Case-control study on occupational exposure to extremely low-frequency electromagnetic fields and glioma risk
2017 (English)In: American Journal of Industrial Medicine, ISSN 0271-3586, E-ISSN 1097-0274, Vol. 60, no 5, p. 494-503Article in journal (Refereed) Published
Abstract [en]
BACKGROUND: Exposure to extremely low-frequency electromagnetic fields (ELF-EMF) was in 2002 classified as a possible human carcinogen, Group 2B, by the International Agency for Research on Cancer at WHO.
METHODS: Life time occupations were assessed in case-control studies during 1997-2003 and 2007-2009. An ELF-EMF Job-Exposure Matrix was used for associating occupations with ELF exposure (μT). Cumulative exposure (μT-years), average exposure (μT), and maximum exposed job (μT) were calculated.
RESULTS: Cumulative exposure gave for astrocytoma grade IV (glioblastoma multiforme) in the time window 1-14 years odds ratio (OR) = 1.9, 95% confidence interval (CI) = 1.4-2.6, p linear trend <0.001, and in the time window 15+ years OR = 0.9, 95%CI = 0.6-1.3, p linear trend = 0.44 in the highest exposure categories 2.75+ and 6.59+ μT years, respectively.
CONCLUSION: An increased risk in late stage (promotion/progression) of astrocytoma grade IV for occupational ELF-EMF exposure was found.
Place, publisher, year, edition, pages
John Wiley & Sons, 2017. Vol. 60, no 5, p. 494-503
Keywords [en]
ELF-EMF, RF-EMF, astrocytoma, electromagnetic fields, glioma, occupational exposure, risk factors, wireless phones
National Category
Occupational Health and Environmental Health Cancer and Oncology
Identifiers
URN: urn:nbn:se:oru:diva-57328DOI: 10.1002/ajim.22707ISI: 000399609000010PubMedID: 28394434Scopus ID: 2-s2.0-85017463500OAI: oai:DiVA.org:oru-57328DiVA, id: diva2:1103662
Note
Funding agencies:
Kone Foundation Helsinki
Finland Cancer-och Allergifonden
Cancerhjälpen
Pandora-Foundation for Independent Research, Berlin, Germany
2017-05-302017-05-302020-08-27Bibliographically approved