Findings:

    • What is the central question of this study?

    Is electrical pulse stimulation (EPS) an in vitro exercise model able to elicit the hypertrophy of human muscle cells?

    • What is the main finding and its importance?

    The addition of a restitution period of 8h after EPS induces the enlargement of human muscle cells, a major physiological end-point to resistance exercise. This is supported by downregulationof myostatin, a negative regulator of muscle mass, and increased phosphorylated mTOR and 4E-BP1, key factors in the growth cascade. This proof-of-concept study provides a model of physiologically mediated muscle growth, which will be the basis for future studies aiming to depict molecular events governing the hypertrophy of human muscle cells.

    Electrical pulse stimulation (EPS) of muscle cells has previouslybeenused as an in vitro exercise model. The present study aimedto establish an EPS protocol promoting the hypertrophy ofhuman muscle cells, which represents a major physiological end-point to resistance exercise in humans. We hypothesized that adding a resting period after EPS would be crucial for the occurrence of the morphological change. Myoblasts obtained from human muscle biopsies (n=5) were differentiated into multinucleated myotubes and exposed to 8h of EPS consisting of 2ms pulses at 12V, with a frequency of 1Hz. Myotube size was assessed using immunohistochemistry immediately, 4 and 8h after completed EPS. Gene expression and phosphorylation status of selected markers of hypertrophy were assessed using RT-PCR and Western blotting, respectively. Release of the myokine interleukin-6 in culture medium was measured using enzyme-linked immunosorbent assay. We demonstrated a significant increase (31 +/- 14%; P=0.03) in the size of myotubes when EPS was followed by an 8h resting period, but not immediately or 4h after completion of EPS. The response was supported by downregulation (P=0.04) of the gene expression of myostatin, a negative regulator of muscle mass, and an increase in phosphorylated mTOR (P=0.03) and 4E-BP1 (P=0.01), which are important factors in the cellular growth signalling cascade. The present work demonstrates that EPS is an in vitro exercise model promoting the hypertrophy of human muscle cells, recapitulating a major physiological end-point to resistance exercise in human skeletal muscle.

    Place, publisher, year, edition, pages
    John Wiley & Sons, 2017
    Keywords
    Cell growth, muscle contraction, myotube morphology
    National Category
    Physiology
    Identifiers
    urn:nbn:se:oru:diva-61685 (URN)10.1113/EP086581 (DOI)000414175100010 ()28861930 (PubMedID)2-s2.0-85032974682 (Scopus ID)
    Available from: 2017-11-14 Created: 2017-11-14 Last updated: 2018-09-24Bibliographically approved
    4. HSP27 is not mandatory for the hypertrophy of human skeletal muscle cells
    Open this publication in new window or tab >>HSP27 is not mandatory for the hypertrophy of human skeletal muscle cells
    (English)Manuscript (preprint) (Other academic)
    National Category
    Physiology
    Identifiers
    urn:nbn:se:oru:diva-69017 (URN)
    Available from: 2018-09-24 Created: 2018-09-24 Last updated: 2018-09-24Bibliographically approved
  • Carling, Anna
    Örebro University, School of Medical Sciences.
    Impaired balance and fall risk in people with multiple sclerosis2018Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    The symptoms from the neurological disease multiple sclerosis vary from person to person and over time. Impaired balance is common in people with multiple sclerosis and can lead to falls. Fall frequency is high in people with multiple sclerosis, above 50%. Multiple sclerosis affects not only the person having the disease but also their next of kin. To be able to reduce fall risk it is important to know when, why and where people with multiple sclerosis fall, and how to improve balance and reduce falls with exercise. It is also important to know how the falls affect the residing next of kin to people with multiple sclerosis.

    The overall aim of this thesis was to gain enhanced knowledge by investigating when and why people with MS fall and how these falls possibly affect their next of kin, and also to evaluate the effects and perceptions of participating in a specific balance exercise.

    Data were gathered using four different data collections, and this thesis contains both qualitative and quantitative data.

    The major finding in this thesis is that people with multiple sclerosis fall in the course of everyday life activities, most often in their own homes due to various intrinsic and extrinsic factors. Balance can be improved and falls reduced and everyday life may be made easier and facilitated after participating in the CoDuSe balance exercise. This is important also for the next of kin, since they are adapting, adjusting and renouncing their activities due to the falls of the PwMS, in order to make it work for the whole family.

    List of papers
    1. Falls in people with multiple sclerosis: experiences of 115 fall situations
    Open this publication in new window or tab >>Falls in people with multiple sclerosis: experiences of 115 fall situations
    2018 (English)In: Clinical Rehabilitation, ISSN 0269-2155, E-ISSN 1477-0873, Vol. 32, no 4, p. 526-535Article in journal (Refereed) Published
    Abstract [en]

    Objectives: The aim was to describe falls and the perceived causes, experienced by people with multiple sclerosis shortly after falling.

    Design: A qualitative study using content analysis and quantitative data to illustrate where and why people report falls most commonly. Semi-structured telephone interviews were performed. Interviews were conducted shortly (0–10 days) after a fall.

    Subjects: In all, 67 informants who had reported at least one fall during the previous three-month period and who used a walking aid participated.

    Results: A total of 57 (85%) informants fell at least once during eight months resulting in 115 falls; 90 (78%) falls happened indoors, most commonly in the kitchen (n = 20; 17%) or bathroom (n = 16; 14%). Informants fell during everyday activities and walking aids had been used in more than a third of the reported falls. The falls were influenced of both intrinsic and extrinsic factors. Two categories emerged from the analysis: ‘activities when falling’ and ‘influencing factors’. The category contained three (basic activities of daily living, instrumental activities of daily living and leisure and work) and six (multiple sclerosis–related symptoms, fluctuating body symptoms, being distracted, losing body control, challenging surrounding and involvement of walking aid) subcategories, respectively.

    Conclusion: The majority of falls occurs indoors and in daily activities. Several factors interacted in fall situations and should be monitored and considered to reduce the gap between the person’s capacity and the environmental demands that cause fall risk. Fluctuation of bodily symptoms between and within a day is a variable not earlier targeted in multiple sclerosis fall risk research.

    Place, publisher, year, edition, pages
    Sage Publications, 2018
    Keywords
    Accidental falls, multiple sclerosis, walking aid, content analysis
    National Category
    Neurology Physiotherapy
    Identifiers
    urn:nbn:se:oru:diva-65948 (URN)10.1177/0269215517730597 (DOI)000429777600011 ()28901164 (PubMedID)2-s2.0-85042230415 (Scopus ID)
    Available from: 2018-03-22 Created: 2018-03-22 Last updated: 2018-11-19Bibliographically approved
    2. CoDuSe group exercise programme improves balance and reduces falls in people with multiple sclerosis: A multi-centre, randomized, controlled pilot study
    Open this publication in new window or tab >>CoDuSe group exercise programme improves balance and reduces falls in people with multiple sclerosis: A multi-centre, randomized, controlled pilot study
    2017 (English)In: Multiple Sclerosis, ISSN 1352-4585, E-ISSN 1477-0970, Vol. 23, no 10, p. 1394-1404Article in journal (Refereed) Published
    Abstract [en]

    Background: Imbalance leading to falls is common in people with multiple sclerosis (PwMS).

    Objective: To evaluate the effects of a balance group exercise programme (CoDuSe) on balance and walking in PwMS (Expanded Disability Status Scale, 4.0-7.5).

    Methods: A multi-centre, randomized, controlled single-blinded pilot study with random allocation to early or late start of exercise, with the latter group serving as control group for the physical function measures. In total, 14 supervised 60-minute exercise sessions were delivered over 7 weeks. Pretest-posttest analyses were conducted for self-reported near falls and falls in the group starting late. Primary outcome was Berg Balance Scale (BBS). A total of 51 participants were initially enrolled; three were lost to follow-up.

    Results: Post-intervention, the exercise group showed statistically significant improvement (p = 0.015) in BBS and borderline significant improvement in MS Walking Scale (p = 0.051), both with large effect sizes (3.66; -2.89). No other significant differences were found between groups. In the group starting late, numbers of falls and near falls were statistically significantly reduced after exercise compared to before (p < 0.001; p < 0.004).

    Conclusion: This pilot study suggests that the CoDuSe exercise improved balance and reduced perceived walking limitations, compared to no exercise. The intervention reduced falls and near falls frequency.

    Place, publisher, year, edition, pages
    London, United Kingdom: Sage Publications, 2017
    Keywords
    Accidental falls, exercise, multiple sclerosis, postural balance, core stability
    National Category
    Neurology
    Identifiers
    urn:nbn:se:oru:diva-53488 (URN)10.1177/1352458516677591 (DOI)000407918800014 ()27834736 (PubMedID)2-s2.0-85027895184 (Scopus ID)
    Note

    Funding Agencies:

    Uppsala-Örebro Regional Research Committe  

    Research committee of Örebro County Council  

    Norrbacka-Eugenia Foundation 

    Available from: 2016-11-14 Created: 2016-11-14 Last updated: 2018-11-19Bibliographically approved
    3. Balance exercise facilitates everyday life for people with multiple sclerosis: A qualitative study
    Open this publication in new window or tab >>Balance exercise facilitates everyday life for people with multiple sclerosis: A qualitative study
    2018 (English)In: Physiotherapy Research International, ISSN 1358-2267, E-ISSN 1471-2865, Vol. 23, no 4, article id e1728Article in journal (Refereed) Published
    Abstract [en]

    OBJECTIVES: The aim of this qualitative study was to describe the experience and perceived effects on everyday life for people with multiple sclerosis after participating in a balance exercise programme focusing on core stability, dual tasking, and sensory strategies (the CoDuSe programme).

