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Patient-reported Outcomes In Relation To Continuously Monitored Rhythm Before And During Two Years After Atrial Fibrillation Ablation Using A Disease-specific And A Generic Instrument
Örebro University, School of Medical Sciences. Örebro University Hospital. Department of Cardiology.
Odense University Hospital, Odense, Denmark.
Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden.
Department of Cardiology, Odense University Hospital, Odense, Denmark, Odense, Denmark.
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2018 (English)Conference paper, Poster (with or without abstract) (Refereed)
Abstract [en]

Background: Patients with AF have a lower health-related quality of life (HRQoL) than the general population.

Objective: To assess the effect of AF ablation on AF-specific and generic patient-reported outcomes (PRO), compare it to a Swedish age- and sex-matched population and evaluate any association with the AF burden.

Methods: Patients scheduled for AF ablation completed the generic SF-36 and the AF-specific PRO questionnaires before and six, 12 and 24 months after AF ablation. All patients underwent continuous ECG monitoring via an implantable loop recorder.

Results: 54 patients completed the follow-up. After ablation, the generic SF-36 improved and both summary scores reached normative levels at 24 months, while physical functioning, role-physical and vitality remained lower than norms. Responders with an AF burden ≤0.5% at each visit after ablation reached the norms in all domains, while non-responders reached norms in only social functioning and MCS. All AF6 items and the sum score showed moderate to large improvement in both responders and non-responders. Higher AF burden was independently associated with poorer PCS and AF6 sum score. The AF sum score correlated with all SF-36 domains, but all AF6 items did not correlate with the SF-36 summary scores.

Conclusion: The AF-specific AF6 questionnaire was more sensitive to changes in PRO related to AF burden than was the generic SF-36. Higher AF burden after ablation was associated with poorer AF-specific PRO and poorer generic physical but not mental health. Focusing on AF-specific symptoms and their impact on quality of life as an outcome after AF ablation is reasonable, as improving PROs is the main goal of AF ablation.

Place, publisher, year, edition, pages
2018.
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:oru:diva-69425OAI: oai:DiVA.org:oru-69425DiVA, id: diva2:1254324
Conference
HRS 39th Annual Scientific Sessions, Boston, USA, May 9-12, 2018
Available from: 2018-10-09 Created: 2018-10-09 Last updated: 2018-10-09Bibliographically approved

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Björkenheim, AnnaPoci, Ditran

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CiteExportLink to record
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  • harvard1
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