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Spatial variation in the effects of air pollution on cardiovascular mortality in Beijing, China
Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China; Center of Environmental and Health Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China; Center of Environmental and Health Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China; Center of Environmental and Health Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China; Center of Environmental and Health Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
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2019 (engelsk)Inngår i: Environmental science and pollution research international, ISSN 0944-1344, E-ISSN 1614-7499Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Due to lack of data from multiple air quality monitoring stations, studies about spatial association between concentrations of ambient pollutants and mortality in China are rare. To investigate the spatial variation of association between concentrations of particulate matter less than 10 μm in aerodynamic diameter (PM10) and nitrogen dioxide (NO2) and cardiovascular mortality in Beijing, China, we collected data including daily deaths, concentrations of PM10 and NO2, and meteorological factors from January 1, 2009, to December 31, 2010, in all 16 districts of Beijing. Generalized additive model (GAM) and generalized additive mixed model (GAMM) were used to examine the citywide and district-specific effects of PM10 and NO2 on cardiovascular mortality. The citywide effect derived from GAMM was lower than that derived from GAM and the strongest effects were identified for 2-day moving average lag 0–1. For every 10 μg/m3 increases in concentrations of PM10 and NO2, the corresponding daily cardiovascular mortality increases in 0.31% (95%CI 0.15%, 0.46%) and 1.63% (95%CI 1.11%, 2.13%), respectively. The death risk associated with air pollutants varied across different geographic districts in Beijing. We found spatially varied adverse effects of air pollution on cardiovascular deaths in Beijing. But there was insufficient evidence to show the significant spatial heterogeneity in mortality effects of PM10 and NO2 in this study.

sted, utgiver, år, opplag, sider
Springer, 2019.
Emneord [en]
Air pollution, Cardiovascular mortality, Generalized additive mixed model, Generalized additive model, Spatio-temporal analysis
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Identifikatorer
URN: urn:nbn:se:oru:diva-70344DOI: 10.1007/s11356-018-3725-0ISI: 000456198400038PubMedID: 30471063Scopus ID: 2-s2.0-85057181876OAI: oai:DiVA.org:oru-70344DiVA, id: diva2:1266047
Merknad

Funding Agencies:

Gong-Yi Program of the Chinese Ministry of Environmental Protection  200909016 

Peking Union Medical College Graduate Student Innovation Fund  

CAMS Innovation Fund for Medical Sciences  2017-I2M-1-009 

China Medical Board  15-230 

National Natural Science Foundation of China  41771435 

China Scholarship Council  201704910297 

Tilgjengelig fra: 2018-11-27 Laget: 2018-11-27 Sist oppdatert: 2019-02-07bibliografisk kontrollert

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