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Multidrug-resistant Neisseria gonorrhoeae failing treatment with ceftriaxone and doxycycline in France, November 2017
Infectious Agents Department, Saint Louis Hospital, APHP, Paris, France; French National Reference Center for bacterial STI, Associated laboratory for gonococci, APHP, Paris, France.
Dermatology Department, CeGGID (Free Information Screening and Diagnostics Centers), Saint Louis Hospital, APHP, Paris, France.
Infectious Agents Department, Saint Louis Hospital, APHP, Paris, France; French National Reference Center for bacterial STI, Associated laboratory for gonococci, APHP, Paris, France.
Infectious Agents Department, Saint Louis Hospital, Assistance Publique – Hôpitaux de Paris (APHP), Paris, France; French National Reference Center for bacterial STI, Associated laboratory for gonococci, APHP, Paris, France; IAME, UMR 1137 Université Paris Diderot, Paris, France.
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2018 (English)In: Eurosurveillance, ISSN 1025-496X, E-ISSN 1560-7917, Vol. 23, no 21, p. 1-3, article id 1800264Article in journal (Refereed) Published
Abstract [en]

We report a multidrug-resistant Neisseria gonorrhoeae urogenital and pharyngeal infection with ceftriaxone resistance and intermediate resistance to azithromycin in a heterosexual woman in her 205 in France. Treatment with ceftriaxone plus doxycycline failed for the pharyngeal localisation. Whole-genome sequencing of isolate F-90 identified MIST1903 , NG-MAST ST343, NG-STAR(233) , and relevant resistance determinants. F-90 showed phenotypic and genotypic similarities to an internationally spreading multidrug-resistant and ceftriaxone-resistant clone detected in Japan and subsequently in Australia, Canada and Denmark.

Place, publisher, year, edition, pages
European Centre for Disease Prevention and Control (ECDC) , 2018. Vol. 23, no 21, p. 1-3, article id 1800264
National Category
Infectious Medicine
Identifiers
URN: urn:nbn:se:oru:diva-67269DOI: 10.2807/1560-7917.ES.2018.23.21.1800264ISI: 000433285600002Scopus ID: 2-s2.0-85048024503OAI: oai:DiVA.org:oru-67269DiVA, id: diva2:1219028
Note

Funding Agency:

French National Public Health Agency (Saint Maurice, France) 

Available from: 2018-06-15 Created: 2018-06-15 Last updated: 2018-09-14Bibliographically approved

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Unemo, Magnus

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