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Diagnosis and management of microscopic colitis
Örebro universitet, Hälsoakademin.
Vise andre og tillknytning
2008 (engelsk)Inngår i: World Journal of Gastroenterology, ISSN 1007-9327, E-ISSN 2219-2840, Vol. 14, nr 48, s. 7280-7288Artikkel i tidsskrift (Annet vitenskapelig) Published
Abstract [en]

Microscopic colitis, comprising collagenous and lymphocytic colitis, is characterized clinically by chronic watery diarrhea, and a macroscopically normal colonic mucosa where diagnostic histopathological features are seen on microscopic examination. The annual incidence of each disorder is 4-6/100,000 inhabitants, with a peak incidence in 60-70-year-old individuals and a noticeable female predominance for collagenous colitis. The etiology is unknown. Chronic diarrhea, abdominal pain, weight loss, fatigue and fecal incontinence are common symptoms, which impair the health-related quality of life of the patient. There is an association with other autoimmune disorders such as celiac disease, diabetes mellitus, thyroid disorders and arthritis. Budesonide is the best-documented short-term treatment, but the optimal long-term strategy needs further study. The long-term prognosis is good and the risk of complications including colonic cancer is low.

sted, utgiver, år, opplag, sider
Beijing: WJG Press , 2008. Vol. 14, nr 48, s. 7280-7288
HSV kategori
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Invärtesmedicin
Identifikatorer
URN: urn:nbn:se:oru:diva-3799DOI: 10.3748/wjg.14.7280PubMedID: 19109861OAI: oai:DiVA.org:oru-3799DiVA, id: diva2:138097
Tilgjengelig fra: 2009-01-07 Laget: 2009-01-07 Sist oppdatert: 2017-12-14bibliografisk kontrollert

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Tysk, CurtBohr, JohanNyhlin, NilsWickbom, Anna

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