    METHODS: A qualitative approach was chosen, using face-to-face interviews analysed with content analysis. Twenty-seven people with multiple sclerosis (20 women, 7 men) who had participated in the CoDuSe programme were included. All could walk 20 m with or without walking aids but could not walk further than 200 m. The CoDuSe programme was given twice weekly during a 7-week period.

    RESULTS: The analysis revealed five categories. Learning to activate the core muscles described how the participants gained knowledge of using their core muscles and transferred this core muscle activation into everyday life activities. Improved bodily confidence covered narratives of being more certain of the ability to control their bodies. Easier and safer activities showed how they could now perform activities in everyday life more safely and easily. Increased independence and participation involved the participants' improved ability and self-confidence to execute activities by themselves, as well as their increased participation in activities in daily living. Experiences of the balance exercise programme revealed that they found the programme novel and challenging. The overall theme was balance exercise facilitates everyday life.

    CONCLUSION: Participating in the CoDuSe programme was perceived to facilitate everyday life for people with multiple sclerosis. Taking part in the balance exercise programme taught the participants how to activate and use the core muscles, which increased their bodily confidence. Having increased bodily confidence helped them to perform everyday life activities with more ease and safety, which increased their independence and participation. The participants described the CoDuSe programme as novel and challenging, yet feasible.

    Place, publisher, year, edition, pages
    John Wiley & Sons, 2018
    Keywords
    Exercise, multiple sclerosis, postural balance, qualitative research
    National Category
    Occupational Therapy Other Health Sciences
    Research subject
    Disability Science
    Identifiers
    urn:nbn:se:oru:diva-68373 (URN)10.1002/pri.1728 (DOI)000447159800008 ()29962013 (PubMedID)2-s2.0-85050613048 (Scopus ID)
    Funder
    Swedish Research Council
    Note

    Funding Agencies:

    Norrbacka-Eugenia Foundation

    Uppsala-Örebro Regional Research Committee

    Available from: 2018-08-07 Created: 2018-08-07 Last updated: 2018-11-19Bibliographically approved
    4. Making it work: experience of living with a person who falls due to multiple sclerosis
    Open this publication in new window or tab >>Making it work: experience of living with a person who falls due to multiple sclerosis
    (English)Manuscript (preprint) (Other academic)
    National Category
    General Practice
    Identifiers
    urn:nbn:se:oru:diva-70253 (URN)
    Available from: 2018-11-19 Created: 2018-11-19 Last updated: 2018-11-19Bibliographically approved
  • Kucner, Tomasz Piotr
    Örebro University, School of Science and Technology.
    Probabilistic Mapping of Spatial Motion Patterns for Mobile Robots2018Doctoral thesis, monograph (Other academic)
    Abstract [en]

    To bring robots closer to real-world autonomy, it is necessary to equip them with tools allowing them to perceive, model and behave adequately to dynamic changes in the environment. The idea of incorporating information about dynamics not only in the robots reactive behaviours but also in global planning process stems from the fact that dynamic changes are typically not completely random and follow spatiotemporal patterns. The overarching idea behind the work presented in this thesis is to investigate methods allowing to represent the variety of the real-world spatial motion patterns in a compact, yet expressive way. The primary focus of the presented work is on building maps capturing the motion patterns of dynamic objects and/or the flow of continuous media.

    The contribution of this thesis is twofold. First, I introduce Conditional-Transition Map: a representation for modelling motion patterns of dynamic objects as a multimodal flow of occupancy over a grid map. Furthermore, in this thesis I also propose an extension (Temporal Conditional-Transition Map), which models the speed of said flow. The proposed representations connect the changes of occupancy among adjacent cells. Namely, they build conditional models of the direction to where occupancy is heading given the direction from which the occupancy arrived. Previously, all of the representations modelling dynamics in grid maps assumed cell independence. The representations assuming cell independence are substantially less expressive and store only information about the observed levels of dynamics (i.e. how frequent changes are at a certain location). In contrast, the proposed representations also encode information about the direction of motion. Furthermore, the multimodal and conditional character of the representations allows to distinguish and correctly model intersecting flows. The capabilities of the introduced grid-based representations are demonstrated with experiments performed on real-world data sets.

