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The role of microRNAs in skeletal muscle health and disease
Center for Muscle Biology, University of Kentucky, Lexington KY, USA; Department of Physiology, College of Medicine, University of Kentucky, Lexington KY, USA.
Center for Muscle Biology, University of Kentucky, Lexington KY, USA; Department of Physiology, College of Medicine, University of Kentucky, Lexington KY, USA.ORCID iD: 0000-0002-5322-4150
Center for Muscle Biology, University of Kentucky, Lexington KY, USA; Department of Physiology, College of Medicine, University of Kentucky, Lexington KY, USA.
2015 (English)In: Frontiers in Bioscience, ISSN 1093-9946, E-ISSN 1093-4715, Vol. 20, p. 37-77Article in journal (Refereed) Published
Abstract [en]

Over the last decade non-coding RNAs have emerged as importance regulators of gene expression. In particular, microRNAs are a class of small RNAs of ∼ 22 nucleotides that repress gene expression through a post-transcriptional mechanism. MicroRNAs have been shown to be involved in a broader range of biological processes, both physiological and pathological, including myogenesis, adaptation to exercise and various myopathies. The purpose of this review is to provide a comprehensive summary of what is currently known about the role of microRNAs in skeletal muscle health and disease.

Place, publisher, year, edition, pages
Irvine, USA: Frontiers in Bioscience , 2015. Vol. 20, p. 37-77
Keywords [en]
MyomiR, Exercise, Hypertrophy, Atrophy, Muscular dystrophy, Review
National Category
Medical and Health Sciences Biochemistry and Molecular Biology
Identifiers
URN: urn:nbn:se:oru:diva-65974DOI: 10.2741/4298ISI: 000354298400002PubMedID: 25553440Scopus ID: 2-s2.0-84918815103OAI: oai:DiVA.org:oru-65974DiVA, id: diva2:1192366
Funder
NIH (National Institute of Health), AR061939Available from: 2018-03-22 Created: 2018-03-22 Last updated: 2018-07-09Bibliographically approved

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Chaillou, Thomas

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