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Stamatiou, Georgios
Publikasjoner (10 av 35) Visa alla publikasjoner
Sympa, P., Vlachou, E., Kazakos, K., Govina, O., Stamatiou, G. & Lavdaniti, M. (2018). Depression and Self-Efficacy in Patients with Type 2 Diabetes in Northern Greece. Endocrine, Metabolic & Immune Disorders - Drug Targets, 18(4), 371-378
Åpne denne publikasjonen i ny fane eller vindu >>Depression and Self-Efficacy in Patients with Type 2 Diabetes in Northern Greece
Vise andre…
2018 (engelsk)Inngår i: Endocrine, Metabolic & Immune Disorders - Drug Targets, ISSN 1871-5303, E-ISSN 2212-3873, Vol. 18, nr 4, s. 371-378Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Background: Depression represents one of the most common disorders in diabetic patients and frequently complicates the health care of this population. Poor self-efficacy has been associated with increased depressive symptoms as well as poor glycemic control.

Objective: To assess depression and self-efficacy in adults with type 2 diabetes in Northern Greece and to explore the factors which may affect them in this group of population.

Method: A descriptive study was conducted in a tertiary hospital in the largest city of Northern Greece. The study group included a convenience sample of 170 adults with type 2 diabetes mellitus who completed the General Health Questionnaire-28 (GHQ-28) and the Diabetes Empowerment Scale- short form (DES) questionnaire.

Results: The overall rate of diabetic patients showing psychological distress in the present study was 50.6%. Adults with low and moderate income experienced higher levels of depression and anxiety, compared to those with high economical status (p<0,001). Also, adults who graduated elementary education experienced higher levels of depressive and anxiety symptoms than those with a higher educational level (p =0,038). There was a statistically significant difference between age (p<0.001), type of residence (p=0.019), family status (p=0,002), financial status (p<0.001) and self-efficacy. Also, there was a negative correlation between BMI and self-efficacy (r=-0.206, p<0.001) and a negative correlation between depression and self-efficacy scale (r=-0.439, p<0.001)

Conclusion: The results of the present study highlight the importance of well-planned interventions in order to reduce depression and increase self-efficacy in diabetic adults and to help them further improve their quality of life.

sted, utgiver, år, opplag, sider
Bentham Science Publishers, 2018
Emneord
Depression, anxiety, distress, self-efficacy, diabetes mellitus, Greece
HSV kategori
Identifikatorer
urn:nbn:se:oru:diva-82027 (URN)10.2174/1871530317666171120154002 (DOI)000435434400012 ()29165096 (PubMedID)2-s2.0-85048974084 (Scopus ID)
Tilgjengelig fra: 2020-05-26 Laget: 2020-05-26 Sist oppdatert: 2020-05-26bibliografisk kontrollert
Saridou, E., Stamatiou, G. & Lavdaniti, M. (2016). The Usage of Benzodiazepines in Primary Health Care Practice. In: : . Paper presented at 43rd Panhellenic Nurses Congress, Ermoupoli, Syros, Greece, May 11-14, 2016.
Åpne denne publikasjonen i ny fane eller vindu >>The Usage of Benzodiazepines in Primary Health Care Practice
2016 (engelsk)Konferansepaper, Poster (with or without abstract) (Annet vitenskapelig)
HSV kategori
Identifikatorer
urn:nbn:se:oru:diva-82842 (URN)
Konferanse
43rd Panhellenic Nurses Congress, Ermoupoli, Syros, Greece, May 11-14, 2016
Tilgjengelig fra: 2020-06-09 Laget: 2020-06-09 Sist oppdatert: 2020-06-09bibliografisk kontrollert
Kyrodimos, E., Stamatiou, G., Margaritis, E., Kikidis, D. & Sismanis, A. (2014). Cartilage tympanoplasty: a reliable technique for smokers. European Archives of Oto-Rhino-Laryngology, 271(2), 255-260
Åpne denne publikasjonen i ny fane eller vindu >>Cartilage tympanoplasty: a reliable technique for smokers
Vise andre…
2014 (engelsk)Inngår i: European Archives of Oto-Rhino-Laryngology, ISSN 0937-4477, E-ISSN 1434-4726, Vol. 271, nr 2, s. 255-260Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The aim of this study was to report our experience with cartilage tympanoplasty (CT) in smokers and compare it with that of non-smokers using a retrospective chart review at a tertiary referral center. Between September 2008 and September 2010, cartilage tympanoplasty was performed in 52 patients. Among them, 27 were active smokers and 25 former or non-smokers. The entire tympanic membrane was replaced with conchal cartilage, shaped either as a shield for cases with intact canal wall mastoidectomies, or crashed for cases with canal wall down procedures. The mean post-operative follow-up was 12 months (range 6-18 months). A complete pre- and post-operative audiologic evaluation was obtained in all patients. Graft take was successful in all patients. The overall average pre-operative and post-operative pure tone average air-bone gaps (PTA-ABG) was 52.2 dB +/- A 17.7 dB and 35.4 dB +/- A 17.9 dB, respectively, with an overall improvement of 16.8 dB (p < 0.001). A post-operative PTA-ABG of 25 dB or less was achieved in 39 (75 %) patients (p < 0.001). In smokers, the hearing improvement was 17.6 dB (p < 0.001) with a PTA-ABG of 25 dB or less in 19 (70 %). In non-smokers, the average hearing improvement was 16.8 dB (p < 0.0005) with a post-operative PTA-ABG of 25 dB or less in 19 (76 %), (p < 0.001). The results showed that the CT technique is a very effective procedure for smokers. Excellent graft take and satisfactory hearing results can be accomplished regardless of smoking habits.

