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Generalised joint hypermobility and neurodevelopmental traits in a non-clinical adult population
Örebro University, School of Medical Sciences. Stockholm County Council, Stockholm, Sweden.
Örebro University, School of Medical Sciences. University Health Care Research Centre, Region Örebro County, Örebro, Sweden.ORCID iD: 0000-0002-3587-6075
Örebro University, School of Medical Sciences. University Health Care Research Centre, Region Örebro County, Örebro, Sweden.ORCID iD: 0000-0001-6726-7787
2017 (English)In: BJPsych Open, E-ISSN 2056-4724, Vol. 3, no 5, p. 236-242Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Generalised joint hypermobility (GJH) is reportedly overrepresented among clinical cases of attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD) and developmental coordination disorder (DCD). It is unknown if these associations are dimensional and, therefore, also relevant among non-clinical populations.

AIMS: To investigate if GJH correlates with sub-syndromal neurodevelopmental symptoms in a normal population.

METHOD: Hakim-Grahame's 5-part questionnaire (5PQ) on GJH, neuropsychiatric screening scales measuring ADHD and ASD traits, and a DCD-related question concerning clumsiness were distributed to a non-clinical, adult, Swedish population (n=1039).

RESULTS: In total, 887 individuals met our entry criteria. We found no associations between GJH and sub-syndromal symptoms of ADHD, ASD or DCD.

CONCLUSIONS: Although GJH is overrepresented in clinical cases with neurodevelopmental disorders, such an association seems absent in a normal population. Thus, if GJH serves as a biomarker cutting across diagnostic boundaries, this association is presumably limited to clinical populations.

Place, publisher, year, edition, pages
Royal College of Psychiatrists , 2017. Vol. 3, no 5, p. 236-242
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:oru:diva-62454DOI: 10.1192/bjpo.bp.116.004325ISI: 000418507300005PubMedID: 28959454OAI: oai:DiVA.org:oru-62454DiVA, id: diva2:1162495
Funder
Swedish Research Council, K2012-62X-22130-04-6The Karolinska Institutet's Research FoundationStockholm County CouncilAvailable from: 2017-12-04 Created: 2017-12-04 Last updated: 2020-01-23Bibliographically approved

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Glans, MartinBejerot, SusanneHumble, Mats B.

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