oru.sePublikationer
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Carbohydrates and insulin resistance in clinical nutrition: Recommendations from the ESPEN expert group
Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Center for Translational Research in Aging & Longevity, Department of Health and Kinesiology, Texas A & M University, College Station, TX, USA.
Department of Medical, Surgical and Health Sciences, Internal Medicine, University of Trieste, Trieste, Italy.
Department of Nutritional Medicine/Prevention, University of Hohenheim, Stuttgart, Germany.
Show others and affiliations
2017 (English)In: Clinical Nutrition, ISSN 0261-5614, E-ISSN 1532-1983, Vol. 36, no 2, 355-363 p.Article, review/survey (Refereed) Published
Abstract [en]

Growing evidence underscores the important role of glycemic control in health and recovery from illness. Carbohydrate ingestion in the diet or administration in nutritional support is mandatory, but carbohydrate intake can adversely affect major body organs and tissues if resulting plasma glucose becomes too high, too low, or highly variable. Plasma glucose control is especially important for patients with conditions such as diabetes or metabolic stress resulting from critical illness or surgery. These patients are particularly in need of glycemic management to help lessen glycemic variability and its negative health consequences when nutritional support is administered. Here we report on recent findings and emerging trends in the field based on an ESPEN workshop held in Venice, Italy, 8-9 November 2015. Evidence was discussed on pathophysiology, clinical impact, and nutritional recommendations for carbohydrate utilization and management in nutritional support. The main conclusions were: a) excess glucose and fructose availability may exacerbate metabolic complications in skeletal muscle, adipose tissue, and liver and can result in negative clinical impact; b) low-glycemic index and high-fiber diets, including specialty products for nutritional support, may provide metabolic and clinical benefits in individuals with obesity, insulin resistance, and diabetes; c) in acute conditions such as surgery and critical illness, insulin resistance and elevated circulating glucose levels have a negative impact on patient outcomes and should be prevented through nutritional and/or pharmacological intervention. In such acute settings, efforts should be implemented towards defining optimal plasma glucose targets, avoiding excessive plasma glucose variability, and optimizing glucose control relative to nutritional support. (C) 2016 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism.

Place, publisher, year, edition, pages
Churchill Livingstone , 2017. Vol. 36, no 2, 355-363 p.
Keyword [en]
Clinical nutrition, Carbohydrates, Insulin resistance
National Category
Nutrition and Dietetics
Identifiers
URN: urn:nbn:se:oru:diva-57777DOI: 10.1016/j.clnu.2016.09.010ISI: 000399624700003PubMedID: 27686693ScopusID: 2-s2.0-84998911197OAI: oai:DiVA.org:oru-57777DiVA: diva2:1097953
Available from: 2017-05-23 Created: 2017-05-23 Last updated: 2017-05-23Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedScopus

Search in DiVA

By author/editor
Ljungqvist, Olle
By organisation
School of Medical SciencesOrebro University Hospital
In the same journal
Clinical Nutrition
Nutrition and Dietetics

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 20 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf