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Analytical Evaluation of GeneXpert CT/NG, the First Genetic Point-of-Care Assay for Simultaneous Detection of Neisseria gonorrhoeae and Chlamydia trachomatis
Royal Womens Hosp, Dept Microbiol & Infect Dis, Parkville, Vic, Australia.;Univ Melbourne, Royal Womens Hosp, Dept Obstet & Gynaecol, Parkville, Vic 3052, Australia.;Murdoch Childrens Res Inst, Parkville, Vic, Australia..
Orebro University Hospital. Dept Lab Med, WHO Collaborating Ctr Gonorrhoea & Other STIs, Orebro, Sweden..
Orebro Univ Hosp, Dept Lab Med, WHO Collaborating Ctr Gonorrhoea & Other STIs, Orebro, Sweden..
Univ Melbourne, Royal Womens Hosp, Dept Obstet & Gynaecol, Parkville, Vic 3052, Australia.;Murdoch Childrens Res Inst, Parkville, Vic, Australia..
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2013 (English)In: Journal of Clinical Microbiology, ISSN 0095-1137, E-ISSN 1098-660X, Vol. 51, no 6, 1945-1947 p.Article in journal (Refereed) Published
Abstract [en]

GeneXpert CT/NG was evaluated with 372 characterized bacterial strains. Sensitivity of 10 genome copies/reaction was obtained for both agents. Four Neisseria mucosa and two Neisseria subflava isolates were positive for one of two gonococcal targets; however, the assay flagged all as negative. The assay was analytically highly sensitive and specific.

Place, publisher, year, edition, pages
2013. Vol. 51, no 6, 1945-1947 p.
National Category
Microbiology in the medical area
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URN: urn:nbn:se:oru:diva-56768DOI: 10.1128/JCM.00806-13ISI: 000319197800049PubMedID: 23554203OAI: oai:DiVA.org:oru-56768DiVA: diva2:1084050
Available from: 2017-03-23 Created: 2017-03-23 Last updated: 2017-03-23Bibliographically approved

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