    In the second part of this thesis, I introduce Circular Linear Flow Field map modelling flow of continuous media and discrete objects. This representation, in contrast to the work presented in the first part of this thesis, does not model occupancy changes directly. Instead, it employs a field of Gaussian Mixture Models, whose local elements are probability distributions of (instantaneous) velocities, to describe motion patterns. Since it assumes only velocity measurements, the proposed representation have been used to model a broad spectrum of dynamics including motion patterns of people and airflow. Using a Gaussian Mixture Model allows to capture the multimodal character of real-world dynamics (e.g. intersecting flows) and also to account for flow variability. In addition to the basic learning algorithms, I present solutions (sampling-based and kernel-based approach) for the problem of building a dense Circular Linear Flow Field map using spatially sparse but temporally dense sets of measurements. In the end, I present how to use the Circular Linear Flow Field map in motion planning to achieve flow compliant trajectories. The capabilities of Circular Linear Flow Field maps are presented and evaluated using simulated and real-world datasets.

    The spectrum of applications for the representations and approaches presented in this thesis is very broad. Among others, the results of this thesis can be used by service robots providing help for passengers in crowded airports or drones surveying landfills to detect leakages of greenhouse gases. In the case of a service robot interacting with passengers in a populated airport, the information about the flow of passengers allows to build not only the shortest path between points “A” and “B” but also enables the robot to behave seamlessly, unobtrusively and safely. In the case of a drone patrolling a landfill the impact of airflow, is equally significant. In this scenario, information about airflow allows harnessing the energy of airstreams to lower the energy consumption of a drone. Another way to utilise information about the wind flow is to use it to improve localisation of sources of gas leakage.

  • Alirezaie, Marjan
    et al.
    Örebro University, School of Science and Technology.
    Hammar, Karl
    SICS - East Swedish ICT, Linköping, Sweden; Jönköping University, Jönköping, Sweden.
    Blomqvist, Eva
    SICS - East Swedish ICT, Linköping, Sweden.
    SmartEnv as a network of ontology patterns2018In: Semantic Web, ISSN 1570-0844, E-ISSN 2210-4968, Vol. 9, no 6, p. 903-918Article in journal (Refereed)
    Abstract [en]

    In this article we outline the details of an ontology, called SmartEnv, proposed as a representational model to assist the development process of smart (i.e., sensorized) environments. The SmartEnv ontology is described in terms of its modules representing different aspects including physical and conceptual aspects of a smart environment. We propose the use of the Ontology Design Pattern (ODP) paradigm in order to modularize our proposed solution, while at the same time avoiding strong dependencies between the modules in order to manage the representational complexity of the ontology. The ODP paradigm and related methodologies enable incremental construction of ontologies by first creating and then linking small modules. Most modules (patterns) of the SmartEnv ontology are inspired by, and aligned with, the Semantic Sensor Network (SSN) ontology, however with extra interlinks to provide further precision and cover more representational aspects.

    The result is a network of 8 ontology patterns together forming a generic representation for a smart environment. The patterns have been submitted to the ODP portal and are available on-line at stable URIs.

  • Lilliedahl, Jonathan
    Örebro University, School of Music, Theatre and Art. Högskolan för lärande och kommunikation, Högskolan i Jönköping, Jönköping, Sverige.
    Teoribaserad utvärdering av lämplighetsbedömning: Rapport från försöksverksamhet med lämplighetsbedömning vid antagning till lärar- och förskollärarutbildning2017Report (Other academic)
    Abstract [sv]

    Föreliggande rapport är en utvärdering av den försöksverksamhet med lämplighetsbedömning vid antagning till lärar- och förskollärarutbildning som bedrivits vid Jönköping University på uppdrag av Universitets- och högskolerådet.

    Försöksverksamheten har varit baserad på ett särskilt regeringsbeslut grundat i antaganden om lämplighetsbedömningens mening och eventuella effekter. Därför är denna utvärdering teoribaserad, det vill säga att den utgår från antaganden om lämplighetsbedömningens funktion givet en viss verksamhetslogik.

    Utvärderingen är genomförd på lokal nivå av undertecknad och i nära anslutning till genomförd lämplighetsbedömning. Underlaget består främst av inblandade parters upplevelser i kombination med utfall under ansökningsförfarandet. Sammantaget kombineras processutvärderande delar med mer effektutvärderande resonemang. En mer omfattande utvärdering kommer att genomföras av ansvarig myndighet, Universitets- och högskolerådet.

    Resultat talar för att krav på visad lämplighet kan ha effekter på sökandes agerande under ansöknings- och antagningsfaser. Lämplighetsbedömningen har först och främst fungerat som ett prov på sökande motivation för att bli antagen till utbildningen. Kravet som sådant – att sökande måste uppvisat lämplighet för behörighet till utbildningen – har förmodligen haft störst effekt, även om behållningen av självbedömning och andra aspekter inte bör underskattas.

    Välkommen att läsa utvärderingen i sin helhet för en mer utvecklad redogörelse av ovanstående.

  • Lilliedahl, Jonathan
    School of Education and Communication, Jönköping University, Jönköping, Sweden.
    The recontextualisation of knowledge: towards a social realist approach to curriculum and didactics2015In: Nordic Journal of Studies in Educational Policy, ISSN 2002-0317, Vol. 1, no 1, p. 40-47Article in journal (Refereed)
    Abstract [en]

    This article examines the relationship of curriculum and didactics through a social realist lens. Curriculum and didactics are viewed as linked and integrated by the common issue of educational content. The author argues that the selection of educational content and its organisation is a matter of recontextualising principles and that curriculum and didactics may be understood as interrelated stages of such recontextualisation. Educational policy and the organisation of pedagogic practice are considered as distinct although closely related practices of ‘curricularisation’ and ‘pedagogisation’. Neo-Bernsteinian social realism implies a sociological approach by which educational knowledge is recognised as something socially constructed, but irreducible to power struggles in policy arenas. More precisely, curriculum and didactics are not only matters of extrinsic standpoints. Recontextualising practices may also involve intrinsic features, that is, some kind of relatively generative logics that regulate curriculum design as well as pedagogic practice. In order to highlight certain implications for both curriculum and didactic theory, the author develops a typology that is analytically framed by principles of extrinsic relations to and intrinsic relations within curriculum or didactics.

  • Lilliedahl, Jonathan
    et al.
    Högskolan för lärande och kommunikation, Högskolan i Jönköping, Jönköping, Sverige.
    Sundberg, Daniel
    Institutionen för utbildningsvetenskap, Linnéuniversitetet, Växjö, Sverige.
    Wahlström, Ninni
    Institutionen för utbildningsvetenskap, Linnéuniversitetet, Växjö, Sverige.
    Teoribaserad utvärdering som svar på det tidiga 2000-talets frågor om utbildningsreformer2016In: Pedagogisk forskning i Sverige, ISSN 1401-6788, E-ISSN 2001-3345, Vol. 21, no 1-2, p. 9-29Article in journal (Refereed)
    Abstract [en]

    Theory-based evaluation in response to the issues of education reforms in the early 2000s

    The current surge of interest in evidence based policy has re-actualised issues of research, policy and pedagogic practice. Research are expected to support the development of systematically substantiated reforms as well as evidence-based practices. At the same time, criticism has been brought against dominant evaluation models. The question is whether they really respond to an increasingly complex landscape of governance, and the varying conditions and variations that characterize today’s schools? This article examines the potential of a theory-based evaluation model in order to systematically and empirically investigate education reforms. This approach provides the ability to include analysis of how transnational, national and local discourses converge and diverge in relation to each other, to take different kinds of contexts into consideration, and how these contexts affect the recontextualisation of pedagogic discourse. In order to further develop the approach of a theory-based evaluation, the authors point to recent steps within mixed methods research in relation to the design of, and findings in an empirical case study of the Swedish curriculum reform, Curriculum for the compulsory school, preschool class and the recreation centre, Lgr 11. Based on policy analyses, four hypotheses are presented: (i) the hypothesis of reform; (ii) the hypothesis of teachers’ professional practice; (iii) the hypothesis of teaching repertoires; (iv) and the hypothesis of assessment practices. Each of these hypotheses has been followed up by questionnaire responses and interviews.  The sequential explanatory design in this study relates critically transnational policy arenas to national education reforms and pedagogic practice in order to test the weight of the empirical evidence obtained. On the grounds of conclusion, there are reasons to revive and further develop the tradition of theory-based evaluations. Therefore, the article put forward theoretical and methodological proposals for the continued direction.

  • Georgii-Hemming, Eva
    et al.
    Örebro University, School of Music, Theatre and Art.
    Lilliedahl, Jonathan
    Jönköping University, Jönköping, Sweden.
    Why "What" Matters: On the Content Dimension of Music Didactics2014In: Philosophy of Music Education Review, ISSN 1063-5734, E-ISSN 1543-3412, Vol. 22, no 2, p. 132-155Article in journal (Refereed)
    Abstract [en]

    Is the most important function of education to provide students with basic skills and useful knowledge in order to eventually become employable? In many parts of the world knowledge league tables and policy documents inform us this is the case. As the question of what should form the educational content seems to be answered, teachers can concentrate on how they should teach, and researchers can concentrate on what method is the most effective. In the current rhetoric, however, many vital pedagogical issues have been placed in the background and the aesthetic subjects are downgraded. These tendencies worried Frede V. Nielsen who stated that didactic studies and philosophical inquiries yet again are needed to explore and give substance to the content dimension. Nielsen's writings on didactics form the basis for this essay, where we highlight which perspectives and dilemmas could be placed on a critical, philosophical didactic study agenda. The starting point is the field of tension between the what and the why of education.

  • Canelhas, Daniel Ricão
    et al.
    Univrses AB, Strängnäs, Sweden.
    Stoyanov, Todor
    Örebro University, School of Science and Technology.
    Lilienthal, Achim J.
    Örebro University, School of Science and Technology.
    A Survey of Voxel Interpolation Methods and an Evaluation of Their Impact on Volumetric Map-Based Visual Odometry2018In: Proceedings of the IEEE International Conference on Robotics and Automation (ICRA),, IEEE Computer Society, 2018, p. 6337-6343Conference paper (Refereed)
    Abstract [en]

    Voxel volumes are simple to implement and lend themselves to many of the tools and algorithms available for 2D images. However, the additional dimension of voxels may be costly to manage in memory when mapping large spaces at high resolutions. While lowering the resolution and using interpolation is common work-around, in the literature we often find that authors either use trilinear interpolation or nearest neighbors and rarely any of the intermediate options. This paper presents a survey of geometric interpolation methods for voxel-based map representations. In particular we study the truncated signed distance field (TSDF) and the impact of using fewer than 8 samples to perform interpolation within a depth-camera pose tracking and mapping scenario. We find that lowering the number of samples fetched to perform the interpolation results in performance similar to the commonly used trilinear interpolation method, but leads to higher framerates. We also report that lower bit-depth generally leads to performance degradation, though not as much as may be expected, with voxels containing as few as 3 bits sometimes resulting in adequate estimation of camera trajectories.

  • Köckemann, Uwe
    et al.
    Örebro University, School of Science and Technology.
    Alirezaie, Marjan
    Örebro University, School of Science and Technology.
    Karlsson, Lars
    Örebro University, School of Science and Technology.
    Loutfi, Amy
    Örebro University, School of Science and Technology.
    Integrating Ontologies for Context-based Constraint-based Planning2018In: MRC 2018: Modelling and Reasoning in Context, 2018, p. 22-29Conference paper (Refereed)
    Abstract [en]

    We describe an approach for integrating ontologies with a constraint-based planner to compile configuration planning domains based on the current context. We consider two alternative approaches: The first one integrates SPARQL queries directly with the planner while the second one generates SPARQL queries dynamically from provided triples. The first approach offers the full freedom of the SPARQL query language, while the second offers a more dynamic way for the planner to influence queries based on what is currently relevant for the planner. We evaluate the approach based on how much redundancy is removed by “outsourcing” knowledge into the ontology compared to modeling it directly into the domain of the planner.

  • Söderman, Annika
    et al.
    Örebro University, School of Health Sciences.
    Östlund, Ulrika
    Centre for Collaborative Palliative Care, Faculty of Health and Life Sciences, Linnaeus University, Växjö, Sweden; Centre for Research & Development, Uppsala University/Region Gävleborg, Gävle, Sweden.
    Werkander Harstäde, Carina
    Centre for Collaborative Palliative Care, Faculty of Health and Life Sciences, Linnaeus University, Växjö, Sweden.
    Blomberg, Karin
    Örebro University, School of Health Sciences.
    The adaptation of the Dignity Care Intervention to a Swedish context2018In: Nordic Conference in Nursing Research - Methods and Networks for the future, 2018, 2018Conference paper (Other academic)
    Abstract [en]

    Background: The Dignity Care Intervention (DCI) was developed in Scotland by Johnston and co-workers for nurses in municipality care, to enhance dignity in persons with palliative care needs. DCI includes a questionnaire, examples of reflective questions and suggests care actions. DCI has been tested in Ireland, and is now adapted to Swedish.

    Objective: To translate and adapt the DCI to a Swedish palliative context.

    Method: The questionnaire was translated and adapted into Swedish and reviewed by an expert group, before validated in cognitive interviews (N=7) with older persons. To update evidence concerning care actions from a Swedish context, a review of Swedish research literature and interviews with older persons, relatives and health care professionals were carried out. This gathered knowledge has been integrated into the Swedish DCI (DCI-SWE) and a feasibility study now takes place in one municipality in home care, Sweden. Included nurses got repeated information and participated in a shorter DCI-education, and will use the DCI in their everyday work for three months. Follow-up interviews will be conducted and analysed with qualitative content analysis.

    Results: The Swedish version of the questionnaire was experienced relevant for older persons, and both the Swedish review and the interviews gave culturally relevant proposals about dignity care actions. Further, a feasibility study will contribute to the ongoing development of the Swedish DCI-version.

    Conclusion and implication for practice: Implementing DCI in Sweden can enhance dignity in persons with palliative care needs and facilitate for a person-centered care.

  • Söderman, Annika
    et al.
    Örebro University, School of Health Sciences.
    Östlund, Ulrika
    Centre for Collaborative Palliative Care, Faculty of Health and Life Sciences, Linnaeus University, Växjö, Sweden; Centre for Research & Development, Uppsala University/Region Gävleborg, Gävle, Sweden.
    Werkander Harstäde, Carina
    Centre for Collaborative Palliative Care, Faculty of Health and Life Sciences, Linnaeus University, Växjö, Sweden.
    Blomberg, Karin
    Örebro University, School of Health Sciences.
    Enhancing dignity in older persons in Sweden: adaptation of the Dignity Care Intervention2018In: 24th Nordic Congress of Gerontology, 2018Conference paper (Other academic)
    Abstract [en]

    Background : In end of life, the older persons´ experiences of dignity can be affected due to serious illness and life changes, derived from physical, psychological, social and existential dimension. Loss of dignity impact the persons´ will to live. The Dignity Care Intervention (DCI) was developed and tested in Scotland and Ireland, to enhance dignity of older persons with palliative care needs, by nurses in municipality care. DCI consists a patient dignity inventory, reflective questions and examples of evidence-based care actions.

    The aim was to develop and adapt the DCI to a Swedish context.

    Methods: The patient dignity inventory was overall accepted by older persons in home care, however some changes in the wording were performed. The Swedish care actions reflected mostly earlier care actions described in the original version. However some more care actions derived in some of the categories in the Swedish DCI (DCI-SWE) e.g. “social support”, and some less care actions derived for example in the category “aftermath concerns”.  In DCI-SWE general care actions like e.g. to show respect were concretized unlike the original DCI.

    Conclusions: The DCI-SWE has prospects to enhance older persons´ dignity, and is now tested in a feasibility study by twelve nurses in home care.

  • Söderman, Annika
    et al.
    Örebro University, School of Health Sciences.
    Östlund, Ulrika
    Uppsala University/Region Gävleborg, Gävle, Sweden.
    Werkander Harstäde, Carina
    Linnaeus University, Växjö, Sweden.
    Blomberg, Karin
    Örebro University, School of Health Sciences.
    En intervention för att bevara sköra äldre personers värdighet: utveckling och anpassning till en svensk kontext 2018In: Forskningen och utvecklingens dag, 2018, Örebro, 2018Conference paper (Other academic)
    Abstract [sv]

    Bakgrund: Utvärdering av palliativ vård i Sverige har visat att vården är ojämlik och att äldre personer får sämre palliativ vård. För att främja äldre personers livskvalitet den sista tiden i livet är bevarande av värdighet grundläggande. Förlust av värdighet kan innebära förtvivlan, en känsla av att vara en börda för andra och en önskan om att få dö, vanliga upplevelser hos sköra äldre personer. Konkreta arbetssätt behöver därför utvecklas för att bevara äldre personers värdighet, vilket idag saknas inom svensk palliativ vård. En värdighetsbevarande intervention (DCI) har utvecklats och prövats i Skottland och Irland. Interventionen består av ett formulär för kartläggning av värdighet, reflekterande frågor samt evidensbaserade vårdhandlingar.

    Syfte: Syftet var att utveckla och anpassa DCI till en svensk kontext.

    Metod: Utveckling och kulturanpassning skedde genom 1) översättning och anpassning av formuläret till svensk kontext via en expertpanel och via kognitiva intervjuer med äldre personer 2) identifiering av värdighetsbevarande vårdhandlingar relevanta för en svensk kontext, utifrån en litteraturgenomgång samt via intervjuer med äldre personer, deras närstående och vårdpersonal.

    Resultat: Mindre revideringar av formuläret genomfördes, men överlag accepterades det av de äldre personerna. Identifierade värdighetsbevarande vårdhandlingar speglade mestadels de redan angivna i originalversionen DCI. Dock framkom fler vårdhandlingar än i originalet vid några av kategorierna i den svenska DCI (DCI-SWE) som t.ex. ”socialt stöd”, medan det framkom färre vårdhandlingar än originalet vid t.ex. ”dödens följder för andra”. I DCI-SWE konkretiserades generella vårdhandlingar som t.ex. att lyssna och visa respekt, till skillnad från originalet.

    Konklusion: DCI-SWE har möjlighet att främja sköra äldre personers värdighet, och prövas nu av sjuksköterskor i en genomförbarhetsstudie inom hemsjukvården.

