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Clinical Neisseria gonorrhoeae isolate with a N. meningitidis porA gene and no prolyliminopeptidase activity, Sweden, 2011-danger of false-negative genetic and culture diagnostic results
Orebro Univ Hosp, WHO Collaborating Ctr Gonorrhoea & Other STIs, Swedish Reference Lab Pathogen Neisseria, Dept Lab Med, Orebro, Sweden..
Orebro Univ Hosp, WHO Collaborating Ctr Gonorrhoea & Other STIs, Swedish Reference Lab Pathogen Neisseria, Dept Lab Med, Orebro, Sweden..
Örebro University Hospital.
2012 (English)In: Eurosurveillance, ISSN 1025-496X, E-ISSN 1560-7917, Vol. 17, no 9, 5-7 p., 20102Article in journal (Refereed) Published
Abstract [en]

We describe a Neisseria gonorrhoeae strain, found in Sweden in 2011, that harbours a N. meningitidis porA gene causing false-negative results in PCRs targeting the gonococcal porA pseudogene. Furthermore, the strain had no prolyliminopeptidase (PIP) activity that many commercial biochemical kits for species verification in culture rely on. Enhanced awareness of the spread of such strains and screening for them can be crucial.

Place, publisher, year, edition, pages
EUR CENTRE DIS PREVENTION & CONTROL , 2012. Vol. 17, no 9, 5-7 p., 20102
National Category
Infectious Medicine Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
Identifiers
URN: urn:nbn:se:oru:diva-58671ISI: 000301357800002OAI: oai:DiVA.org:oru-58671DiVA: diva2:1121615
Available from: 2017-07-12 Created: 2017-07-12 Last updated: 2017-07-12

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