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Validation of a home environment test battery for supporting assessments in advanced Parkinson’s disease
Academy of Industry and Society, Computer Science, Dalarna University, Borlänge, Sweden; Department of Medical Sciences, Biomedical Informatics and Engineering, Uppsala University, Uppsala, Sweden.
Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy.
Academy of Industry and Society, Computer Science, Dalarna University, Borlänge, Sweden.ORCID iD: 0000-0002-2372-4226
Department of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden.
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2012 (English)In: Neurological Sciences, ISSN 1590-1874, E-ISSN 1590-3478, Vol. 33, no 4, p. 831-838Article in journal (Refereed) Published
Abstract [en]

Test sequences in a test battery for Parkinson's disease patients, consisting of self-assessments and motor tests, were carried out repeatedly in a telemedicine setting, during week-long test periods and results were summarized in an 'overall score'. 35 patients in stable and fluctuating conditions (15 age- and gender-matched pairs) used the test battery for 1 week, and were then assessed with UPDRS and PDQ-39. This procedure was repeated 1 week later, without treatment changes. Reliability was assessed by intraclass correlation coefficients and Cronbach's alpha. Convergent validity was assessed by Spearman rank correlations and known-groups' validity, by the Mann-Whitney test. According to anonymous usability questionnaires, the patients could easily complete the tasks. Median compliance (93%) and test-retest reliability (0.88) were good. The correlations between overall score and total UPDRS (-0.64) and PDQ-39 (-0.72) were adequate. Median overall score was 18% better in the stable compared to the fluctuating group (p = 0.0014).

Place, publisher, year, edition, pages
Springer, 2012. Vol. 33, no 4, p. 831-838
Keyword [en]
Parkinson's disease; Motor fluctuations; Telemedicine; Self-assessment; Motor tests; Validity
National Category
Computer and Information Sciences Neurology
Research subject
Informatics
Identifiers
URN: urn:nbn:se:oru:diva-61019DOI: 10.1007/s10072-011-0844-5ISI: 000306551000015PubMedID: 22068219Scopus ID: 2-s2.0-84863983754OAI: oai:DiVA.org:oru-61019DiVA, id: diva2:1141384
Funder
Swedish Research Council
Note

Funding Agencies:

Solvay Pharmaceuticals   Allschwil, Switzerland  

Nordforce Technology   Stockholm Sweden 

Available from: 2017-09-14 Created: 2017-09-14 Last updated: 2018-01-13Bibliographically approved

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Memedi, Mevludin

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