oru.sePublications
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Clinical features of paediatric acute-onset neuropsychiatric syndrome: findings from a case-control study
Department of Clinical Neuroscience, Center for Psychiatry Research,Karolinska Institutet; Stockholm Health Care Services, Stockholm County Council, Sweden.
Örebro University, School of Medical Sciences.ORCID iD: 0000-0002-3587-6075
2019 (English)In: BJPsych Open, E-ISSN 2056-4724, Vol. 5, no 2, article id e25Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Paediatric acute-onset neuropsychiatric syndrome (PANS), an umbrella term that includes PANDAS (paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) is suggested to be a psychiatric disorder of autoimmune aetiology. PANS is characterised by an acute onset of obsessive-compulsive disorder or restricted eating with multiple comorbid symptoms. The specificity of the PANS criteria is not fully understood.AimsTo describe a cohort of patients with PANS and to determine if PANS features relating to symptoms, onset and course are more common in PANS than in other psychiatric conditions.

METHOD: A case-control study comparing patients with interview-confirmed PANS with patients with suspected PANS and patients with a psychiatric condition but with no suspicion of PANS. Validated and non-validated measures of symptoms, onset and episodic course were used.

RESULTS: Illness in patients with interview-confirmed PANS featured an episodic course and multiple symptoms present at onset compared with the psychiatric controls. However, individuals with interview-confirmed PANS did not present a specific symptom profile.

CONCLUSIONS: PANS may be a distinct clinical entity featuring an acute onset, an episodic course and multiple symptoms at onset.Declaration of interestNone.

Place, publisher, year, edition, pages
Royal College of Psychiatrists , 2019. Vol. 5, no 2, article id e25
Keywords [en]
Pediatric acute-onset neuropsychiatric syndrome, diagnostic criteria, obsessive-compulsive disorder, pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections
National Category
Medical and Health Sciences Psychiatry
Identifiers
URN: urn:nbn:se:oru:diva-79290DOI: 10.1192/bjo.2019.10ISI: 000514362500007PubMedID: 31068234OAI: oai:DiVA.org:oru-79290DiVA, id: diva2:1387476
Available from: 2020-01-21 Created: 2020-01-21 Last updated: 2020-03-17Bibliographically approved

Open Access in DiVA

Clinical features of paediatric acute-onset neuropsychiatric syndrome: findings from a case–control study(452 kB)44 downloads
File information
File name FULLTEXT01.pdfFile size 452 kBChecksum SHA-512
73f25694f196dcfda878625c4c5681c97e323332beb28cc8decbe8b23e14313b21da2b60f6eb89a1e04b01200032b982aa7056f883bf3ffb8981e06ab64434e0
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Bejerot, Susanne

Search in DiVA

By author/editor
Bejerot, Susanne
By organisation
School of Medical Sciences
In the same journal
BJPsych Open
Medical and Health SciencesPsychiatry

Search outside of DiVA

GoogleGoogle Scholar
Total: 44 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 51 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf