oru.sePublikasjoner
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Colonization pattern of coagulase-negative staphylococci in preterm neonates and the relation to bacteremia
Department of Pediatrics, Örebro University Hospital, Örebro, Sweden.
Department of Pediatrics, Örebro University Hospital, Örebro, Sweden.
Department of Clinical Microbiology, Örebro University Hospital, Örebro, Sweden.
Örebro universitet. Department of Pediatrics, Örebro University Hospital, Örebro, Sweden.
Vise andre og tillknytning
2010 (engelsk)Inngår i: European Journal of Clinical Microbiology and Infectious Diseases, ISSN 0934-9723, E-ISSN 1435-4373, Vol. 29, nr 9, s. 1085-1093Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Coagulase-negative staphylococci (CoNS) are the major cause of sepsis in extreme preterm (EPT) newborns, but data on the CoNS colonization in EPT newborns prior to invasive infection are limited. Our aim was to describe the early establishment of the CoNS microflora in EPT newborns and to compare the colonization pattern in neonates with and without positive CoNS blood cultures. From a cohort of 46 EPT neonates, newborns with positive CoNS blood culture were identified (n = 10) and compared with matched controls. Samples for bacterial cultures were obtained repetitively from nares, perineum, and umbilicus. All CoNS isolates were characterized using the PhenePlate system for biochemical fingerprinting. Persistent CoNS strains were found on day 2-3 after delivery in 7/20 newborns, and there was a tendency for earlier colonization in nares than in the perineum or umbilicus. The CoNS blood strains were prevalent in superficial sites prior to positive blood culture (11/14 blood strains), but no single invasive pathway was identified. Most CoNS blood strains (9/14) persisted on superficial sites after antibiotic treatment. We hypothesize that the invasive pathways in neonatal CoNS sepsis are complex and that the colonization of mucosal membranes and umbilical catheters might be of equal importance.

sted, utgiver, år, opplag, sider
Springer, 2010. Vol. 29, nr 9, s. 1085-1093
HSV kategori
Identifikatorer
URN: urn:nbn:se:oru:diva-25348DOI: 10.1007/s10096-010-0966-3ISI: 000280844500006PubMedID: 20517628Scopus ID: 2-s2.0-78349284429OAI: oai:DiVA.org:oru-25348DiVA, id: diva2:547123
Merknad

Funding Agency:

Research committee of Örebro county, Sweden

Tilgjengelig fra: 2012-08-27 Laget: 2012-08-27 Sist oppdatert: 2018-01-12bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekstPubMedScopus

Personposter BETA

Björkqvist, MariaSchollin, JensSöderquist, Bo

Søk i DiVA

Av forfatter/redaktør
Björkqvist, MariaSchollin, JensSöderquist, Bo
Av organisasjonen
I samme tidsskrift
European Journal of Clinical Microbiology and Infectious Diseases

Søk utenfor DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 520 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf