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Four treatment failures of pharyngeal gonorrhoea with ceftriaxone (500 mg) or cefotaxime (500 mg), Sweden, 2013 and 2014
World Health Organization Collaborating Centre for Gonorrhoea and other Sexually Transmitted Infections, Swedish Reference Laboratory for Pathogenic Neisseria, Department of Laboratory Medicine, Microbiology, Örebro University Hospital, Örebro, Sweden.
Dept Clin Microbiol, Karolinska Univ Hosp, Stockholm, Sweden.
Dept Clin Microbiol, Cent Hosp Växjö, Växjö, Sweden.
Dept Dermatovenereol, Karolinska Univ Hosp, Stockholm, Sweden.
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2014 (engelsk)Inngår i: Eurosurveillance, ISSN 1025-496X, E-ISSN 1560-7917, Vol. 19, nr 30, s. 2-5, artikkel-id 20862Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

We describe four cases in Sweden of verified treatment failures of pharyngeal gonorrhoea with ceftriaxone (500 mg; n=3) or cefotaxime (500 mg; n=1) monotherapy. All the ceftriaxone treatment failures were caused by the internationally spreading multidrug-resistant gonococcal NG-MAST genogroup 1407 clone. Increased awareness of treatment failures is crucial particularly when antimicrobial monotherapy is used. Frequent test of cure and appropriate verification/falsification of suspected treatment failures, as well as implementation of recommended dual antimicrobial therapy are imperative.

sted, utgiver, år, opplag, sider
European Centre for Disease Prevention and Control (ECDC) , 2014. Vol. 19, nr 30, s. 2-5, artikkel-id 20862
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URN: urn:nbn:se:oru:diva-56395ISI: 000341245000001Scopus ID: 2-s2.0-84928254092OAI: oai:DiVA.org:oru-56395DiVA, id: diva2:1082091
Tilgjengelig fra: 2017-03-15 Laget: 2017-03-15 Sist oppdatert: 2018-06-19bibliografisk kontrollert

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