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Coexisting psychiatric problems and stressful life events in adults with symptoms of ADHD: a large Swedish population-based study of twins
Department of Women's and Children's Health, Child and Adolescent Psychiatric Unit, Astrid Lindgren Children's Hospital, Karolinska Institutet, Stockholm, Sweden.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID iD: 0000-0002-6851-3297
Department of Women's and Children's Health, Child and Adolescent Psychiatric Unit, Astrid Lindgren Children's Hospital, Karolinska Institutet, Stockholm, Sweden.
2012 (English)In: Journal of Attention Disorders, ISSN 1087-0547, E-ISSN 1557-1246, Vol. 16, no 1, 13-22 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To explore the associations of subtypes of adult ADHD with other psychiatric problems, stressful life events, and sex differences.

METHOD: Odds ratios were calculated using information from 17,899 participants from a population-based survey of adult twins born in Sweden between 1959 and 1985.

RESULTS: Symptoms of attention deficit hyperactivity disorder (ADHD) were associated with an increased risk for symptoms of (odds ratio [95% confidence interval]): generalized anxiety disorder (5.6 [4.3; 6.5]), major depression (2.8 [2.4; 3.2]), bipolar disorder (8.0 [5.1; 12.6]), obsessive-compulsive disorder (3.9 [3.1; 4.9]), and alcohol dependence (2.6 [2.2; 3.1]). Symptoms of ADHD were found to be associated with an increased risk for stressful life events (1.8 [1.3; 2.4]). No significant difference in comorbidity was observed between the two sexes.

CONCLUSION: Both women and men with ADHD are at increased risk for symptoms of other psychiatric disorders. They are also at increased risk for stressful life events.

Place, publisher, year, edition, pages
Sage Publications, 2012. Vol. 16, no 1, 13-22 p.
Keyword [en]
ADHD; comorbidities; adults; population-based study; twin study; generalized linear mixed effects models
National Category
Psychology Psychiatry
Research subject
Psychology; Psychiatry
Identifiers
URN: urn:nbn:se:oru:diva-54548DOI: 10.1177/1087054710376909ISI: 000298352300002PubMedID: 20686099Scopus ID: 2-s2.0-84055214125OAI: oai:DiVA.org:oru-54548DiVA: diva2:1064353
Funder
Swedish Research CouncilThe Swedish Brain Foundation
Note

Funding Agencies:

Kempe-Carlgrenska Foundation

Clas Groschinsky Memorial Foundation

Karolinska Institutet Center of Neurodevelopmental Disorders

Available from: 2017-01-12 Created: 2017-01-12 Last updated: 2017-01-25Bibliographically approved

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