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Colins, O. F., Fanti, K. A., Hellfeldt, K., Frogner, L. & Andershed, H. (2025). Developmental trajectories of conduct problems from childhood to adolescence: Early childhood antecedents and outcomes in adolescence. Development and psychopathology (Print)
Open this publication in new window or tab >>Developmental trajectories of conduct problems from childhood to adolescence: Early childhood antecedents and outcomes in adolescence
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2025 (English)In: Development and psychopathology (Print), ISSN 0954-5794, E-ISSN 1469-2198Article in journal (Refereed) Epub ahead of print
Abstract [en]

Children and adolescents display varying trajectories of conduct problems (CP), but it is unclear if these CP trajectories can be distinguished by childhood antecedents and adolescent outcomes. Therefore, we tested if child- and environmental-level risk factors predict CP trajectory membership and if CP trajectories are associated with developmental outcomes in adolescence. Six waves of data (teacher-, parent- and child self-reports) were used from 2,045 children. General growth mixture modeling identified four CP trajectories (waves 2-5): childhood-persistent, childhood-limited, adolescent-onset, and low CP. Relative to the adolescent-onset CP trajectory, wave 1 child- and environmental-level risk factors increased the likelihood of being in the childhood-persistent CP trajectory, though all but two (callous-unemotional traits and non-intact family) antecedents lost significance after controlling for wave 1 conduct problems. Few significant differences emerged in risk factors when comparing childhood-persistent and childhood-limited CP trajectories. Individuals identified in the adolescent-onset and childhood-persistent CP trajectories faced a higher risk for later maladjustment than those in the childhood-limited CP trajectory, whereas the adolescent-onset and childhood-persistent CP trajectories only differed in three out of 13 outcomes. Overall, findings indicate that individuals with CP are at risk for later maladjustment, but predicting the childhood-persistent trajectory of CP in young children is difficult.

Place, publisher, year, edition, pages
Cambridge University Press, 2025
Keywords
Adolescent outcomes, antecedents, conduct problems, cumulative risk, developmental trajectories
National Category
Psychiatry Psychology (Excluding Applied Psychology)
Identifiers
urn:nbn:se:oru:diva-119384 (URN)10.1017/S0954579424001949 (DOI)001426266600001 ()39973160 (PubMedID)2-s2.0-85218770652 (Scopus ID)
Funder
Forte, Swedish Research Council for Health, Working Life and Welfare, 2023-01050Swedish Research Council, 2023-01468; 2007-2440
Available from: 2025-02-21 Created: 2025-02-21 Last updated: 2025-03-12Bibliographically approved
Fanti, K. A., Mavrommatis, I., Díaz-Vázquez, B., López-Romero, L., Romero, E., Álvarez-Voces, M., . . . Thomson, N. (2024). Fearlessness as an Underlying Mechanism Leading to Conduct Problems: Testing the INTERFEAR Model in a Community Sample in Spain. Children, 11(5), Article ID 546.
Open this publication in new window or tab >>Fearlessness as an Underlying Mechanism Leading to Conduct Problems: Testing the INTERFEAR Model in a Community Sample in Spain
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2024 (English)In: Children, E-ISSN 2227-9067, Vol. 11, no 5, article id 546Article in journal (Refereed) Published
Abstract [en]

