oru.sePublikationer
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
A Family-Based Study of the Association Between Labor Induction and Offspring Attention-Deficit Hyperactivity Disorder and Low Academic Achievement
Department of Psychological and Brain Sciences, Indiana University, Bloomington IN, USA.
Department of Psychological and Brain Sciences, Indiana University, Bloomington IN, USA.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, USA.
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine at Brigham and Women’s Hospital, Harvard Medical School, Boston, USA; Department of Anesthesia, Critical Care, and Pain Medicine at Massachusetts General Hospital, Harvard Medical School, Boston, USA.
Show others and affiliations
2017 (English)In: Behavior Genetics, ISSN 0001-8244, E-ISSN 1573-3297, Vol. 47, no 4, 383-393 p.Article in journal (Refereed) Published
Abstract [en]

The current study examined associations between labor induction and both (1) offspring attention-deficit hyperactivity disorder (ADHD) diagnosis in a Swedish birth cohort born 1992-2005 (n = 1,085,008) and (2) indices of offspring low academic achievement in a sub-cohort born 1992-1997 (n = 489,196). Associations were examined in the entire sample (i.e., related and unrelated individuals) with adjustment for measured covariates and, in order to account for unmeasured confounders shared within families, within differentially exposed cousins and siblings. We observed an association between labor induction and offspring ADHD diagnosis and low academic achievement in the population. However, these associations were fully attenuated after adjusting for measured covariates and unmeasured factors that cousins and siblings share. The results suggest that observed associations between labor induction and ADHD and low academic achievement may be due to genetic and/or shared environmental factors that influence both mothers' risk of labor induction and offspring neurodevelopment.

Place, publisher, year, edition, pages
Springer, 2017. Vol. 47, no 4, 383-393 p.
Keyword [en]
Labor induction, Attention-deficit hyperactivity disorder, Academic achievement, Family studies, Sibling comparison, Cousin comparison
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:oru:diva-58942DOI: 10.1007/s10519-017-9852-4ISI: 000403569500002PubMedID: 28551761Scopus ID: 2-s2.0-85019730858OAI: oai:DiVA.org:oru-58942DiVA: diva2:1134383
Note

Funding Agencies:

Indiana Clinical and Translational Sciences Institute: Pediatric Project Development Team  

Swedish Research Council through the Swedish Initiative for Research on Microdata in the Social and Medical Sciences (SIMSAM)  340-2013-5867 

National Institute of Health, T32 Grant  HD 07475 

Institutional Review Board at the Karolinska Institutet  

Available from: 2017-08-18 Created: 2017-08-18 Last updated: 2017-10-23Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedScopus

Search in DiVA

By author/editor
Larsson, Henrik
By organisation
School of Medical Sciences
In the same journal
Behavior Genetics
Psychiatry

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 25 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf