To Örebro University

oru.seÖrebro University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
In-hospital physiotherapy improves physical activity level after lung cancer surgery: a randomized controlled trial
Örebro University, School of Medical Sciences. Department of Physiotherapy.ORCID iD: 0000-0001-8186-8562
Örebro University, School of Health Sciences. Department of Medical Diagnostics.ORCID iD: 0000-0003-1067-8627
Cardiovascular Division, Karolinska University Hospital, Stockholm, Sweden.
Department of Vascular and Cardiothoracic Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Show others and affiliations
2019 (English)In: Physiotherapy, ISSN 0031-9406, E-ISSN 1873-1465, Vol. 105, no 4, p. 434-441Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: Patients undergoing lung cancer surgery are routinely offered physiotherapy. Despite its routine use, effects on postoperative physical recovery have yet not been demonstrated. The aim of this study was to investigate whether physiotherapy could improve postoperative in-hospital physical activity level and physical capacity.

DESIGN: Single-blind randomized controlled trial.

SETTING: Thoracic surgery department at a University Hospital.

PARTICIPANTS: Patients undergoing elective thoracic surgery (n=94) for confirmed or suspected lung cancer were assessed during hospital stay.

INTERVENTION: Daily physiotherapy, consisting of mobilization, ambulation, shoulder exercises and breathing exercises. The control group received no physiotherapy treatment.

OUTCOMES: In-hospital physical activity assessed with the Actigraph GT3X+ accelerometer, six-minute walk test, spirometry and dyspnea scores.

RESULTS: The treatment group reached significantly more accelerometer counts (2010 (1508) vs 1629 (1146), mean difference 495 [95% CI 44 to 1109]), and steps per hour (49 (47) vs 37 (34), mean difference 14 [95% CI 3 to 30]), compared to the control group, during the first three postoperative days. No significant differences in six-minute walk test (percent of preoperative 71% vs 79%, P=0.13), spirometry (FEV1 percent of preoperative 69% vs 69%, P=0.83) or dyspnoea (M-MRC 2 vs 2, P=0.74) between the groups were found.

CONCLUSIONS: Patients receiving in-hospital physiotherapy showed increased level of physical activity during the first days after lung cancer surgery, compared to an untreated control group. However, no effects on the six-minute walk test or spirometric values were found. The clinical importance of an increased physical activity level during the early postoperative period needs to be further evaluated.

CLINICAL TRIAL REGISTRATION NUMBER: NCT01961700.

Place, publisher, year, edition, pages
Elsevier, 2019. Vol. 105, no 4, p. 434-441
Keywords [en]
Lung cancer, Physical activity, Physical therapy, Randomized clinical trial
National Category
Surgery Cancer and Oncology
Identifiers
URN: urn:nbn:se:oru:diva-73624DOI: 10.1016/j.physio.2018.11.001ISI: 000496916200005PubMedID: 30871894Scopus ID: 2-s2.0-85062599637OAI: oai:DiVA.org:oru-73624DiVA, id: diva2:1303601
Funder
Swedish Cancer Society, CAN 2015/721
Note

Funding Agencies:

Research Committee of Örebro County Council  OLL363321 OLL-686781

Swedish Heart and Lung Patients National Association  E o86/13

Available from: 2019-04-10 Created: 2019-04-10 Last updated: 2024-03-06Bibliographically approved
In thesis
1. Physiotherapy and physical activity in patients undergoing cardiac or lung cancer surgery
Open this publication in new window or tab >>Physiotherapy and physical activity in patients undergoing cardiac or lung cancer surgery
2019 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Cardiovascular diseases are the leading cause of death worldwide. Cardiac surgery is performed to improve prognosis, relieve symptoms and increase functional capacity in patients with cardiac disease. Postoperative pulmonary complications are common after cardiac surgery and a reduced lung function can persist a long time after surgery. A positive association between level of physical activity and lung function has been proposed in both healthy individuals and people with different disabilities. It is not clear if there is an association between level of physical activity and recovery of lung function after cardiac surgery. Lung cancer is one of the most frequently diagnosed forms of cancer worldwide, and a leading cause of cancer deaths. Surgical resection is the primary approach for curative treatment. Despite the fact that physical activity has many positive effects on health, patients undergoing lung cancer surgery often report a low level of physical activity. Measuring physical activity is not easy, self-reported physical activity remains the most clinically applicable type of measurement, and a simple and valid questionnaire for screening patients would be valuable. Patients undergoing lung cancer surgery are often routinely treated by physiotherapists, but this kind of treatment has not been thoroughly investigated. The purpose of this thesis was to investigate the effect of physiotherapy and physical activity in patients undergoing cardiac or lung cancer surgery. This thesis include one cohort study of physical activity and recovery of lung function in patients undergoing cardiac surgery, one validation study of two self-reported physical activity instruments in patients undergoing lung cancer surgery, and two randomized controlled trials investigating the effect of physiotherapy for patients undergoing lung cancer surgery. In study I, patients who remained active or increased their level of physical activity had better recovery of lung function, compared to patients who remained sedentary or reported a lower level of physical activity postoperatively. In study II, two self-reported physical activity instruments were validated against accelerometer data in patients three and twelve months after lung cancer surgery. Both instruments were found able to identify patients not meeting recommendations on physical activity. In study III, patients treated by physiotherapists were significantly more active during the first three days after lung cancer surgery, compared to an untreated control group. In study IV, no between-group differences three months after surgery were found between patients receiving in-hospital physiotherapy compared to an untreated control group. However, the patients in the treatment group reported an increase of physical activity three months after surgery compared to preoperatively, while the patients in the control group did not.

Place, publisher, year, edition, pages
Örebro: Örebro University, 2019. p. 59
Series
Örebro Studies in Medicine, ISSN 1652-4063 ; 192
Keywords
Physiotherapy, Physical Activity, Cardiac surgery, Lung Cancer, Randomized Controlled Trial, Thoracic surgery, Physical Function, Lung Function
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-72411 (URN)978-91-7529-282-3 (ISBN)
Public defence
2019-05-03, Örebro universitet, Campus USÖ, hörsal C2, Södra Grev Rosengatan 32, Örebro, 13:00 (Swedish)
Opponent
Supervisors
Available from: 2019-02-12 Created: 2019-02-12 Last updated: 2024-03-06Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMedScopus

Authority records

Jonsson, MarcusHurtig-Wennlöf, AnitaVidlund, MårtenCao, YangWesterdahl, Elisabeth

Search in DiVA

By author/editor
Jonsson, MarcusHurtig-Wennlöf, AnitaVidlund, MårtenCao, YangWesterdahl, Elisabeth
By organisation
School of Medical SciencesSchool of Health SciencesÖrebro University Hospital
In the same journal
Physiotherapy
SurgeryCancer and Oncology

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 602 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf