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Lipidomics in biomedical research-practical considerations
Örebro University, School of Science and Technology. Department of Chemistry.
Steno Diabetes Center A/S, Gentofte, Denmark .
Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, Finland.
2017 (English)In: Biochimica et Biophysica Acta, ISSN 0006-3002, E-ISSN 1878-2434, Vol. 1862, no 8, 800-803 p.Article in journal (Refereed) Published
Abstract [en]

Lipids have many central physiological roles including as structural components of cell membranes, energy storage sources and intermediates in signaling pathways. Lipid-related disturbances are known to underlie many diseases and their co-morbidities. The emergence of lipidomics has empowered researchers to study lipid metabolism at the cellular as well as physiological levels at a greater depth than was previously possible. The key challenges ahead in the field of lipidomics in medical research lie in the development of experimental protocols and in silico techniques needed to study lipidomes at the systems level. Clinical questions where lipidomics may have an impact in healthcare settings also need to be identified, both from the health outcomes and health economics perspectives. This article is part of a Special Issue entitled: BBALIP_Lipidomics Opinion Articles edited by Sepp Kohlwein.

Place, publisher, year, edition, pages
Elsevier, 2017. Vol. 1862, no 8, 800-803 p.
Keyword [en]
Biomarkers, data processing, lipidomics, mass spectrometry, metabolomics, quality control
National Category
Cell and Molecular Biology
Research subject
Biomedicine
Identifiers
URN: urn:nbn:se:oru:diva-57324DOI: 10.1016/j.bbalip.2017.04.002ISI: 000404796900016PubMedID: 28408341Scopus ID: 2-s2.0-85018622795OAI: oai:DiVA.org:oru-57324DiVA: diva2:1103702
Available from: 2017-05-30 Created: 2017-05-30 Last updated: 2017-10-18Bibliographically approved

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Hyötyläinen, Tuulia

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