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Prostate cancer and inflammation: The role of miRNAs
Örebro University Hospital. Örebro University, School of Medical Sciences. Department of Urology. (Urologisk cancer)ORCID iD: 0000-0001-5533-7899
Örebro University, School of Medical Sciences. Department of Urology, Örebro University Hospital, Örebro, Sweden.
2013 (English)In: European Medical Journal Oncology, ISSN 2054-619X, p. 56-60Article, review/survey (Refereed) Published
Abstract [en]

Approximately 15-20% of all human cancers are assumed to be a result of infection and chronic inflammation due to a constant supply of cytokines and reactive oxygen species, giving rise to genomic instability and a subsequent tumour development. In recent years, chronic inflammation has also been hypothesised to influence prostate carcinogenesis, since both acute and chronic inflammation is commonly seen in prostatic tissues. The signalling pathways involved in the immune response and tumour development are overlapping with each other, and it has been proposed that miRNAs are a possible link between the two processes. In this review, we are describing some of the miRNAs which could constitute a conceivable link between inflammation and prostate cancer.

Place, publisher, year, edition, pages
United Kingdom: Gorely New Media Ltd. , 2013. p. 56-60
Keywords [en]
miRNA, inflammation, prostate cancer
National Category
Urology and Nephrology Cancer and Oncology
Research subject
Biomedicine
Identifiers
URN: urn:nbn:se:oru:diva-63383OAI: oai:DiVA.org:oru-63383DiVA, id: diva2:1166367
Available from: 2017-12-14 Created: 2017-12-14 Last updated: 2018-04-26Bibliographically approved

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http://emjreviews.com/wp-content/uploads/Prostate-cancer-and-inflammation-The-role-of-miRNAs.pdf

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Carlsson, JessicaDavidsson, Sabina

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