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A Markov cost-effectiveness modeling framework for evaluating wound dressings: A concept for practical implementation of economic evaluations in an informed dressing selection process
Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel.
Örebro University, School of Health Sciences. Ghent University, Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent, Belgium; Örebro University, Swedish Centre for Skin and Wound Research (SCENTR), School of Health Sciences, Örebro, Sweden.ORCID iD: 0000-0003-3080-8716
Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel; Ghent University, Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent, Belgium; Department of Mathematics and Statistics and the Data Science Institute, Faculty of Sciences, Hasselt University, Hasselt, Belgium.
2024 (English)In: Journal of tissue viability, ISSN 0965-206X, Vol. 33, no 4, p. 938-948Article in journal (Refereed) Published
Abstract [en]

AIMS: Exemplify the potential of using health economy modeling and simulations to support and optimize wound dressing purchasing decisions.

MATERIALS AND METHODS: We developed a Markov cost-effectiveness modeling framework fusing clinical and industry sources of healing and cost outcomes for evaluating dressings, focusing on polymeric membrane dressings compared to passive foam dressings without active inflammation modulation components. We calculated the wound care costs for patients with and without diabetes, as well as for infected and non-infected wounds, to illustrate the effectiveness of this model in supporting decision-making.

RESULTS: The model results demonstrated that polymeric membrane dressings reduce the cumulative treatment costs compared to passive foam dressings, due to fewer dressing changes and lower associated labor costs, regardless of the initial product price differences.

CONCLUSION: Cost-effectiveness calculations should be performed in healthcare facilities to support purchasing decisions based on true cost analyses. Making purchasing decisions focusing on the dressing price alone may provide wrong estimates of the real cost differences.

Place, publisher, year, edition, pages
Elsevier, 2024. Vol. 33, no 4, p. 938-948
Keywords [en]
Cost analysis, Difficult-to-heal or non-healing wounds, Health economics, Monte Carlo computer simulations, Probabilistic Markov model
National Category
Health Care Service and Management, Health Policy and Services and Health Economy
Identifiers
URN: urn:nbn:se:oru:diva-116553DOI: 10.1016/j.jtv.2024.10.001ISI: 001407160300001PubMedID: 39368874Scopus ID: 2-s2.0-85205708222OAI: oai:DiVA.org:oru-116553DiVA, id: diva2:1903741
Note

Funding:

This work was partially supported by the Israeli Ministry of Science & Technology (Medical Devices Program Grant no. 3-17421, awarded to Professor Amit Gefen in 2020) and by an unrestricted educational grant from Ferris Mfg. Corp. (Fort Worth, TX, USA)

Available from: 2024-10-07 Created: 2024-10-07 Last updated: 2025-02-05Bibliographically approved

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Beeckman, Dimitri

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