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Patterns of diagnostic transition in eating disorders: a longitudinal population study in Sweden
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet,Stockholm, Sweden.
Department of Psychiatry, University of North Carolina at Chapel Hill,Chapel Hill, NC,USA.
Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet and Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.
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2019 (English)In: Psychological Medicine, ISSN 0033-2917, E-ISSN 1469-8978, Vol. 49, no 5, p. 819-827Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Transition across eating disorder diagnoses is common, reflecting instability of specific eating disorder presentations. Previous studies have examined temporal stability of diagnoses in adult treatment-seeking samples but have not uniformly captured initial presentation for treatment. The current study examines transitions across eating disorder diagnostic categories in a large, treatment-seeking sample of individuals born in Sweden and compares these transitions across two birth cohorts and from initial diagnosis.

METHODS: Data from Swedish eating disorders quality registers were extracted in 2013, including 9622 individuals who were seen at least twice from 1999 to 2013. Patterns of remission were examined in the entire sample and subsequently compared across initial diagnoses. An older (born prior to 1990) and younger birth cohort were also identified, and analyses compared these cohorts on patterns of diagnostic transition.

RESULTS: Although diagnostic instability was common, transition between threshold eating disorder diagnoses was infrequent. For all diagnoses, transition to remission was likely to occur following a diagnosis state that matched initial diagnosis, or through a subthreshold diagnostic state. Individuals in the younger cohort were more likely to transition to a state of remission than those in the older cohort.

CONCLUSIONS: Results indicate more temporal continuity in eating disorder presentations than suggested by previous research and highlight the importance of early detection and intervention in achieving remission.

Place, publisher, year, edition, pages
Cambridge University Press, 2019. Vol. 49, no 5, p. 819-827
Keywords [en]
Anorexia nervosa, binge-eating disorder, bulimia nervosa, classification, crossover, diagnosis, eating disorders
National Category
Medical and Health Sciences Psychiatry
Identifiers
URN: urn:nbn:se:oru:diva-71747DOI: 10.1017/S0033291718001472ISI: 000461660000012PubMedID: 29911514Scopus ID: 2-s2.0-85048794237OAI: oai:DiVA.org:oru-71747DiVA, id: diva2:1281865
Funder
Swedish Research Council, 538-2013-8864
Note

Funding Agencies:

Swedish Initiative for Research on Microdata in the Social and Medical Sciences (SIMSAM) framework

National Institute of Mental Health

Anorexia Nervosa Genetics Initiative (ANGI), an initiative of the Klarman Family Foundation

Foundation of Hope: Research and Treatment of Mental Illness 

Available from: 2019-01-23 Created: 2019-01-23 Last updated: 2019-06-18Bibliographically approved

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