oru.sePublikationer
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Increased risk of preterm birth in women with autoimmune hepatitis: a nationwide cohort study
Visby Hosp, Dept Med, SE-62184 Visby, Sweden.;Karolinska Inst, Dept Med, Gastroenterol & Hepatol Unit, Stockholm, Sweden..
Örebro University Hospital. Örebro Univ Hosp, Dept Pediat, Örebro, Sweden.;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden..
Karolinska Inst, Dept Med, Gastroenterol & Hepatol Unit, Stockholm, Sweden.;Karolinska Hosp, Div Hepatol, S-10401 Stockholm, Sweden..
Karolinska Hosp & Inst, Dept Med, Clin Epidemiol Unit, Stockholm, Sweden..
Show others and affiliations
2016 (English)In: Liver international (Print), ISSN 1478-3223, E-ISSN 1478-3231, Vol. 36, no 1, 76-83 p.Article in journal (Refereed) Published
Abstract [en]

Background & Aims: The aim of our study was to investigate the risks of pregnancy and childbirth complications in women with autoimmune hepatitis compared to the population controls. Methods: In a nationwide cohort study of all pregnancies between 2006 and 2011 we investigated the risks of adverse pregnancy outcome in 171 births in women with diagnosed autoimmune hepatitis using the data from the Swedish Medical Birth and Patient Registries. Births to women without autoimmune hepatitis served as population controls (n = 576 642). Relative risks (RR) with 95% confidence intervals (CI) were calculated using Poisson regression models adjusting for potential confounders. Results: Women with AIH had an increased risk of gestational diabetes (RR = 4.35, 95% CI 2.21-8.57), of preterm birth (RR = 3.21, 95% CI 1.97-4.92) and of low-birth-weight child (RR = 2.51, 95% CI 1.51-4.19). We found no statistically significant association between autoimmune hepatitis and pre-eclampsia, caesarean section, low 5-min Apgar score, small for gestational age birth, congenital malformation and neonatal mortality. Conclusions: Autoimmune hepatitis is a risk factor for adverse pregnancy outcomes. High quality prenatal and antenatal care is important for women with autoimmune hepatitis and their infants.

Place, publisher, year, edition, pages
2016. Vol. 36, no 1, 76-83 p.
Keyword [en]
gestational diabetes, pre-eclampsia, stillbirth
National Category
Gastroenterology and Hepatology
Identifiers
URN: urn:nbn:se:oru:diva-56596DOI: 10.1111/liv.12901ISI: 000367723500009PubMedID: 26098001OAI: oai:DiVA.org:oru-56596DiVA: diva2:1083206
Available from: 2017-03-20 Created: 2017-03-20 Last updated: 2017-11-29Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Ludvigsson, Jonas F.Hoijer, Jonas
By organisation
Örebro University Hospital
In the same journal
Liver international (Print)
Gastroenterology and Hepatology

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 96 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf