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Vikerfors, Anders
Publications (4 of 4) Show all publications
Carlsson, J., Vikerfors, A., Frey, J., Jerlström, T. & Davidsson, S. (2019). Is soluble PD-L1 a potential biomarker for urothelial bladder cancer?. In: : . Paper presented at Keystone Symposia Conference 2019: Cancer metastasis: The role of metabolism, immunity and the microenvironment, Florens, Italy, March 15-19, 2019.
Open this publication in new window or tab >>Is soluble PD-L1 a potential biomarker for urothelial bladder cancer?
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2019 (English)Conference paper, Oral presentation with published abstract (Refereed)
National Category
Cancer and Oncology
Identifiers
urn:nbn:se:oru:diva-73843 (URN)
Conference
Keystone Symposia Conference 2019: Cancer metastasis: The role of metabolism, immunity and the microenvironment, Florens, Italy, March 15-19, 2019
Available from: 2019-04-17 Created: 2019-04-17 Last updated: 2019-04-17Bibliographically approved
Böös, M., Jerlström, T., Beckman, E., Bläckberg, M., Brändstedt, J., Kollberg, P., . . . Liedberg, F. (2019). Who should record surgical complications?: Results from a third-party assessment of complications after radical cystectomy. Scandinavian journal of urology, 53(5), 339-343
Open this publication in new window or tab >>Who should record surgical complications?: Results from a third-party assessment of complications after radical cystectomy
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2019 (English)In: Scandinavian journal of urology, ISSN 2168-1805, E-ISSN 2168-1813, Vol. 53, no 5, p. 339-343Article in journal (Refereed) Published
Abstract [en]

Objective: In Sweden complications after radical cystectomy have been reported to the nationwide population-based Swedish Cystectomy Registry since 2011. Here, validation of the reporting was assessed in two healthcare regions.

Materials and methods: Complications were ascertained from patient records by a third party not involved in the care delivered to 429 randomly selected patients from 949 who had undergone radical cystectomy since 2011 in four hospitals. Without knowledge of the outcome in the primary registration, post-operative complications within 90 days post-operatively were assessed by an independent review of patient charts, and the results were compared with the primary reports in the Swedish Cystectomy Registry.

Results: The third-party assessment identified post-operative complications in 310 patients (72%). Low-grade complications (Clavien-Dindo I-II) were noted in 110 (26%) of the patients in the primary registration, but increased to 182 (42%) in the validation (p < 0.00001). High-grade complications (Clavien-Dindo III-V) were reported in 113 (26%) patients in the primary registration, but in 128 (30%) of the patients in the validation (p = 0.02). According to the third-party assessment, 18 patients (4%) had Clavien-Dindo grade IV complications and 12 (3%) died within 90 days of surgery (Clavien-Dindo grade V); corresponding values in the primary registration were 15 (3%) and 9 (2%), respectively. The readmission rate within 90 days increased from 27 to 32% in the validation (p < 0.00001).

Conclusions: Compared with registry data, third-party assessment revealed more complications and readmissions after radical cystectomy. Hence such evaluation may improve the validity of reported complication data.

Place, publisher, year, edition, pages
Informa Healthcare, 2019
Keywords
Clavien-Dindo, Third-party validation, bladder cancer, post-operative complications, radical cystectomy
National Category
Surgery Urology and Nephrology
Identifiers
urn:nbn:se:oru:diva-75818 (URN)10.1080/21681805.2019.1643912 (DOI)000480114400001 ()31385741 (PubMedID)
Funder
Swedish Cancer Society, 2017/278BioCARE - Biomarkers in Cancer Medicine Improving Health Care Education and Innovation
Note

Funding Agencies:

Lund Medical Faculty (ALF)  

Skåne University Hospital Research Funds  

Sten K. Johnson Foundation  

Krapperup Foundation  

Skåne County Council's Research and Development Foundation  REGSKANE-622351 

Gösta Jonsson Research Foundation  

Hillevi Fries Research Foundation 

Available from: 2019-08-23 Created: 2019-08-23 Last updated: 2019-12-19Bibliographically approved
Carlsson, J., Vikerfors, A., Frey, J., Jerlström, T. & Davidsson, S. (2019). Är nivåer av cirkulerande CD163 associerat med kliniska parametrar för urinblåsecancer?. Paper presented at Urologidagarna 2019, Västerås, Sweden, 2-4 October, 2019. Svensk Urologi, 3, 53-53
Open this publication in new window or tab >>Är nivåer av cirkulerande CD163 associerat med kliniska parametrar för urinblåsecancer?
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2019 (Swedish)In: Svensk Urologi, ISSN 2001-6794, Vol. 3, p. 53-53Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
Svensk Urologisk Förening, 2019
National Category
Cancer and Oncology
Identifiers
urn:nbn:se:oru:diva-77780 (URN)
Conference
Urologidagarna 2019, Västerås, Sweden, 2-4 October, 2019
Available from: 2019-11-05 Created: 2019-11-05 Last updated: 2020-01-28Bibliographically approved
Böös, M., Jerlström, T., Beckman, E., Bläckberg, M., Brändstedt, J., Kollberg, P., . . . Liedberg, F.Who should record surgical complications? Results from a third-party assessment of complications after radical cystectomy.
Open this publication in new window or tab >>Who should record surgical complications? Results from a third-party assessment of complications after radical cystectomy
Show others...
(English)Manuscript (preprint) (Other academic)
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-73418 (URN)
Available from: 2019-04-01 Created: 2019-04-01 Last updated: 2019-04-01Bibliographically approved
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