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Home sampling and pooling of vaginal samples are effective tools for genetic screening of Chlamydia trachomatis among high school female students in Lithuania
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2008 (Engelska)Ingår i: Scandinavian Journal of Infectious Diseases, ISSN 0036-5548, E-ISSN 1651-1980, Vol. 40, nr 2, s. 88-93Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

The aims were 1) to estimate the prevalence of C. trachomatis infection among sexually active female students in Kaunas, Lithuania; 2) to investigate the usefulness of personal invitation, self-sampling, and pooling of samples for screening; and 3) to evaluate the costs of the approaches used. A cross-sectional study inviting 795 female students (18–31 y of age) from 7 high schools and 1 college in Kaunas was performed. The response rate was 67% (533/795). Self-obtained vaginal samples were analysed, individually and pooled (n=3), using Digene Hybrid Capture II CT/NG Test. The overall prevalence of C. trachomatis infection was 5.6%. Among the sexually active female students 20–24 y of age (n=424), the prevalence was 7.1%; however, the prevalence varied from 0% to 14.2% at the different schools. For estimation of the population prevalence based solely on identification of C. trachomatis positive pools, the pooling strategy reduced the costs by 85%. For estimation of population prevalence and for diagnosis of each individual sample, pooling reduced the costs by 70%. Targeted screening, using pooling to reduce the expenses, mainly of 3rd and 4th y Lithuanian female students could be recommended. By extended personal contact and internet-based communication, increased participation rates may be attained.

Ort, förlag, år, upplaga, sidor
London: Taylor & Francis , 2008. Vol. 40, nr 2, s. 88-93
Nyckelord [en]
Adolescent, Adult, Chlamydia Infections/*diagnosis/epidemiology, Chlamydia trachomatis/genetics/isolation & purification, Cost-Benefit Analysis, Female, Humans, Lithuania/epidemiology, Mass Screening/*methods, Oligonucleotide Array Sequence Analysis, Prevalence, Self Care/*methods, Sexual Behavior, Specimen Handling, Students, Vaginal Diseases/*diagnosis/epidemiology/microbiology, Vaginal Smears/methods
Nationell ämneskategori
Medicin och hälsovetenskap Dermatologi och venereologi
Forskningsämne
Dermatologi och venereologi
Identifikatorer
URN: urn:nbn:se:oru:diva-3465DOI: 10.1080/00365540701587002PubMedID: 17852902OAI: oai:DiVA.org:oru-3465DiVA, id: diva2:137762
Tillgänglig från: 2008-12-08 Skapad: 2008-12-08 Senast uppdaterad: 2017-12-14Bibliografiskt granskad

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