sted, utgiver, år, opplag, sider
Springer, 2014
Emneord
Cartilage tympanoplasty, Otologic surgery, Smokers, Graft take, Hearing results
HSV kategori
Identifikatorer
urn:nbn:se:oru:diva-82344 (URN)10.1007/s00405-013-2410-7 (DOI)000329996400006 ()23440436 (PubMedID)2-s2.0-84899119018 (Scopus ID)
Tilgjengelig fra: 2020-06-03 Laget: 2020-06-03 Sist oppdatert: 2020-06-03bibliografisk kontrollert
Stamatiou, G. & Stankovic, K. M. (2013). A Comprehensive Network and Pathway Analysis of Human Deafness Genes. Otology and Neurotology, 34(5), 961-970
Åpne denne publikasjonen i ny fane eller vindu >>A Comprehensive Network and Pathway Analysis of Human Deafness Genes
2013 (engelsk)Inngår i: Otology and Neurotology, ISSN 1531-7129, E-ISSN 1537-4505, Vol. 34, nr 5, s. 961-970Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Objective: To perform comprehensive network and pathway analyses of the genes known to cause genetic hearing loss.

Study Design: In silico analysis of deafness genes using ingenuity pathway analysis (IPA).

Methods: Genes relevant for hearing and deafness were identified through PubMed literature searches and the Hereditary Hearing Loss Homepage. The genes were assembled into 3 groups: 63 genes that cause nonsyndromic deafness, 107 genes that cause nonsyndromic or syndromic sensorineural deafness, and 112 genes associated with otic capsule development and malformations. Each group of genes was analyzed using IPA to discover the most interconnected, that is, "nodal" molecules, within the most statistically significant networks (p < 10(-45)).

Results: The number of networks that met our criterion for significance was 1 for Group 1 and 2 for Groups 2 and 3. Nodal molecules of these networks were as follows: transforming growth factor beta1 (TGFB1) for Group 1, MAPK3/MAPK1 MAP kinase (ERK 1/2) and the G protein coupled receptors (GPCR) for Group 2, and TGFB1 and hepatocyte nuclear factor 4 alpha (HNF4A) for Group 3. The nodal molecules included not only those known to be associated with deafness (GPCR), or with predisposition to otosclerosis (TGFB1), but also novel genes that have not been described in the cochlea (HNF4A) and signaling kinases (ERK 1/2).

Conclusion: A number of molecules that are likely to be key mediators of genetic hearing loss were identified through three different network and pathway analyses. The molecules included new candidate genes for deafness. Therapies targeting these molecules may be useful to treat deafness.

sted, utgiver, år, opplag, sider
Lippincott Williams & Wilkins, 2013
Emneord
Deafness genes, ERK 1/2, GPCR, HNF4A, MAPK1, Molecular pathways analysis, TGFB1
HSV kategori
Identifikatorer
urn:nbn:se:oru:diva-82030 (URN)10.1097/MAO.0b013e3182898272 (DOI)000330371400032 ()23770690 (PubMedID)2-s2.0-84880897755 (Scopus ID)
Merknad

Funding Agencies:

United States Department of Health & Human Services

National Institutes of Health (NIH) - USA

NIH National Institute on Deafness & Other Communication Disorders (NIDCD)

K08 DC010419

Bertarelli Foundation 

Tilgjengelig fra: 2020-05-26 Laget: 2020-05-26 Sist oppdatert: 2020-05-26bibliografisk kontrollert
Stamatiou, G. (2013). Cochlear Ototoxicity: a temporal bone histopathology study. (Licentiate dissertation). University College London Ear Institute
Åpne denne publikasjonen i ny fane eller vindu >>Cochlear Ototoxicity: a temporal bone histopathology study
2013 (engelsk)Licentiatavhandling, med artikler (Annet vitenskapelig)
sted, utgiver, år, opplag, sider
University College London Ear Institute, 2013
HSV kategori
Identifikatorer
urn:nbn:se:oru:diva-83066 (URN)
Tilgjengelig fra: 2020-06-12 Laget: 2020-06-12 Sist oppdatert: 2020-06-12bibliografisk kontrollert
Kikidis, D. & Stamatiou, G. (2012). Common Mistakes during Neuro-otological Examination. Hellenic Otorhinolaryngology - Head and Neck Surgery, 33(1), 59-64
Åpne denne publikasjonen i ny fane eller vindu >>Common Mistakes during Neuro-otological Examination
2012 (nygresk (etter 1453))Inngår i: Hellenic Otorhinolaryngology - Head and Neck Surgery, ISSN 1791-2660, Vol. 33, nr 1, s. 59-64Artikkel i tidsskrift (Fagfellevurdert) Published
HSV kategori
Identifikatorer
urn:nbn:se:oru:diva-82350 (URN)
Tilgjengelig fra: 2020-06-03 Laget: 2020-06-03 Sist oppdatert: 2020-06-03bibliografisk kontrollert
Stamatiou, G. (2012). Contribution of Vestibular Evoked Myogenic Potentials (VEMP Test) to the Evaluation of Patients with Idiopathic Sudden Hearing Loss. (Doctoral dissertation). National & Kapodistrian University of Athens
Åpne denne publikasjonen i ny fane eller vindu >>Contribution of Vestibular Evoked Myogenic Potentials (VEMP Test) to the Evaluation of Patients with Idiopathic Sudden Hearing Loss
2012 (engelsk)Doktoravhandling, med artikler (Annet vitenskapelig)
Abstract [en]

Objective: To evaluate Vestibular Evoked Myogenic Potentials (VEMP) testing results in patients with unilateral Idiopathic Sudden Hearing Loss (ISHL) and to correlate them with the findings of caloric testing, the clinical appearance of vertigo, the influence of age, the grade and type of initial hearing loss and finally, the early recovery of subjects.Materials and

Methods: One hundred and four (104) patients with unilateral ISHL and 35 healthy controls were subjected to a standard protocol of neurotological evaluation. VEMP responses were measured and compared to caloric responses, to epidemiological and clinical parameters and to the initial and final audiograms of each subject. Results: Overall, abnormal VEMP responses were observed on the affected side in 28.8% of patients whereas abnormal Caloric findings occurred in 50% of the subjects studied. A significant relationship was found between the results of the two tests, meaning that the highest probability is either of the lesion to spare both otoliths and semicircular canals or, to involve both labyrinthic structures at the same time. A significant relationship was found between the type of vestibular lesion and subjective vertigo. Advancing age correlated statistically with more extended labyrinthic lesion, mostly including both semicircular canals and otolithic organs. Moreover, a statistically significant relationship was found between the type of inner ear lesion and the incidence of profound hearing loss. The type of vestibular lesion did not correlate with the occurrence of high frequency hearing loss, and the audiogram type had no significant effect on the likelihood of hearing recovery. Finally, a negative correlation was found between the extent of inner ear lesion and the likelihood of early recovery.

Conclusions: The combination of VEMP and ENG testing has proven vestibular involvement in many ISHL patients. Both tests are necessary in order to obtain a more thorough and deep knowledge of the pathophysiology of ISHL. The extent of inner-ear lesion tends to correlate with the severity of cochlear damage in ISHL. Vestibular assessment can be extremely valuable in prediction of the final outcome.

sted, utgiver, år, opplag, sider
National & Kapodistrian University of Athens, 2012
HSV kategori
Identifikatorer
urn:nbn:se:oru:diva-83064 (URN)
Tilgjengelig fra: 2020-06-12 Laget: 2020-06-12 Sist oppdatert: 2020-06-12bibliografisk kontrollert
Stamatiou, G. & Stankovic, K. M. (2012). Molecular Pathway Analysis of Genetic Hearing Loss. In: : . Paper presented at 145th Annual Spring Meeting at COSM, American Otological Society (AOS) Section, San Diego, CA, USA, April 21-22, 2012 (pp. 43-43).
Åpne denne publikasjonen i ny fane eller vindu >>Molecular Pathway Analysis of Genetic Hearing Loss
2012 (engelsk)Konferansepaper, Poster (with or without abstract) (Annet vitenskapelig)
Abstract [en]

Hypothesis: Deafrress genes are intercoonected through common molecular pathways.

Background: There are many genes implicated in genetic hearing loss, and many more to be identified. This daunting complexity can be simplified by analyzing molecular pathways that these genes belong to.

Methods: Genes relevant for hearing and deaftress were identified through PubMed literature searches, and assembled into 3 groups: (1) 74 genes that cause non-syndromic deafress, (2) 125 genes that cause non-syndromic and syndromic deafress, and (3) 122 getes associated with otic capsule development and malformations. Each group was analyzed using lngenuity Pathway Analysis to discover the most interconnected ,i.e. 'nodal' molecules, within the most statistically sipificant networks (p<10-45).