Conduct problems (CP) in childhood and adolescence have a significant impact on the individual, family, and community. To improve treatment for CP, there is a need to improve the understanding of the developmental pathways leading to CP in boys and girls. Prior research has linked the child's fearlessness and callous-unemotional (CU) traits, as well as experiences of parental warmth and punitive parenting, to CP. However, few studies have tested the interplay of these factors in contributing to future CP development. The present study aimed to test the InterFear model, which suggests that fearlessness in early childhood leads to CP through an indirect pathway involving low positive parenting, high negative/punitive parenting, and callous-unemotional (CU) traits. The sample included 2467 Spanish children (48.1% girls; Mage = 4.25; SD = 0.91), followed up across a five-year period. Besides a direct association between fearlessness in early childhood and future CP, the results found an indirect pathway whereby fearlessness reduces positive parenting and increases punitive parenting, which contributes to the development of CU traits and sets the stage for CP in later childhood. The specific indirect effect from fearlessness to CP via CU traits accounted for most of the variance, suggesting the existence of a temperamental pathway independent of parental variables. Further, two additional indirect pathways, exclusive of fearlessness, were identified, which started with low parental warmth and positive parenting, leading to CP via CU traits. These findings support the InterFear model, demonstrating multiple pathways to CP with the involvement of fearlessness, parenting practices, and CU traits. This model might play a pivotal role in the development of targeted prevention and intervention strategies for CP.

Place, publisher, year, edition, pages
MDPI, 2024
Keywords
Callous–unemotional traits, conduct problems, fearlessness, parenting
National Category
Psychology (excluding Applied Psychology)
Identifiers
urn:nbn:se:oru:diva-113873 (URN)10.3390/children11050546 (DOI)001232640600001 ()38790541 (PubMedID)2-s2.0-85193956311 (Scopus ID)
Note

This study was supported by the Projects PID2019-107897RB-I00/funded by MICIU/AEI/10.13039/501100011033, and TED2021-130824B-C22, funded by MICIU/AEI/10.13039/501100011033 and the EU “NextGenerationEU”/PRTR. In addition, this study was supported by two grants from the University Teacher Training Program (MAV: FPU21/00552, and BDV: FPU22/02200), funded by MICIU/AEI/10.13039/501100011033 and FSE+, and the grant RYC2021-032890-I (LLR), funded by MICIU/AEI/10.13039/501100011033 and the EU “NextGenerationEU”/PRTR.

Available from: 2024-05-27 Created: 2024-05-27 Last updated: 2024-06-11Bibliographically approved
López-Romero, L., Andershed, H., Romero, E. & Cervin, M. (2024). In Search of Conceptual Clarity About the Structure of Psychopathic Traits in Children: A Network-Based Proposal. Child Psychiatry and Human Development
Open this publication in new window or tab >>In Search of Conceptual Clarity About the Structure of Psychopathic Traits in Children: A Network-Based Proposal
2024 (English)In: Child Psychiatry and Human Development, ISSN 0009-398X, E-ISSN 1573-3327Article in journal (Refereed) Epub ahead of print
Abstract [en]

Psychopathic traits in childhood have been revealed as potential identifiers of risk, being predictive of later forms of behavioral maladjustment. Yet, it is still under debate how psychopathic traits in children should be best conceptualized and which are the core dimensions for construct definition and prediction. The present study aims to examine the structure of psychopathic traits in childhood, and its predictive value, by using a combination of traditional factor analysis and more recent network-based methods. Data on psychopathic traits, as measured by the Child Problematic Traits Inventory (CPTI), were collected in a large sample of children (n = 2454; 48.2% girls), aged 3 to 6 at the onset of the study (Mage = 4.26; SD = 0.91), who were followed-up one and two years later using parent- and teacher-reports. Results showed that psychopathic traits measured via CPTI are best conceptualized as five latent factors encompassing grandiosity, deceitfulness, callousness, impulsivity and need of stimulation, a result that converged across informants and time. Callousness and grandiosity emerged as central traits using network analysis of parent-reports, while deceitfulness was most central using teacher-reports. Finally, callousness, impulsivity and deceitfulness emerged as the best predictors of concurrent, prospective and stable conduct problems. These results provide a refined structure of psychopathic traits in children that better accounts for the core elements of the construct. Additional theoretical and practical implications will be discussed in terms of assessment, diagnostic classification and tailored prevention/intervention.

Place, publisher, year, edition, pages
Springer, 2024
Keywords
Children, Conduct problems, Network structure, Prediction, Psychopathic traits
National Category
Psychiatry
Identifiers
urn:nbn:se:oru:diva-111026 (URN)10.1007/s10578-023-01649-z (DOI)001143932600001 ()38236454 (PubMedID)2-s2.0-85182241679 (Scopus ID)
Note

Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This study is part of the I + D + i Project PID2019-107897RB-I00/ funded by MCIN/AEI/https://doi.org/10.13039/501100011033, and it was supported by TED2021-130824B-C22, funded by MCIN/AEI/https://doi.org/10.13039/501100011033 and the European Union (EU) “NextGenerationEU”/PRTR. L. López-Romero’s contribution was supported by the grant RYC2021-032890-I, funded by MCIN/AEI/https://doi.org/10.13039/501100011033 and the European Union “NextGenerationEU”/PRTR.

Available from: 2024-01-30 Created: 2024-01-30 Last updated: 2024-02-05Bibliographically approved
Colins, O. F., López-Romero, L., Romero, E. & Andershed, H. (2024). The Prognostic Usefulness of Multiple Specifiers for Subtyping Conduct Problems in Early Childhood. Journal of the American Academy of Child and Adolescent Psychiatry, 63(4), 443-453
Open this publication in new window or tab >>The Prognostic Usefulness of Multiple Specifiers for Subtyping Conduct Problems in Early Childhood
2024 (English)In: Journal of the American Academy of Child and Adolescent Psychiatry, ISSN 0890-8567, E-ISSN 1527-5418, Vol. 63, no 4, p. 443-453Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To better describe and treat children with conduct problems (CP), grandiose-manipulative and daring-impulsive traits are proposed for subtyping CP, instead of using only a callous-unemotional specifier. However, the acclaimed benefits of having multiple specifiers for CP remain largely untested and therefore highly speculative. To fill this gap, this study tested longitudinal relations between these 3 specifiers and developmental outcomes in childhood and adolescence, independent of early childhood CP.

METHOD: Longitudinal data from 2 community studies were used. Teacher ratings were used to measure CP and the specifiers in 3- to 5-year-olds from Sweden (n = 2,064) and Spain (n = 2,055). Developmental outcomes were assessed by multiple informants (ie, teachers, parents, and children) 1 to 8 years later. RESULTS: Early childhood CP were predictive of all outcomes. Callous-unemotional traits predicted low levels of social competence and prosocial behavior, independent of CP (and age, gender, and socioeconomic status). Grandiose-manipulative and daring-impulsive traits were predictive of aggression and violent delinquency, respectively, independent of CP, but also of higher levels of prosocial behavior or social competence.

CONCLUSION: The 3 specifiers are predictive of different outcomes, independent of CP, which is thought to form the basis for developing specifiers for CP. Findings tentatively challenge the centrality of callous-unemotional traits for subtyping CP, but it is premature to conclude that grandiose-manipulative and daring-impulsive specifiers are needed in future revisions of DSM and ICD. Efforts to systematically evaluate the utility of these specifiers should be welcomed to inform ongoing debates on this matter.

Place, publisher, year, edition, pages
Elsevier, 2024
Keywords
Callous-unemotional, conduct problems, daring-impulsive, grandiose-manipulative, limited prosocial emotions
National Category
Psychology (excluding Applied Psychology)
Identifiers
urn:nbn:se:oru:diva-107461 (URN)10.1016/j.jaac.2023.05.022 (DOI)001224261700001 ()37442204 (PubMedID)2-s2.0-85169779961 (Scopus ID)
Funder
Swedish Research Council, 2007-2440Örebro UniversityKarlstad University
Note

Swedish Study: Waves 1-3 of the SOFIA study were funded by a grant from the Swedish Research Council (#2007-2440) . Waves 4 and 5 were funded by Örebro University with support from Karlstad municipality and Karlstad University. Spanish Study: This study was supported by projects PID2019-107897RB-I00, funded by MCIN/AEI/10.13039/501100011033, and TED2021-130824B-C22, funded by MCIN/AEI/10.13039/501100011033, and the European Union (EU) NextGenerationEU/PRTR. Laura Lopez-Romero 's contribution was supported by grant RYC2021-032890-I, funded by MCIN/AEI/10.13039/501100011033 and the NextGenerationEU/PRTR. The writing of the manuscript was also supported by a Fonds Wetenschappelijk Onderzoek (FWO) Odysseus Grant (G0H7818N) and an FWO Research Project (G007720N) awarded to Olivier F. Colins.

Available from: 2023-08-09 Created: 2023-08-09 Last updated: 2024-06-04Bibliographically approved
Garcia, M., Rouchy, E., Colins, O., Andershed, H. & Michel, G. (2024). Validation of the French Youth Psychopathic Traits Inventory-Short Version in a general population sample of emerging adults in France. Psychologie Francaise, 69(1), 67-83
Open this publication in new window or tab >>Validation of the French Youth Psychopathic Traits Inventory-Short Version in a general population sample of emerging adults in France
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2024 (English)In: Psychologie Francaise, ISSN 0033-2984, E-ISSN 1873-7277, Vol. 69, no 1, p. 67-83Article in journal (Refereed) Published
Abstract [en]

Introduction: The Youth Psychopathic Traits Inventory (YPI) is one of the most commonly used scales for measuring psychopathic traits from childhood to adulthood.

Objective: The aim of the current research was to scrutinize the psychometric properties of the Youth Psychopathic Traits Inventory-Short Version (YPI-S) translated into French.

Method: The factor structure, internal consistency, and convergent validity of YPI-S scores were examined in a sample of 757 emerging adults from the general population in France (aged 18–20 years; 54.43% women).

Results: Results of confirmatory factor analyses support the proposed 3-factor structure (observed in children and adolescents) among both men and women. The YPI-S total score and the 3 factor (Grandiose-Manipulative, Callous-Unemotional, and Impulsive-Irresponsible) scores were internally consistent. Correlations with external criterion variables of interest, including the Dark Triad construct and its components (psychopathy, machiavellianism and narcissism), reactive and proactive aggression, and delinquency, support the convergent validity of the interpretation of YPI-S scores. Finally, findings also suggest that YPI-S works consistently for both men and women.

Conclusion: In addition to demonstrating the psychometric qualities of the French version of the YPI-S, this research provides further evidences for the value of this brief and time-effective self-report instrument in the study of psychopathic traits across different developmental phases, and especially during the transition to adulthood. 

Place, publisher, year, edition, pages
Elsevier, 2024
Keywords
Psychopathic traits, YPI-S, Psychometric, Emerging adults, Gender, Callous-unemotional, Traits psychopathiques, Propriétés psychométriques, Jeunes adultes, Genre, Traits Callous-unemotional
National Category
Psychiatry Psychology
Identifiers
urn:nbn:se:oru:diva-99606 (URN)10.1016/j.psfr.2022.04.004 (DOI)001203016700001 ()2-s2.0-85131432793 (Scopus ID)
Available from: 2022-06-15 Created: 2022-06-15 Last updated: 2024-04-30Bibliographically approved
Demetriou, C. A., Colins, O. F., Andershed, H. & Fanti, K. A. (2023). Assessing Psychopathic Traits Early in Development: Testing Potential Associations with Social, Behavioral, and Affective Factors. Journal of Psychopathology and Behavioral Assessment, 45(3), 767-780
Open this publication in new window or tab >>Assessing Psychopathic Traits Early in Development: Testing Potential Associations with Social, Behavioral, and Affective Factors
2023 (English)In: Journal of Psychopathology and Behavioral Assessment, ISSN 0882-2689, E-ISSN 1573-3505, Vol. 45, no 3, p. 767-780Article in journal (Refereed) Published
Abstract [en]

