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Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018
Örebro University, School of Medical Sciences. WHO Collaborating Centre for Gonorrhoea and other Sexually Transmitted Infections, Swedish Reference Laboratory for Sexually Transmitted Infections, Department of Laboratory Medicine, Clinical Microbiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Department of Clinical Microbiology, University of Dublin, Trinity College, St. James’s Hospital, Dublin, Ireland.
Guide Clinic, St. James’s Hospital, Dublin, Ireland.
Department of Clinical Microbiology, University of Dublin, Trinity College, St. James’s Hospital, Dublin, Ireland.
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2018 (English)In: Eurosurveillance, ISSN 1025-496X, E-ISSN 1560-7917, Vol. 23, no 47, p. 6-9, article id 1800617Article in journal (Refereed) Published
Abstract [en]

We describe a multidrug-resistant Neisseria gonorrhoeae urethritis case with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Ireland, August 2018. Whole-genome sequencing showed that the isolate IR72 belongs to the internationally spreading multidrug-resistant ceftriaxone-resistant FC428 clade, initially described in Japan in 2015. IR72 was assigned MSLT ST1903, NG-MAST ST17842 and NG-STAR type 1133, including the ceftriaxone resistance-mediating penA-60.001. Global awareness of spreading ceftriaxone-resistant gonococcal strains that threaten recommended dual therapies is essential.

Place, publisher, year, edition, pages
European Centre for Disease Prevention and Control (ECDC) , 2018. Vol. 23, no 47, p. 6-9, article id 1800617
National Category
Infectious Medicine
Identifiers
URN: urn:nbn:se:oru:diva-70495DOI: 10.2807/1560-7917.ES.2018.23.47.1800617ISI: 000450915700002PubMedID: 30482267Scopus ID: 2-s2.0-85057267850OAI: oai:DiVA.org:oru-70495DiVA, id: diva2:1268308
Note

Funding Agencies:

St. James Hospital, Dublin, Ireland   Örebro County Council Research Committee  

Foundation for Medical Research at Örebro University Hospital, Örebro, Sweden 

Available from: 2018-12-05 Created: 2018-12-05 Last updated: 2018-12-05Bibliographically approved

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Golparian, DanielUnemo, Magnus

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