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Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994
Department of Social Research, University of Helsinki, Helsinki, Finland; Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country, Leioa, Spain.
Örebro universitet, Institutionen för juridik, psykologi och socialt arbete. Department of Psychology, University of Southern California, Los Angeles, United States.ORCID-id: 0000-0001-8768-6954
Department of Social Research, University of Helsinki, Helsinki, Finland; Osaka University Graduate School of Medicine, Osaka University, Osaka, Japan.
Antal upphovsmän: 992016 (Engelska)Ingår i: eLIFE, E-ISSN 2050-084X, Vol. 5, artikel-id e20320Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis of 40 twin cohorts including 143,390 complete twin pairs born 1886-1994. Although genetic variance showed a generally increasing trend across the birth-year cohorts, heritability estimates (0.69-0.84 in men and 0.53-0.78 in women) did not present any clear pattern of secular changes. Comparing geographic-cultural regions (Europe, North America and Australia, and East Asia), total height variance was greatest in North America and Australia and lowest in East Asia, but no clear pattern in the heritability estimates across the birth-year cohorts emerged. Our findings do not support the hypothesis that heritability of height is lower in populations with low living standards than in affluent populations, nor that heritability of height will increase within a population as living standards improve.

Ort, förlag, år, upplaga, sidor
Cambridge, United Kingdom: eLife Sciences Publications Ltd , 2016. Vol. 5, artikel-id e20320
Nationell ämneskategori
Evolutionsbiologi
Identifikatorer
URN: urn:nbn:se:oru:diva-55060DOI: 10.7554/eLife.20320ISI: 000391277600001PubMedID: 27964777Scopus ID: 2-s2.0-85006379669OAI: oai:DiVA.org:oru-55060DiVA, id: diva2:1069907
Anmärkning

Funding Agency:

Suomen Akatemia 266592

Tillgänglig från: 2017-01-30 Skapad: 2017-01-30 Senast uppdaterad: 2017-11-29Bibliografiskt granskad

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Tuvblad, Catherine

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