The Child Problematic Traits Inventory (CPTI) enables the assessment of psychopathy dimensions as early as age three. The current study employs a multi-informant approach (i.e., fathers, mothers, and teachers) to further investigate the unique associations between psychopathy dimensions, as measured by the CPTI, with theoretically relevant constructs of interest, such as conduct problems, oppositionality, empathy, and social relations, in early childhood (N = 1283, M age = 6.35). Although associations with conduct, aggressive, and oppositional behaviours differed in strength, our findings supported the importance of all psychopathy dimensions in predicting behavioral problems. Our findings also suggested a unique association of the callous-unemotional dimension with affective empathy. Furthermore, stronger associations were identified between the callous-unemotional and impulsive need for stimulation dimensions with social problems (e.g., peer and family relations) compared to the grandiose-deceitful dimension. Current findings can inform prevention and intervention efforts aiming to alter the development of psychopathic traits.

Place, publisher, year, edition, pages
Springer, 2023
Keywords
Callous-unemotional traits, Impulsive need for stimulation, Grandiose-deceitful, Conduct problems, Empathy, Parenting
National Category
Psychology
Identifiers
urn:nbn:se:oru:diva-106820 (URN)10.1007/s10862-023-10059-3 (DOI)001007624900001 ()2-s2.0-85161912970 (Scopus ID)
Available from: 2023-07-28 Created: 2023-07-28 Last updated: 2023-11-16Bibliographically approved
Solares, C., Zhang, L., Chang, Z., Andershed, H., Persson, J. & Larsson, H. (2023). Externalizing Behaviors and Alzheimer's Disease and Any Dementia: A Multigeneration Cohort Study in Sweden. Innovation in Aging, 7(9), Article ID igad117.
Open this publication in new window or tab >>Externalizing Behaviors and Alzheimer's Disease and Any Dementia: A Multigeneration Cohort Study in Sweden
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2023 (English)In: Innovation in Aging, E-ISSN 2399-5300, Vol. 7, no 9, article id igad117Article in journal (Refereed) Published
Abstract [en]

BACKGROUND AND OBJECTIVES: We examined the extent to which externalizing behaviors such as violent and nonviolent criminal behavior, and substance use disorders (SUD) are associate with the onset of Alzheimer's disease (AD) and any dementia in prior generations.

RESEARCH DESIGN AND METHODS: A nationwide cohort of 2,463,033 individuals born between 1973 and 1997 (index persons) were linked to their biological relatives (parents, grandparents, and uncles/aunts) using Swedish national registers. Cox regression models were used to examine the association between each measure of externalizing behaviors with AD and any dementia in each of the relative cohorts.

RESULTS: Parents of index persons with externalizing behaviors had an increased risk for AD compared with parents of index persons without externalizing behaviors-nonviolent criminal behavior: Hazard Ratio (HR) = 1.16, 95% Confidence Intervals (CI) 1.10-1.22; violent criminal behavior: HR = 1.32 (95% CI: 1.19-1.45); SUD: HR = 1.28 (95% CI: 1.17, 1.40). The associations attenuated with decreasing familial relatedness. Relatives of individuals with externalizing behaviors compared with relatives of individuals without, showed an increased risk of having both early-onset and late-onset AD but the strength of the associations was higher for early-onset AD than for late-onset AD. A similar pattern of results was observed for the association with any dementia.

DISCUSSION AND IMPLICATIONS: Externalizing behaviors are associated with AD and any dementia in prior generations. The associations were stronger for parents in comparison with grandparents and uncles/aunts, suggesting shared familial risks between conditions. This warrants further studies examining common genetic and family-wide environmental factors that may contribute to identifying common underlying mechanisms to the development of externalizing behaviors, AD, and any dementia.

Place, publisher, year, edition, pages
Oxford University Press, 2023
Keywords
Criminal behavior, Epidemiology, Family design, Major neurodegenerative disorders, Substance abuse
National Category
Neurosciences
Identifiers
urn:nbn:se:oru:diva-109961 (URN)10.1093/geroni/igad117 (DOI)001106048000002 ()38024330 (PubMedID)2-s2.0-85178100452 (Scopus ID)
Funder
EU, Horizon 2020, 754285Swedish Research Council, 2018-02599; 2018-02213; 2021-06370The Swedish Brain Foundation, FO2021-0115
Available from: 2023-11-30 Created: 2023-11-30 Last updated: 2024-02-26Bibliographically approved
Fanti, K. A., Mavrommatis, I., Colins, O. & Andershed, H. (2023). Fearlessness as an Underlying Mechanism Leading to Conduct Problems: Testing the Intermediate Effects of Parenting, Anxiety, and callous-unemotional Traits. Research on child and adolescent psychopathology, 51(8), 1115-1128
Open this publication in new window or tab >>Fearlessness as an Underlying Mechanism Leading to Conduct Problems: Testing the Intermediate Effects of Parenting, Anxiety, and callous-unemotional Traits
2023 (English)In: Research on child and adolescent psychopathology, ISSN 2730-7166, Vol. 51, no 8, p. 1115-1128Article in journal (Refereed) Published
Abstract [en]

This study investigates whether the longitudinal association between fearlessness and conduct problems (CP) is mediated by warm and harsh parenting, parent-child conflict, anxiety, and callous-unemotional (CU) traits. The constructs under investigation were assessed at five different time points, spanning a period of eight years. A multi-informant approach was followed, collecting data from parents and teachers (N = 2,121; 47% girls). The structural equation model pointed to both direct and indirect pathways between fearlessness and CP. Specifically, findings suggested that Time 1 fearlessness (age 3-5 years) increased the likelihood of Time 2 (age 4-6 years) harsh parenting and Time 3 (age 5-7 years) parent-child conflict. Further, fearlessness was positively associated with Time 4 (age 8-10) callous-unemotional traits and Time 5 (age 11-13) CP. The total indirect effect from fearlessness to CP through these variables was significant, although the specific indirect effect from fearlessness to CU traits to CP accounted for most of the variance. Warm parenting and anxiety did not mediate the association between fearlessness and CP. In addition to the identified pathways connecting fearlessness to CP, findings pointed to the existence of multiple developmental pathways to future CP, as well as gender differences in longitudinal associations.

Place, publisher, year, edition, pages
Springer, 2023
Keywords
Callous unemotional traits, Conduct problems, Fearlessness, Parent-child conflict, Parenting
National Category
Psychology (excluding Applied Psychology)
Identifiers
urn:nbn:se:oru:diva-105973 (URN)10.1007/s10802-023-01076-7 (DOI)000988420800001 ()37191864 (PubMedID)2-s2.0-85159467534 (Scopus ID)
Available from: 2023-05-17 Created: 2023-05-17 Last updated: 2023-11-16Bibliographically approved
Golovchanova, N., Evans, B., Hellfeldt, K., Andershed, H. & Boersma, K. (2023). Older and feeling unsafe? Differences in underlying vulnerability, anxiety and life satisfaction among older adults. Aging & Mental Health, 27(8), 1636-1643
Open this publication in new window or tab >>Older and feeling unsafe? Differences in underlying vulnerability, anxiety and life satisfaction among older adults
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2023 (English)In: Aging & Mental Health, ISSN 1360-7863, E-ISSN 1364-6915, Vol. 27, no 8, p. 1636-1643Article in journal (Refereed) Published
Abstract [en]

Objectives: Feeling safe in the daily environment is important in late life. However, research on configuration of vulnerability factors for perceived unsafety in older adults is scarce. The current study aimed to identify latent subgroups of older adults based on their vulnerability for perceived unsafety.

Method: We analyzed the data from a cross-sectional survey of residents in senior apartments in a mid-sized Swedish municipality (N = 622).

Results: The results of the latent profile analysis based on frailty, fear of falling, social support, perceived neighborhood problems, and trust in others in the neighborhood indicated the presence of three profiles. These profiles were labelled as compromised body and social networks (7.2%), compromised context (17.9%) and non-vulnerable (74.9%). Profile membership was statistically predicted by age, gender, and family status and profiles differed in perceived unsafety, anxiety and life satisfaction.

Conclusion: Overall, the study findings suggested the existence of latent subgroups of older people based on patterns of vulnerability.

Place, publisher, year, edition, pages
Routledge, 2023
Keywords
Feelings of unsafety, Quality of life/wellbeing, anxiety, environmental factors/housing/rural-urban factors, fear of crime, frailty, neighborhood, social support, well-being
National Category
Gerontology, specialising in Medical and Health Sciences
Identifiers
urn:nbn:se:oru:diva-104568 (URN)10.1080/13607863.2023.2177255 (DOI)000942315100001 ()36849364 (PubMedID)2-s2.0-85148999981 (Scopus ID)
Funder
European Commission, 754285
Available from: 2023-02-28 Created: 2023-02-28 Last updated: 2023-11-16Bibliographically approved
Solares, C., Garcia-Argibay, M., Chang, Z., Dobrosavljevic, M., Larsson, H. & Andershed, H. (2023). Risk of dementia and mild cognitive impairment in older adults with a criminal background: a population-based register study in Sweden. Scientific Reports, 13(1), Article ID 1915.
Open this publication in new window or tab >>Risk of dementia and mild cognitive impairment in older adults with a criminal background: a population-based register study in Sweden
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2023 (English)In: Scientific Reports, E-ISSN 2045-2322, Vol. 13, no 1, article id 1915Article in journal (Refereed) Published
Abstract [en]

Criminal behaviour has previously been associated with an increased risk for several mental health problems, but little is known about the association between criminal behaviour and dementia. We aimed to examine how the criminal background (type of crime, number of convictions, length of the sentence) is associated with dementia and mild cognitive impairment (MCI), and how mental and physical health disorders and educational attainment influenced these associations. A nationwide cohort of 3,617,028 individuals born between 1932 and 1962 were linked with criminal and medical records using Swedish national registers. We used Cox regression models to examine the associations. Increased risks for dementia (Hazard ratios (HRs) 1.54, 95% confidence interval (CI) 1.50-1.57) and MCI (1.55, 1.50-1.61) were found in individuals with criminal background, particularly among those who committed violent or several crimes, or with long sentences. After full adjustment of covariates, the associations attenuated but remained statistically significant for dementia (1.25, 1.22-1.28) and MCI (1.27, 1.22-1.32). The attenuation was mostly explained by mental health problems -depression, anxiety, schizophrenia spectrum disorders, substance use disorder (SUD), and bipolar disorder- (dementia: 1.34, 1.31-1.37; MCI: 1.35, 1.30-1.40). SUD contributed the most to attenuate the associations. Our results may provide important insights to health and penal systems by showing the importance of considering the severity of the criminal background and life-course mental health when assessing the risk of neurodegenerative disorders.

Place, publisher, year, edition, pages
Nature Publishing Group, 2023
National Category
Psychiatry Public Health, Global Health and Social Medicine
Identifiers
urn:nbn:se:oru:diva-104027 (URN)10.1038/s41598-023-28962-w (DOI)000985266900053 ()36732577 (PubMedID)2-s2.0-85147318448 (Scopus ID)
Funder
EU, Horizon 2020, 754285The Swedish Brain Foundation, FO2021-0115Swedish Research Council, 2018-02599 2018-02213
Available from: 2023-02-03 Created: 2023-02-03 Last updated: 2025-02-20Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0002-8163-6558

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