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Pain scales in clinical trials in newborn infants: a mapping of the evidence
Örebro universitet, Institutionen för hälsovetenskaper. (PEARL - Pain in Early Life)ORCID-id: 0000-0002-5996-2584
Lund University, Lund, Sweden.
Lund University, Lund, Sweden.
Lund University, Lund, Sweden.
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2019 (Engelska)Konferensbidrag, Poster (med eller utan abstract) (Refereegranskat)
Abstract [en]

BackgroundNumerous clinical studies have aimed at reducing pain in newborn infants. Little is known about whether the outcome measures are valid for the specific type of pain or group of infants included. 

Aim: To evaluate the reporting of pain assessments used in published trials.

MethodsA systematic search up to January 2019 was performed in Embase, PubMed, PsycInfo, Cinahl, Cochrane Library, Scopus and Luxid. Randomized and quasi-randomized clinical trials were included. Title and abstract screening followed by full text screening were performed by two independent researchers. Data extraction and quality assessment were also performed by two researchers independently.

Results: The search retrieved 3715 articles. 342 studies with a total of 16210 infants were included. 90% of the studies concerned procedural pain where the most frequently used pain scales were PIPP or PIPP-R followed by NIPS For ongoing or post-operative pain COMFORT and NFCS were mostly used. We observed a wide variation of pain scales and found numerous studies where pain scales were used that were not validated for the studied population or type of pain. 

ConclusionThis is the first scoping review reporting systematically how neonatal pain scales are used in clinical trials. There are a few validated pain assessment scales used in most clinical studies. It is crucial to choose an appropriate scale, validated for the type of pain and population of infants included in the study. The inappropriate use of pain scales raises serious concerns on ethical conduct of research and waste of resources.

Ort, förlag, år, upplaga, sidor
2019.
Nyckelord [en]
Pain, newborn infants
Nationell ämneskategori
Omvårdnad Pediatrik
Forskningsämne
Omvårdnadsforskning med medicinsk inriktning
Identifikatorer
URN: urn:nbn:se:oru:diva-77275OAI: oai:DiVA.org:oru-77275DiVA, id: diva2:1360736
Konferens
Svenskt smärtforum, Malmö, Sweden, October 17-18, 2019
Projekt
SANNI - Safe Analgesia for Neonatal Intensive CareTillgänglig från: 2019-10-14 Skapad: 2019-10-14 Senast uppdaterad: 2020-02-17Bibliografiskt granskad

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Eriksson, MatsOlsson, Emma

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Eriksson, MatsOlsson, Emma
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Institutionen för hälsovetenskaper
OmvårdnadPediatrik

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Totalt: 74 träffar
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