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An integrative approach for biological data mining and visualisation
VTT Technical Research Centre of Finland, Espoo, Finland.
VTT Technical Research Centre of Finland, Espoo, Finland.
VTT Technical Research Centre of Finland, Espoo, Finland.
VTT Technical Research Centre of Finland, Espoo, Finland.
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2008 (Engelska)Ingår i: International Journal of Data Mining and Bioinformatics, ISSN 1748-5673, E-ISSN 1748-5681, Vol. 2, nr 1, s. 54-77Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

The emergence of systems biology necessitates development of platforms to organise and interpret plentitude of biological data. We present a system to integrate data across multiple bioinformatics databases and enable mining across various conceptual levels of biological information. The results are represented as complex networks. Context dependent mining of these networks is achieved by use of distances. Our approach is demonstrated with three applications: full metabolic network retrieval with network topology study, exploration of properties and relationships of a set of selected proteins, and combined visualisation and exploration of gene expression data with related pathways and ontologies.

Ort, förlag, år, upplaga, sidor
Inderscience Publishers , 2008. Vol. 2, nr 1, s. 54-77
Nyckelord [en]
Data mining, bioinformatics, complex networks, heterogeneous database integration, systems biology
Nationell ämneskategori
Bioinformatik och systembiologi
Identifikatorer
URN: urn:nbn:se:oru:diva-70913DOI: 10.1504/IJDMB.2008.016756ISI: 000254468600004PubMedID: 18399328Scopus ID: 2-s2.0-39149116367OAI: oai:DiVA.org:oru-70913DiVA, id: diva2:1345886
Tillgänglig från: 2019-08-26 Skapad: 2019-08-26 Senast uppdaterad: 2019-09-05Bibliografiskt granskad

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