oru.sePublikationer
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Magnetic Resonance Imaging of the Heart: Image quality, measurement accuracy and patient experience
Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.ORCID-id: 0000-0001-5740-3538
2016 (Engelska)Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
Abstract [en]

Background: Non-invasive diagnostic imaging of atherosclerotic coronary artery disease (CAD) is frequently carried out with cardiovascular magnetic resonance imaging (CMR) or myocardial perfusion single photon emission computed tomography (MPS). CMR is the gold standard for the evaluation of scar after myocardial infarction and MPS the clinical gold standard for ischemia. Magnetic Resonance Imaging (MRI) is at times difficult for patients and may induce anxiety while patient experience of MPS is largely unknown.

Aims: To evaluate image quality in CMR with respect to the sequences employed, the influence of atrial fibrillation, myocardial perfusion and the impact of patient information. Further, to study patient experience in relation to MRI with the goal of improving the care of these patients.

Method: Four study designs have been used. In paper I, experimental cross-over, paper (II) experimental controlled clinical trial, paper (III) psychometric crosssectional study and paper (IV) prospective intervention study. A total of 475 patients ≥ 18 years with primarily cardiac problems (I-IV) except for those referred for MRI of the spine (III) were included in the four studies.

Result: In patients (n=20) with atrial fibrillation, a single shot steady state free precession (SS-SSFP) sequence showed significantly better image quality than the standard segmented inversion recovery fast gradient echo (IR-FGRE) sequence (I). In first-pass perfusion imaging the gradient echo-echo planar imaging sequence (GREEPI) (n=30) had lower signal-to-noise and contrast–to-noise ratios than the steady state free precession sequence (SSFP) (n=30) but displayed a higher correlation with the MPS results, evaluated both qualitatively and quantitatively (II). The MRIAnxiety Questionnaire (MRI-AQ) was validated on patients, referred for MRI of either the spine (n=193) or the heart (n=54). The final instrument had 15 items divided in two factors regarding Anxiety and Relaxation. The instrument was found to have satisfactory psychometric properties (III). Patients who prior CMR viewed an information video scored significantly (lower) better in the factor Relaxation, than those who received standard information. Patients who underwent MPS scored lower on both factors, Anxiety and Relaxation. The extra video information had no effect on CMR image quality (IV).

Conclusion: Single shot imaging in atrial fibrillation produced images with less artefact than a segmented sequence. In first-pass perfusion imaging, the sequence GRE-EPI was superior to SSFP. A questionnaire depicting anxiety during MRI showed that video information prior to imaging helped patients relax but did not result in an improvement in image quality.

Ort, förlag, år, upplaga, sidor
Linköping: Linköping University Electronic Press, 2016. , s. 74
Serie
Linköping University Medical Dissertations, ISSN 0345-0082 ; 1524
Nationell ämneskategori
Radiologi och bildbehandling Medicinsk bildbehandling Kardiologi Medicinsk laboratorie- och mätteknik Allmänmedicin
Forskningsämne
Medicin
Identifikatorer
URN: urn:nbn:se:oru:diva-77209ISBN: 978-91-7685-742-7 (tryckt)OAI: oai:DiVA.org:oru-77209DiVA, id: diva2:1360330
Disputation
2016-09-30, Originalet, Qulturum, Hus B4, 09:00 (Svenska)
Opponent
Handledare
Forskningsfinansiär
Futurum - Akademin för hälsa och vård, Jönköpings län Tillgänglig från: 2019-10-15 Skapad: 2019-10-11 Senast uppdaterad: 2019-10-21Bibliografiskt granskad

Open Access i DiVA

Magnetic Resonance Imaging of the Heart: Image quality, measurement accuracy and patient experience(1483 kB)114 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 1483 kBChecksumma SHA-512
a13cbaf62bd9498696687c6588eb8b72cbb80694093f800a214fa991261e9144373e357442242c286d411b9cfcc5af8c5dc97dd0973189b32f1df78609158e7f
Typ fulltextMimetyp application/pdf
omslag(361 kB)2 nedladdningar
Filinformation
Filnamn COVER01.pdfFilstorlek 361 kBChecksumma SHA-512
dffe0af4f54f3f86f1c4111d7fb23c8af4df6a82a05a2e9232b88a09a903cb66edc42c48bf630a90030b6c6e13fce497c08a45f03941e219fa731194dc3e912c
Typ coverMimetyp application/pdf

Övriga länkar

Fulltextpreview image

Personposter BETA

Ahlander, Britt-Marie

Sök vidare i DiVA

Av författaren/redaktören
Ahlander, Britt-Marie
Radiologi och bildbehandlingMedicinsk bildbehandlingKardiologiMedicinsk laboratorie- och mätteknikAllmänmedicin

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 114 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

isbn
urn-nbn

Altmetricpoäng

isbn
urn-nbn
Totalt: 53 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf