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The Oslo definitions for coeliac disease and related terms
Orebro University Hospital. Karolinska Inst, Clin Epidemiol Unit, Dept Med, Stockholm, Sweden.;Orebro Univ Hosp, Dept Paediat, Orebro, Sweden..ORCID iD: 0000-0003-1024-5602
Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Gastroenterol, Boston, MA 02215 USA..
Del Salvador Univ, Dept Med, Dr C Bonorino Udaondo Gastroenterol Hosp, Buenos Aires, DF, Argentina..
Univ Pavia, Dept Internal Med 1, Coeliac Ctr, I-27100 Pavia, Italy..
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2013 (English)In: Gut, ISSN 0017-5749, E-ISSN 1468-3288, Vol. 62, no 1, 43-52 p.Article in journal (Refereed) Published
Abstract [en]

Objective The literature suggests a lack of consensus on the use of terms related to coeliac disease (CD) and gluten. Design A multidisciplinary task force of 16 physicians from seven countries used the electronic database PubMed to review the literature for CD-related terms up to January 2011. Teams of physicians then suggested a definition for each term, followed by feedback of these definitions through a web survey on definitions, discussions during a meeting in Oslo and phone conferences. In addition to 'CD', the following descriptors of CD were evaluated (in alphabetical order): asymptomatic, atypical, classical, latent, non-classical, overt, paediatric classical, potential, refractory, silent, subclinical, symptomatic, typical, CD serology, CD autoimmunity, genetically at risk of CD, dermatitis herpetiformis, gluten, gluten ataxia, gluten intolerance, gluten sensitivity and gliadin-specific antibodies. Results CD was defined as 'a chronic small intestinal immune-mediated enteropathy precipitated by exposure to dietary gluten in genetically predisposed individuals'. Classical CD was defined as 'CD presenting with signs and symptoms of malabsorption. Diarrhoea, steatorrhoea, weight loss or growth failure is required.' 'Gluten-related disorders' is the suggested umbrella term for all diseases triggered by gluten and the term gluten intolerance should not to be used. Other definitions are presented in the paper. Conclusion This paper presents the Oslo definitions for CD-related terms.

Place, publisher, year, edition, pages
2013. Vol. 62, no 1, 43-52 p.
National Category
Gastroenterology and Hepatology
Identifiers
URN: urn:nbn:se:oru:diva-56619DOI: 10.1136/gutjnl-2011-301346ISI: 000312214000008PubMedID: 22345659OAI: oai:DiVA.org:oru-56619DiVA: diva2:1083341
Available from: 2017-03-21 Created: 2017-03-21 Last updated: 2017-03-21Bibliographically approved

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