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Informatics and computational strategies for the study of lipids
VTT Technical Research Centre of Finland, Espoo, Finland .
VTT Technical Research Centre of Finland, Espoo, Finland.
University of Cambridge Department of Clinical Biochemistry, Addenbrooke's Hospital, Hills Road, Cambridge, UK.
VTT Technical Research Centre of Finland, Espoo, Finland.ORCID iD: 0000-0002-2856-9165
2008 (English)In: Molecular Biosystems, ISSN 1742-206X, E-ISSN 1742-2051, Vol. 4, no 2, p. 121-127Article in journal (Refereed) Published
Abstract [en]

Recent advances in mass spectrometry (MS)-based techniques for lipidomic analysis have empowered us with the tools that afford studies of lipidomes at the systems level. However, these techniques pose a number of challenges for lipidomic raw data processing, lipid informatics, and the interpretation of lipidomic data in the context of lipid function and structure. Integration of lipidomic data with other systemic levels, such as genomic or proteomic, in the context of molecular pathways and biophysical processes provides a basis for the understanding of lipid function at the systems level. The present report, based on the limited literature, is an update on a young but rapidly emerging field of lipid informatics and related pathway reconstruction strategies.

Place, publisher, year, edition, pages
Royal Society of Chemistry, 2008. Vol. 4, no 2, p. 121-127
National Category
Bioinformatics and Systems Biology
Identifiers
URN: urn:nbn:se:oru:diva-70914DOI: 10.1039/b715468bISI: 000252553500003PubMedID: 18213405Scopus ID: 2-s2.0-38549111882OAI: oai:DiVA.org:oru-70914DiVA, id: diva2:1345860
Available from: 2019-08-26 Created: 2019-08-26 Last updated: 2019-08-27Bibliographically approved

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Oresic, Matej

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