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Beta-blocker Therapy is Associated with Decreased 1-year Mortality After Emergency Laparotomy in Geriatric Patients
Center for Trauma and Critical Care, Department of Surgery, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Örebro universitet, Institutionen för medicinska vetenskaper. Region Örebro län. (Clinical Epidemiology and Biostatistics)ORCID-id: 0000-0002-3552-9153
Örebro universitet, Institutionen för medicinska vetenskaper. Department of Surgery, Karolinska University Hospital, Stockholm, Sweden.
Division of Trauma and Emergency Surgery, Department of Surgery, Örebro University Hospital, Örebro, Sweden.
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2019 (Engelska)Ingår i: Scandinavian Journal of Surgery, ISSN 1457-4969, E-ISSN 1799-7267, artikel-id 1457496919877582Artikel i tidskrift (Refereegranskat) Epub ahead of print
Abstract [en]

BACKGROUND AND AIMS: Emergency laparotomy is associated with a great risk of mortality in the elderly. The hyperadrenergic state induced by surgical trauma may play an important role in the pathophysiology of this increased risk. Studies have shown that beta-blocker exposure may be associated with decreased morbidity and mortality in the perioperative period. We aimed to study the effect of beta-blocker on mortality in geriatric patients undergoing emergency laparotomy.

MATERIAL AND METHODS: ). The Poisson regression analysis was used to evaluate the association.

RESULTS:  = 0.004). No significant differences in the incidence of post-operative complications between the two groups could be measured.

CONCLUSION: Beta-blocker therapy may be associated with reduced 1-year mortality following emergency laparotomy in geriatric patients.

Ort, förlag, år, upplaga, sidor
Sage Publications, 2019. artikel-id 1457496919877582
Nyckelord [en]
Beta-blockers, emergency laparotomy, geriatrics, mortality
Nationell ämneskategori
Kardiologi
Identifikatorer
URN: urn:nbn:se:oru:diva-76831DOI: 10.1177/1457496919877582PubMedID: 31544597OAI: oai:DiVA.org:oru-76831DiVA, id: diva2:1355564
Tillgänglig från: 2019-09-30 Skapad: 2019-09-30 Senast uppdaterad: 2019-09-30Bibliografiskt granskad

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Cao, YangAhlstrand, RebeccaMohseni, Shahin

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Institutionen för medicinska vetenskaperRegion Örebro län
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Scandinavian Journal of Surgery
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