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Concentration-Response Relationship between PM2.5 and Daily Respiratory Deaths in China: A Systematic Review and Metaregression Analysis of Time-Series Studies
Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Unit of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Department of Cardiology, Shanghai Changzheng Hospital, Shanghai, China.
Health Outcomes and Economic Evaluation Research Group, Department of Learning, Information, Management and Ethics, Karolinska Institutet, Stockholm, Sweden; Division of Epidemiology and Global Health, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden .
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2017 (English)In: BioMed Research International, ISSN 2314-6133, E-ISSN 2314-6141, 5806185Article, review/survey (Refereed) Published
Abstract [en]

The association between the particulate matters with aerodynamic diameter <= 2.5.mu m (PM2.5) and daily respiratory deaths, particularly the concentration-response pattern, has not been fully examined and established in China. We conducted a systematic review of time-series studies to compile information on the associations between PM2.5 concentration and respiratory deaths and used metaregression to assess the concentration-response relationship. Out of 1,957 studies screened, eleven articles in English and two articles in Chinese met the eligibility criteria. For single-day lags, per 10 mu g/m(3) increase in PM2.5 concentration was associated with 0.30 [95% confidence interval (CI): 0.10, 0.50] percent increase in daily respiratory deaths; for multiday lags, the corresponding increase in respiratory deaths was 0.69 (95% CI: 0.55, 0.83) percent. Difference in the effects was observed between the northern cities and the south cities in China. No statistically significant concentration-response relationship between PM2.5 concentrations and their effects was found. With increasingly wider location coverage for PM2.5 data, it is crucial to further investigate the concentration-response pattern of PM2.5 effects on respiratory and other cause-specific mortality for the refinement and adaptation of global and national air quality guidelines and targets.

Place, publisher, year, edition, pages
Hindawi Publishing Corporation, 2017. 5806185
National Category
Other Medical Biotechnology
Identifiers
URN: urn:nbn:se:oru:diva-62171DOI: 10.1155/2017/5806185ISI: 000413257500001OAI: oai:DiVA.org:oru-62171DiVA: diva2:1155223
Note

Funding Agencies:

Karolinska Institutet Research Assistant Grant  C62400032 

Junior Faculty Grant  C62412022 

Available from: 2017-11-07 Created: 2017-11-07 Last updated: 2017-11-07Bibliographically approved

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Cao, Yang

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