International renal-cell cancer study. IV. Occupation
1995 (English)In: International Journal of Cancer, ISSN 0020-7136, E-ISSN 1097-0215, Vol. 61, no 5, 601-605 p.Article in journal (Refereed) Published
The relationship between renal-cell cancer (RCC) and occupation was investigated in an international multicenter population-based case-control study. Study centers in Australia, Denmark, Germany, Sweden and the United States interviewed 1732 incident RCC cases and 2309 controls. Significant associations were found with employment in the blast-furnace or the coke-oven industry [relative risk (RR), 1.7; 95% confidence interval (CI), 1.1-2.7], the iron and steel industry (RR, 1.6; 95% CI, 1.2-2.2) and exposure to asbestos (RR, 1.4; 95% CI, 1.1-1.8), cadmium (RR, 2.0; 95% CI, 1.0-3.9), dry-cleaning solvents (RR, 1.4; 95% CI, 1.1-1.7), gasoline (RR, 1.6; 95% CI, 1.2-2.0) and other petroleum products (RR, 1.6; 95% CI, 1.3-2.1). Asbestos, petroleum products and dry-cleaning solvents appear to merit further investigation, in view of the relationship between risk and duration of employment or exposure and after adjustment for confounding. There was a negative association between RCC and education, but it was not consistent across all centers. Overall, the results of our multicenter case-control study suggest that occupation may be more important in the etiology of RCC than indicated by earlier studies.
Place, publisher, year, edition, pages
New York, USA: John Wiley & Sons, 1995. Vol. 61, no 5, 601-605 p.
Aged, Carcinoma, Renal Cell/*epidemiology, Case-Control Studies, Educational Status, Female, Humans, Kidney Neoplasms/*epidemiology, Male, Middle Aged, *Occupations, Odds Ratio, Risk, Smoking
Cancer and Oncology
IdentifiersURN: urn:nbn:se:oru:diva-48992DOI: 10.1002/ijc.2910610503ISI: A1995RB28300002PubMedID: 7768630ScopusID: 2-s2.0-0028799593ISBN: 0020-7136 (Print) 0020-7136 (Linking)OAI: oai:DiVA.org:oru-48992DiVA: diva2:1061274