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Analytical Specificity and Sensitivity of the APTIMA Combo 2 and APTIMA GC Assays for Detection of Commensal Neisseria Species and Neisseria gonorrhoeae on the Gen-Probe Panther Instrument
Natl Reference Lab Pathogen Neisseria, WHO Collaborating Ctr Gonorrhoea & Other STIs, Orebro, Sweden..
Royal Womens Hosp, Dept Microbiol & Infect Dis, Parkville, Vic, Australia..
Orebro University Hospital. Natl Reference Lab Pathogen Neisseria, WHO Collaborating Ctr Gonorrhoea & Other STIs, Orebro, Sweden.;Orebro Univ Hosp, Dept Lab Med, WHO Collaborating Ctr Gonorrhoea & Other STIs, SE-70185 Orebro, Sweden..
2013 (English)In: Sexually Transmitted Diseases, ISSN 0148-5717, E-ISSN 1537-4521, Vol. 40, no 2, 175-178 p.Article in journal (Refereed) Published
Abstract [en]

Genetic detection of Neisseria gonorrhoeae is replacing culture for increased diagnostic sensitivity. Specificity of several nucleic acid amplification tests is suboptimal. Herein, the Gen-Probe APTIMA Combo 2 and APTIMA GC assays had 100% specificity and 100% sensitivity after confirmatory testing, when testing 298 isolates of non-gonococcal Neisseria and related species and 205 gonococcal isolates.

Place, publisher, year, edition, pages
2013. Vol. 40, no 2, 175-178 p.
National Category
Infectious Medicine
Identifiers
URN: urn:nbn:se:oru:diva-56546DOI: 10.1097/OLQ.0b013e3182787e45ISI: 000313618100017PubMedID: 23324980OAI: oai:DiVA.org:oru-56546DiVA: diva2:1082706
Available from: 2017-03-17 Created: 2017-03-17 Last updated: 2017-03-17Bibliographically approved

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