Results: The number of networks that met our criterion for significance was I (group l) or 2 (groups 2 and 3). Nodal molecules of these networks were: Transforming Growth Factor Betal (TGFBI) for group 1, p42/p44 MAP Kinase (ERK l/2) and the G Protein Coupled Receptors (GPCR) for group 2, and TGFBI and Hepatocyte Nuclear Factor 4 alpha (HNF4a) for group 3. The nodal molecules included not only those known to be associated with deaftress (GPCR), or with predisposition to otosclerosis (TGFB I ), but also novel genes that have not been described in the cochlea (HNF4a), and signaling kinases (ERK l/2).

Conclusions: A number of molecules that are likely to be key mediators of genetic hearing loss were identified through three different molecular pathway analyses. The molecules included new candidate genes for deafress. Therapies targeting these molecules may be useful to treat deahess.

HSV kategori
Identifikatorer
urn:nbn:se:oru:diva-82825 (URN)
Konferanse
145th Annual Spring Meeting at COSM, American Otological Society (AOS) Section, San Diego, CA, USA, April 21-22, 2012
Tilgjengelig fra: 2020-06-09 Laget: 2020-06-09 Sist oppdatert: 2020-06-09bibliografisk kontrollert
Stamatiou, G., Kyrodimos, E. & Sismanis, A. (2011). Complications of Cochlear Implantation in Adults. Paper presented at Joint Meeting of the 4th Consensus in Auditory Implants/5th European-Academy-of-Otology-and-Neuro-Otology (EAONO) Instructional Workshop, Parma, Italy, June 16-19, 2010. Annals of Otology, Rhinology and Laryngology, 120(7), 428-432
Åpne denne publikasjonen i ny fane eller vindu >>Complications of Cochlear Implantation in Adults
2011 (engelsk)Inngår i: Annals of Otology, Rhinology and Laryngology, ISSN 0003-4894, E-ISSN 1943-572X, Vol. 120, nr 7, s. 428-432Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Objectives: We describe our experience of intraoperative and postoperative complications of cochlear implantation in an adult population.

Methods: Between April 1986 and June 2010, the senior author (A.S.) performed 449 cochlear implantations in two different institutions. Of these, 212 implantations were in adults. The operative techniques were similar in all cases.

Results: Complications were observed in 12 of the 212 adult cases (5.7%), of which 10 were major (4.7%) and 2 minor (1%). In 7 cases, reimplantation was necessitated by device failure (6 cases; 2.8%) or device extrusion (I case; 0.5%). In 2 elderly patients (1%), a minor dural injury with a cerebrospinal fluid leak was controlled during the operation with temporalis fascia grafting. In 1 patient (0.5%), a subdural hematoma was observed after bipolar cauterization of a prominent diploic vein. In 2 subjects (1%), a wound infection was noted soon after implantation and was treated successfully on an outpatient basis.

Conclusions: Cochlear implantation is generally a safe procedure. The most common complication was device failure. Although complications in this adult population were rather uncommon, some of them were serious, and an immediate intervention was necessary for a successful outcome.

sted, utgiver, år, opplag, sider
Sage Publications, 2011
Emneord
adult, cochlear implantation, complication
HSV kategori
Identifikatorer
urn:nbn:se:oru:diva-82028 (URN)10.1177/000348941112000702 (DOI)000292951500002 ()21859050 (PubMedID)2-s2.0-79960199313 (Scopus ID)
Konferanse
Joint Meeting of the 4th Consensus in Auditory Implants/5th European-Academy-of-Otology-and-Neuro-Otology (EAONO) Instructional Workshop, Parma, Italy, June 16-19, 2010
Tilgjengelig fra: 2020-05-26 Laget: 2020-05-26 Sist oppdatert: 2020-05-26bibliografisk kontrollert
Stamatiou, G. & Bibas, A. (2011). Histopathological Findings of Cis-platinum Ototoxicity. In: : . Paper presented at 16th Panhellenic Congress of Otorhinolaryngology, Head and Neck Surgery, Athens, Greece, December 1-4, 2011.
Åpne denne publikasjonen i ny fane eller vindu >>Histopathological Findings of Cis-platinum Ototoxicity
2011 (engelsk)Konferansepaper, Poster (with or without abstract) (Annet vitenskapelig)
HSV kategori
Identifikatorer
urn:nbn:se:oru:diva-82843 (URN)
Konferanse
16th Panhellenic Congress of Otorhinolaryngology, Head and Neck Surgery, Athens, Greece, December 1-4, 2011
Tilgjengelig fra: 2020-06-09 Laget: 2020-06-09 Sist oppdatert: 2020-06-09bibliografisk kontrollert
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