  • Björkvall, Anders
    Örebro University, School of Humanities, Education and Social Sciences.
    Det värdefulla skräpet: ”Upcycling” och värdeökningens semiotik2018In: Grammatik, kritik, didaktik: Nordiska studier i systemisk-funktionell lingvistik och socialsemiotik / [ed] Inga-Lill Grahn, Hans Landqvist, Benjamin Lyngfelt, Andreas Nord, Lena Rogström, Barbro Wallgren Hemlin, Göteborg: Göteborgs universitet, 2018, Vol. 34, p. 55-77Chapter in book (Refereed)
  • Ekström, Cecilia
    Örebro University, Örebro University School of Business.
    Enabling and Coercive Control: Coexistence in the Case of Banking2018Doctoral thesis, monograph (Other academic)
    Abstract [en]

    This thesis focuses on subjects of control and attitudinal outcomes of formalized control in organizations. Previous research have concluded contradicting results of whether formalized control is positive or negative for the employees and propose that not only degree of formalization, but also type of formalization, can explain attitudinal outcomes.

    With the theoretical perspective of Adler and Borys’ concepts of enabling and coercive types of control, this thesis explore the concepts and practices of enabling and coercive control, and their relationships with attitudinal outcomes. This is done with a focus on the banking industry, which serve as a case of an extensively regulated context. An assumption put forth in this thesis is that the context in which individuals are part must be considered in the study of attitudinal outcomes of control.

    The analysis show that both enabling and coercive control can be found in banking, for example in business plans and regulations. However, the picture emerging is more complex than enabling control leading to positive attitudes, and coercive control leading to negative attitudes. Also, coexistence of enabling and coercive control is responded to with decoupling and acquiescence, and by drawing on global transparency.

    Based on these findings, together with theoretical elaborations, this thesis contribute to the literature of enabling and coercive control in a number of ways. First, it make explicit central concepts and relationships within the theory, such as design vs. perception, the role of zone of indifference as an outcome of control, and enabling and coercive control as dual roles or qual-ities of control. Moreover, this thesis suggests that multiple-level explanations to attitudinal outcomes of control, where contextual and institutional structures are considered, helps us understand attitudes to control in this context. Lastly, this thesis contribute to the notion of coexistence of enabling and coercive control by showing that coexistence can be simultaneous systems, and simultaneous cognitions, where a control can be perceived as both enabling and coercive at the same time.

  • Holmberg, John
    et al.
    Larsson, Jörgen
    Nässén, Jonas
    Svenberg, Sebastian
    Örebro University, School of Humanities, Education and Social Sciences.
    Andersson, David
    Low-carbon transitions and the good life2012Report (Other academic)
    Abstract [en]

    A transition to a low-carbon economy requires farreaching reductions in emissions, which in addition will have to take place at the same time as the global population is growing. A growing population also makes ever greater demands on welfare, while the ecological, social and economic systems that have to sustain this development are already under severe strain. It is commonly argued that emission reductions in a growing world economy can and should be achieved by technical innovations so that the transition to a low-carbon economy does not imply a negative impact on human well-being.

    This report discusses whether there might perhaps be another way of understanding the situation. Is the presumed linkage between well-being and climate impact always negative? Could a greater focus on human well-being be a driver of, rather than an obstacle to, sustainable development? This report attempts to identify possible strategies to support both [the good life] and decreased emissions. By adopting this research approach, the authors aim to make a contribution to the discussion of low-carbon transitions in society.

  • Svenberg, Sebastian
    Örebro University, School of Humanities, Education and Social Sciences.
    Sent på jorden2017In: Röda rummet, ISSN 1403–3844, Vol. 173-174, no 1-2, p. 10-11Article, book review (Other (popular science, discussion, etc.))
  • Svenberg, Sebastian
    et al.
    Örebro University, School of Humanities, Education and Social Sciences.
    Elam, Mark
    Department of Sociology and Work Science, University of Gothenburg, Gothenburg, Sweden.
    Swedish Nuclear Waste Management on the Move: From the Finnish Uptake of KBS-3 to the Rise of SKB International2014Report (Other academic)
  • Svenberg, Sebastian
    Örebro University, School of Humanities, Education and Social Sciences.
    Social ontologi2017In: Salongen - Nettidsskrift for filosofi og idehistorieArticle in journal (Other (popular science, discussion, etc.))
  • Svenberg, Sebastian
    Örebro University, School of Humanities, Education and Social Sciences.
    Expanding conjunctions and climate change2016In: AcclimatizeArticle in journal (Other (popular science, discussion, etc.))
  • Thunberg, Sara
    Örebro University, School of Law, Psychology and Social Work.
    Victimization, Positioning, and Support2018In: En forskningskonferens kring föräldraskap och föräldra-barnrelationen, 2018Conference paper (Other academic)