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Antimicrobials: Strategies for targeting obesity and metabolic health?
Alimentary Health Ltd., Cork, Ireland.
Teagasc Moorepark Food Research Centre, Fermoy, Ireland; Department of Microbiology, University College Cork, Cork, Ireland.
Teagasc Moorepark Food Research Centre, Fermoy, Ireland; Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland.ORCID iD: 0000-0001-8591-0799
Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland; Department of Microbiology, University College Cork, Cork, Ireland.
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2013 (English)In: Gut microbes, ISSN 1949-0976, E-ISSN 1949-0984, Vol. 4, no 1, p. 48-53Article in journal (Refereed) Published
Abstract [en]

Obesity is associated with a number of serious health consequences, including type 2 diabetes, cardiovascular disease and a variety of cancers among others and has been repeatedly shown to be associated with a higher risk of mortality. The relatively recent discovery that the composition and metabolic activity of the gut microbiota may affect the risk of developing obesity and related disorders has led to an explosion of interest in this distinct research field. A corollary of these findings would suggest that modulation of gut microbial populations can have beneficial effects with respect to controlling obesity. In this addendum, we summarize our recent data, showing that therapeutic manipulation of the microbiota using different antimicrobial strategies may be a useful approach for the management of obesity and metabolic conditions. In addition, we will explore some of the mechanisms that may contribute to microbiota-induced susceptibility to obesity and metabolic diseases.

Place, publisher, year, edition, pages
Landes Bioscience , 2013. Vol. 4, no 1, p. 48-53
Keywords [en]
Antimicrobials, firmicutes, gut microbiota, metabolic disease, obesity
National Category
Medical and Health Sciences Gastroenterology and Hepatology
Identifiers
URN: urn:nbn:se:oru:diva-65931DOI: 10.4161/gmic.22328PubMedID: 23018760OAI: oai:DiVA.org:oru-65931DiVA, id: diva2:1192020
Available from: 2018-03-21 Created: 2018-03-21 Last updated: 2019-04-24Bibliographically approved

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Marques, Tatiana M.

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