oru.sePublikationer
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Pesticide exposure in farming and forestry and the risk of uveal melanoma
Bremen Inst Prevent Res & Social Med, D-28359 Bremen, Germany.;Ruhr Univ Bochum, Inst Prevent & Occupat Med German Social Accid In, Bochum, Germany..
Univ Copenhagen, Inst Publ Hlth, Copenhagen, Denmark..ORCID iD: 0000-0003-4785-5236
UCL, Inst Ophthalmol, London, England..
Univ Zurich, NICER, Zurich, Switzerland..
Show others and affiliations
2012 (English)In: Cancer Causes and Control, ISSN 0957-5243, E-ISSN 1573-7225, Vol. 23, no 1, 141-151 p.Article in journal (Refereed) Published
Abstract [en]

Since pesticides are disputed risk factors for uveal melanoma, we studied the association between occupational pesticide exposure and uveal melanoma risk in a case-control study from nine European countries. Incident cases of uveal melanoma and population as well as hospital controls were included and frequency-matched by country, 5-year age groups and sex. Self-reported exposure was quantified with respect to duration of exposure and pesticide application method. We calculated the exposure intensity level based on application method and use of personal protective equipment. Odds ratios (OR) and 95% confidence intervals (95% CI) were estimated by unconditional logistic regression analyses and adjusted for several potential confounders. 293 case and 3,198 control subjects were interviewed. We did not identify positive associations with activities in farming or forestry, pesticide application or pesticide mixing. No consistent positive associations were seen with exposure intensity level scores either. The only statistically significantly raised association in this study was for exposure to chemical fertilizers in forestry (OR = 8.93; 95% CI 1.73-42.13), but this observation was based on only six exposed subjects. Results did not change when we restricted analyses to morphologically verified cases and excluded proxy interviews as well as cancer controls. We did not observe effect modification by sex or eye color. Risk estimates for pesticide exposures and occupational activities in agriculture and forestry were not increased and did not indicate a hormonal mechanism due to these exposures.

Place, publisher, year, edition, pages
SPRINGER , 2012. Vol. 23, no 1, 141-151 p.
Keyword [en]
Agriculture, Animal husbandry, Chemical fertilizers, Multicenter study, Ocular melanoma
National Category
Agricultural Occupational Health and Safety Cancer and Oncology
Identifiers
URN: urn:nbn:se:oru:diva-58344DOI: 10.1007/s10552-011-9863-zISI: 000297757400014PubMedID: 22052342OAI: oai:DiVA.org:oru-58344DiVA: diva2:1116909
Available from: 2017-06-28 Created: 2017-06-28 Last updated: 2017-06-28

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Lynge, ElsebethGorini, GiuseppeHardell, LennartAhrens, Wolfgang
By organisation
Örebro University Hospital
In the same journal
Cancer Causes and Control
Agricultural Occupational Health and SafetyCancer and Oncology

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 1 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf