oru.sePublikationer
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
International renal-cell-cancer study. VI. the role of medical and family history
Division of Epidemiology, German Cancer Research Centre, Heidelberg, Germany; .
Humboldt Hospital, Berlin, Germany.
Danish Cancer Registly, Danish Cancer Society, Copenhagen, Denmark.
Western Clinical School, University of Sydney, sydney, Australia.
Show others and affiliations
1996 (English)In: International Journal of Cancer, ISSN 0020-7136, E-ISSN 1097-0215, Vol. 66, no 6, 723-726 p.Article in journal (Refereed) Published
Abstract [en]

A number of medical conditions have been linked with renal-cell cancer, although the evidence is not consistent in every case. In a large international case-control study of renal-cell cancer, we examined, among other hypotheses, associations with a personal history of certain medical conditions and a family history of cancer of the kidney or thyroid. Relative risks (RR), adjusted for the effects of age, gender, body-mass index, tobacco smoking and study centre, were significantly increased by a history of kidney stones or thyroid or kidney disease. The RR were not altered by additional adjustment for hypertension, or when diagnoses were restricted to those made at least 5 or 10 years before 1987 (the usual "cut-off" date). The link with kidney injury is particularly likely to be affected by recall bias. Increased RR of borderline significance were found for kidney infection (RR, 1.2) and diabetes (RR, 1.4). Having one first-degree relative with kidney cancer was associated with a significantly increased risk of renal-cell cancer (RR, 1.6; 95% Cl, 1.1-2.4). Seven cases reported 2 first-degree relatives with kidney cancer. No controls had first-degree relatives with kidney cancer. None of our participants reported having von Hippel-Lindau disease. The data suggests that a few conditions of the kidney are strongly associated with renal-cell cancer and that heredity plays a role in a small proportion of cases.

Place, publisher, year, edition, pages
New York, USA: John Wiley & Sons, 1996. Vol. 66, no 6, 723-726 p.
Keyword [en]
Adult, Aged, Bias (Epidemiology), Carcinoma, Renal Cell/*epidemiology/genetics, Case-Control Studies, Comorbidity, Denmark/epidemiology, Diabetes Mellitus/epidemiology, Female, Germany/epidemiology, Humans, Hypertension/epidemiology, Kidney Diseases/epidemiology, Kidney Neoplasms/*epidemiology/genetics, Male, Medical Records, Middle Aged, Minnesota/epidemiology, Neoplastic Syndromes, Hereditary/epidemiology, New South Wales/epidemiology, Risk, Smoking/epidemiology, Sweden/epidemiology, Thyroid Diseases/epidemiology
National Category
Cancer and Oncology
Identifiers
URN: urn:nbn:se:oru:diva-49001DOI: 10.1002/(SICI)1097-0215(19960611)66:6<723::AID-IJC2>3.0.CO;2-1ISI: A1996UP06300002PubMedID: 8647639Scopus ID: 2-s2.0-15844431133ISBN: 0020-7136 (Print) 0020-7136 (Linking) (print)OAI: oai:DiVA.org:oru-49001DiVA: diva2:1061284
Available from: 2017-01-01 Created: 2016-03-06 Last updated: 2017-10-18Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedScopus

Search in DiVA

By author/editor
Lindblad, Per
In the same journal
International Journal of Cancer
Cancer and Oncology

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 19 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf