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Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Orebro County, Sweden, May 2019
Örebro University, School of Medical Sciences. Örebro University Hospital. World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections (STIs), National Reference Laboratory for STIs, Department of Laboratory Medicine.ORCID iD: 0000-0003-1710-2081
World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections (STIs), National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections (STIs), National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Department of Laboratory Medicine, Medical Microbiology, Lund University, Skåne Laboratory Medicine, Lund, Sweden.
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2019 (English)In: Eurosurveillance, ISSN 1025-496X, E-ISSN 1560-7917, Vol. 24, no 26, p. 10-14, article id 1900370Article in journal (Refereed) Published
Abstract [en]

We identified the first two cases of the Finnish new variant of Chlamydia trachomatis (F-nvCT) beyond Finland in two clinical urogenital specimens in Orebro County, Sweden. These Aptima Combo 2 assay-negative specimens were Aptima Chlamydia trachomatis (CT) assay positive and had the characteristic C1515T mutation in the 23S rRNA gene. From 22 March to 31 May 2019, 1.3% (2/158) of the CT-positive cases in Orebro County were missed because of the F-nvCT. International awareness, investigations and actions are essential.

Place, publisher, year, edition, pages
European Centre for Disease Prevention and Control , 2019. Vol. 24, no 26, p. 10-14, article id 1900370
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Infectious Medicine
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URN: urn:nbn:se:oru:diva-75223DOI: 10.2807/1560-7917.ES.2019.24.26.1900370ISI: 000473116300003PubMedID: 31266590OAI: oai:DiVA.org:oru-75223DiVA, id: diva2:1339150
Available from: 2019-07-26 Created: 2019-07-26 Last updated: 2019-07-26Bibliographically approved

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Unemo, MagnusSundqvist, Martin

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