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Reversibility of antibiotic resistance
Orebro University Hospital. Department of Laboratory Medicine, Clinical Microbiology.
2014 (English)In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 119, no 2, 142-148 p.Article, review/survey (Refereed) Published
Abstract [en]

Although theoretically attractive, the reversibility of resistance has proven difficult in practice, even though antibiotic resistance mechanisms induce a fitness cost to the bacterium. Associated resistance to other antibiotics and compensatory mutations seem to ameliorate the effect of antibiotic interventions in the community. In this paper the current understanding of the concepts of reversibility of antibiotic resistance and the interventions performed in hospitals and in the community are reviewed.

Place, publisher, year, edition, pages
Informa Healthcare, 2014. Vol. 119, no 2, 142-148 p.
Keyword [en]
Antibiotic resistance, fitness, intervention
National Category
Family Medicine
Identifiers
URN: urn:nbn:se:oru:diva-56728DOI: 10.3109/03009734.2014.903323ISI: 000336526100012PubMedID: 24836051ScopusID: 2-s2.0-84900861351OAI: oai:DiVA.org:oru-56728DiVA: diva2:1083932
Available from: 2017-03-23 Created: 2017-03-23 Last updated: 2017-03-23Bibliographically approved

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CiteExportLink to record
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Citation style
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