Core outcome domains in incontinence-associated dermatitis researchShow others and affiliations
2018 (English)In: Journal of Advanced Nursing, ISSN 0309-2402, E-ISSN 1365-2648, Vol. 74, no 7, p. 1605-1617Article in journal (Refereed) Published
Abstract [en]
AIM: To report the development of a core set of outcome domains for clinical research involving adults with incontinence-associated dermatitis or at risk, independently from any geographical location or skin colour.
BACKGROUND: The management of incontinence-associated dermatitis is important in caring for incontinent patients. The lack of comparability of clinical trial outcomes is a major challenge in the field of evidence-based incontinence-associated dermatitis prevention and treatment. Core outcome sets may therefore be helpful to improve the value of clinical incontinence-associated dermatitis research.
DESIGN: Systematic literature review, patient interviews and consensus study using Delphi procedure.
METHODS: A list of outcome domains was generated through a systematic literature review (no date restrictions-April 2016), consultation of an international steering committee and three patient interviews. The project team reviewed and refined the outcome domains prior to starting a three-round Delphi procedure conducted between April-September 2017. The panellists, including healthcare providers, researchers and industry were invited to rate the importance of the outcome domains.
RESULTS: We extracted 1,852 outcomes from 244 articles. Experts proposed 56 and patients 32 outcome domains. After refinement, 57 panellists from 17 countries rated a list of 58 outcome domains. The final list of outcome domains includes erythema, erosion, maceration, IAD-related pain and patient satisfaction.
CONCLUSION: Erythema, erosion, maceration, incontinence-associated dermatitis -related pain and patient satisfaction are the most important outcome domains to be measured in incontinence-associated dermatitis trials. Based on this international consensus on what to measure, the question of how to measure these domains now requires consideration. Registration: This project has been registered in the Core Outcome Measures in Effectiveness Trials (COMET Initiative) database and is part of the Cochrane Skin Group-Core Outcomes Set Initiative (CSG-COUSIN).
Place, publisher, year, edition, pages
Blackwell Publishing, 2018. Vol. 74, no 7, p. 1605-1617
Keywords [en]
Clinical nursing research, contact dermatitis, core outcome set, dermatology, domains, incontinence-associated dermatitis, nursing, outcome assessment, outcomes, outcomes research
National Category
Nursing
Identifiers
URN: urn:nbn:se:oru:diva-73166DOI: 10.1111/jan.13562ISI: 000435939500017PubMedID: 29520848Scopus ID: 2-s2.0-85044849573OAI: oai:DiVA.org:oru-73166DiVA, id: diva2:1296495
Note
Funding agency:
Ghent University Special Research Fund
2019-03-152019-03-152019-06-18Bibliographically approved