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Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000
Örebro University, School of Medical Sciences. World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, Department of Laboratory Medicine, Microbiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.ORCID iD: 0000-0002-0688-2521
Örebro University, School of Medical Sciences. Örebro University Hospital. World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, Department of Laboratory Medicine, Microbiology.
Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Örebro University, School of Medical Sciences. Örebro University Hospital. World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, Department of Laboratory Medicine, Microbiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden; Institute for Global Health, University College London, London, United Kingdom.ORCID iD: 0000-0003-1710-2081
2023 (English)In: Microbiology Resource Announcements, E-ISSN 2576-098X, Vol. 12, no 3, article id e0113022Article in journal (Refereed) Published
Abstract [en]

Zoliflodacin is a promising novel antimicrobial in clinical development for treatment of gonorrhea; currently, it is in a global phase 3 randomized controlled clinical trial. High activity against global Neisseria gonorrhoeae strains has been shown. We present the complete reference genome of the zoliflodacin-resistant strain H035, which was identified in Japan in 2000.

Place, publisher, year, edition, pages
American Society for Microbiology, 2023. Vol. 12, no 3, article id e0113022
National Category
Infectious Medicine
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URN: urn:nbn:se:oru:diva-104581DOI: 10.1128/mra.01130-22ISI: 000940691300001PubMedID: 36853044Scopus ID: 2-s2.0-85150451848OAI: oai:DiVA.org:oru-104581DiVA, id: diva2:1740601
Note

Funding agencies:

Örebro County Council Research Committee

Foundation for Medical Research at Örebro University Hospital (Örebro, Sweden)

Available from: 2023-03-01 Created: 2023-03-01 Last updated: 2023-05-19Bibliographically approved

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Golparian, DanielJacobsson, SusanneUnemo, Magnus

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