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Lung function and respiratory symptoms in hard metal workers exposed to cobalt
Department of Occupational and Environmental Medicine, Uppsala University Hospital, Uppsala, Sweden.
Department of Clinical Physiology, Södersjukhuset, Stockholm, Sweden; Division of Occupational and Environmental Medicine, Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden.
Department of Occupational and Environmental Medicine, Örebro University Hospital, Örebro, Sweden.
Department of Occupational and Environmental Medicine Uppsala University Hospital, Uppsala, Sweden.
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2012 (Engelska)Ingår i: Journal of Occupational and Environmental Medicine, ISSN 1076-2752, E-ISSN 1536-5948, Vol. 54, nr 4, s. 409-13Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Objective: To follow-up lung function and airway symptoms in workers exposed to cobalt dust at a hard metal plant.

Methods: A total of 582 employees underwent spirometry and completed a questionnaire. A historical exposure matrix was created, assigning figures for historical and recent work-related exposure.

Results: At the time of employment, 5% reported symptoms from respiratory tract. At follow-up, 5% suffered from persistent coughing and 7% reported asthma; 20% were daily smokers. Among nonsmokers without asthma, an evident, statistically nonsignificant, dose-response effect was seen between increasing cobalt exposure and decline in FEV1 (forced expiratory volume in the first second). In all exposure categories, the FEV1 in smokers declined 10 mL more per year than for nonsmokers.

Conclusions: Even low levels of cobalt exposure seem to hamper lung function both in smokers and nonsmokers. This impact is considered low in relation to the effect of aging.

Ort, förlag, år, upplaga, sidor
Philadelphia, USA: Lippincott Williams & Wilkins, 2012. Vol. 54, nr 4, s. 409-13
Nationell ämneskategori
Medicin och hälsovetenskap
Identifikatorer
URN: urn:nbn:se:oru:diva-44198DOI: 10.1097/JOM.0b013e31824d2d7eISI: 000302589300004PubMedID: 22446572Scopus ID: 2-s2.0-84859640748OAI: oai:DiVA.org:oru-44198DiVA, id: diva2:801642
Tillgänglig från: 2015-04-09 Skapad: 2015-04-09 Senast uppdaterad: 2018-08-28Bibliografiskt granskad

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Gunnarsson, Lars-Gunnar

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