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Antibiotic resistance and NG-MAST sequence types of Neisseria gonorrhoeae isolates in Poland compared to the world
Department of Diagnostics of Sexually Transmitted Diseases, Medical University of Warsaw, Warsaw, Poland.
Department of Diagnostics of Sexually Transmitted Diseases, Medical University of Warsaw, Warsaw, Poland.
Department of Dermatology and Venereology, Medical University of Warsaw, Warsaw, Poland.
Örebro University, School of Medical Sciences. Örebro University Hospital. World Health Organization (WHO) Collaborating Centre for Gonorrhoea and other STIs.ORCID iD: 0000-0003-1710-2081
2018 (English)In: Advances in Dermatology and Allergology / Postępy Dermatologii i Alergologii, ISSN 1642-395X, Vol. 35, no 6, p. 546-551Article, review/survey (Refereed) Published
Abstract [en]

Gonorrhoea is one of the most common sexually transmitted infections and in 2012, the World Health Organization estimated about 78 million of new global urogenital cases among adults per year. The main concern during the latest decade has been the emergence and spread of multidrug-resistant strains of Neisseria gonorrhoeae. Resistance has emerged internationally to the extended-spectrum cephalosporins, ceftriaxone and cefixime, which are the last remaining options for empiric first-line monotherapy of gonorrhoea. In Poland, the levels of resistance to ciprofloxacin, benzylpenicillin and tetracycline are high, and the prevalence of azithromycin resistance has increased. However, no resistance to ceftriaxone has been identified. The currently spread multidrug-resistant strains frequently represent epidemic clones. The present paper reviews and describes the antimicrobial resistance and N. gonorrhoeae multiantigen sequence typing (NG-MAST) sequence types of N. gonorrhoeae strains spreading in Poland compared to the world.

Place, publisher, year, edition, pages
Termedia Publishing , 2018. Vol. 35, no 6, p. 546-551
Keywords [en]
Neisseria gonorrhoeae, gonorrhoea, antimicrobial resistance, ceftriaxone, azithromycin, NG-MAST, sequence type, genogroup
National Category
Dermatology and Venereal Diseases
Identifiers
URN: urn:nbn:se:oru:diva-71168DOI: 10.5114/ada.2018.79780ISI: 000453022600002Scopus ID: 2-s2.0-85058817744OAI: oai:DiVA.org:oru-71168DiVA, id: diva2:1276421
Available from: 2019-01-08 Created: 2019-01-08 Last updated: 2019-01-08Bibliographically approved

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