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Iron Deficiency Is Common During Remission in Children With Inflammatory Bowel Disease
Karlstad Central Hospital, Karlstad, Sweden.
Astrid Lindgren Children’s Hospital, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.
Karlstad Central Hospital, Karlstad, Sweden.
Karlstad Central Hospital, Karlstad, Sweden.
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2016 (English)In: Global pediatric health, ISSN 2333-794X, Vol. 3Article in journal (Refereed) Published
Abstract [en]

The aim was to study prevalence of iron deficiency in children with inflammatory bowel disease (IBD) during remission. In addition, there was an observational evaluation of hematological response to oral iron. A population-based retrospective study including 90 Swedish children (median 13 years) with IBD was performed. Patient records covered in median 25 months. Iron deficiency was present in 70/77 children (91%) in which iron status could be assessed. In clinical and biochemical remission, iron deficiency was found in 57/67 (85%) of children, and 23 (34%) of them had iron deficiency anemia. Thirty-six iron-deficient children were prescribed oral iron supplementation and 32 (89%) improved hemoglobin levels over 6 months. In conclusion, iron deficiency is common during clinical remission in children with IBD, even in cohorts with low prevalence of anemia. Therefore, regular biochemical screening for iron deficiency is warranted during all stages of disease, irrespective of symptoms and inflammatory blood markers.

Place, publisher, year, edition, pages
Sage Publications, 2016. Vol. 3
Keywords [en]
anemia, children, inflammatory bowel disease, iron deficiency, iron supplementation
National Category
Pediatrics Gastroenterology and Hepatology
Identifiers
URN: urn:nbn:se:oru:diva-74356DOI: 10.1177/2333794X16633672PubMedID: 27336004OAI: oai:DiVA.org:oru-74356DiVA, id: diva2:1317190
Available from: 2019-05-22 Created: 2019-05-22 Last updated: 2019-06-05Bibliographically approved

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Wikström, Sverre

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