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Risk for self-reported anorexia or bulimia nervosa based on drive for thinness and negative affect clusters/dimensions during adolescence: A three-year prospective study of the TChAD cohort
University of Extremadura Medical School, Badajoz, Spain.
Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina, USA.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID iD: 0000-0002-6851-3297
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2015 (English)In: International Journal of Eating Disorders, ISSN 0276-3478, E-ISSN 1098-108X, Vol. 48, no 6, 692-699 p.Article in journal (Refereed) Published
Abstract [en]

Objective: This study explored the cross-sectional and predictive effect of drive for thinness and/or negative affect scores on the development of self-reported anorexia nervosa (AN) and bulimia nervosa (BN).

Method: K-means were used to cluster the Eating Disorder Inventory-Drive for Thinness (DT) and Child Behavior Checklist Anxious/Depressed (A/D) scores from 615 unrelated female twins at age 16-17. Logistic regressions were used to assess the effect of these clusters on self-reported eating disorder diagnosis at ages 16-17 (n = 565) and 19-20 (n = 451).

Results: DT and A/D scores were grouped into four clusters: Mild (scores lower than 90th percentile on both scales), DT (higher scores only on DT), A/D (higher scores only on A/D), and DT-A/D (higher scores on both the DT and A/D scales). DT and DT-A/D clusters at age 16-17 were associated cross-sectionally with AN and both cross-sectionally and longitudinally with BN. The DT-A/D cluster had the highest prevalence of AN at follow-up compared with all other clusters. Similarly, an interaction was observed between DT and A/D that predicted risk for AN.

Discussion: Having elevated DT and A/D scores may increase risk for eating disorder symptomatology above and beyond a high score on either alone. Findings suggest that cluster modeling based on DT and A/D may be useful to inform novel and useful intervention strategies for AN and BN in adolescents.

Place, publisher, year, edition, pages
Hoboken, USA: Wiley-Blackwell, 2015. Vol. 48, no 6, 692-699 p.
Keyword [en]
Drive for thinness, anxiety, depression, negative affect, subtyping, eating disorders, anorexia, bulimia, risk
National Category
Medical and Health Sciences Psychiatry Psychology Nutrition and Dietetics
Identifiers
URN: urn:nbn:se:oru:diva-54501DOI: 10.1002/eat.22431ISI: 000360075900018PubMedID: 26013185Scopus ID: 2-s2.0-84939507345OAI: oai:DiVA.org:oru-54501DiVA: diva2:1064278
Funder
NIH (National Institute of Health)Swedish Research Council
Note

Funding Agencies:

Swedish Council for Working Life and Social Research

Available from: 2017-01-12 Created: 2017-01-12 Last updated: 2017-01-19Bibliographically approved

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