Analysis of brominated flame retardants and their derivatives by atmospheric pressure chemical ionization using gas chromatography coupled to tandem quadrupole mass spectrometry
2017 (English)In: Talanta: The International Journal of Pure and Applied Analytical Chemistry, ISSN 0039-9140, E-ISSN 1873-3573, Vol. 162, 618-624 p.Article in journal (Refereed) Published
A validated method using an atmospheric pressure chemical ionization source for coupling gas chromatography (GC-APCI) to tandem quadrupole mass spectrometry (MS/MS) for the determination of brominated flame retardants (BFRs) is presented. Polybrominated diphenyl ethers (PBDEs), their methoxylated derivatives (MeO-PBDEs) and other emerging BFRs were included in this study. The method showed good linearity and repeatability. The relative standard deviation (RSD) of the relative response factors (RRFs) of all compounds was less than 16%. Repeatability for BFRs was tested on one or two concentration levels of calibration standardswith RSDs for RRFs below 16%. The lowest calibration standards (0.075 –0.1 pg/μL for emerging BFRs, BDE 209 and MeO-PBDEs mixtures, 0.625 –6.25 pg/μL for Br1-9 PBDEs mixtures) were used as instrument detection limits (IDL). The method was applied on biotic samples, including fish, osprey, and seal. In general, BDE209 and decabromodiphenyl ethane (DBDPE) were detected in 50% of the seal samples. A 100% detection rate was achieved for 6-MeO-BDE47 in all the samples (72 –580 pg/g ww in osprey samples, 24 000 –96 000 pg/g ww in seal samples and 78–99 pg/g ww in fish samples). AllBr3-6PBDEs (BDE28, 47, 99, 100, 153, 154) were detected in all the samples (ranging from 12 to 20 000 pg/g ww), while BDE183 was detected in 60% of the osprey eggs, 20% of the seal samples and below MDL in all fish samples. The results presented indicate the capability of the GC-APCI-MS/MS system for the detection and quantification of BFRs.
Place, publisher, year, edition, pages
Amsterdam, Netherlands: Elsevier, 2017. Vol. 162, 618-624 p.
BFR, PBDE, MeO-PBDE, gas chromatography-atmospheric pressure chemical ionization (GC-APCI), tandem quadrupole mass spectrometry (MS/MS)
Research subject Chemistry
IdentifiersURN: urn:nbn:se:oru:diva-53049DOI: 10.1016/j.talanta.2016.10.060ISI: 000389088700083PubMedID: 27837880ScopusID: 2-s2.0-84994381585OAI: oai:DiVA.org:oru-53049DiVA: diva2:1038809
China Scholarship Council 201206400003
Czech Ministry of Education, Youth and Sports LO1214 LM2015051
Ingrid Ericson Jogsten 201400572016-10-192016-10-192017-01-11Bibliographically approved